Decasan

Dekasan is an effective antiseptic, a bis-quaternary ammonium derivative. It is intended for external use: mainly for washing wounds and affected skin surfaces.

Approved for over-the-counter release.

[ 1 ], [ 2 ], [ 3 ]

Indications Decasana

• Skin pathologies (bacterial, purulent or fungal etiology, as well as eczematous rashes of microbial origin).
• Inflammatory-purulent skin pathologies with the presence of open wound surfaces and the need to install drainage (furunculosis, carbunculosis, digital felon, wound infections, purulent process in adipose tissue, etc.).
• Inflammation of the oral mucosa (gum disease, periodontal disease).
• Inflammatory processes of the bronchopulmonary system.
• Inflammatory phenomena in the colon and genitourinary system.
• For disinfection of cavities and superficial wounds, surgical instruments, equipment, etc.

Release form

Dekasan is a 0.02% solution of decamethoxin with saline solution.

Available in bottles of 50, 100, 200, 400 ml, or in polymer bags of 50, 100, 250, 500 ml, 1 l, 2 l, 3 l and 5 l.

Pharmacodynamics

Decasan exhibits:

• pronounced bactericidal properties against staphylococcal, streptococcal, diphtheria infections, pseudomonas and encapsulated bacteria;
• fungicidal properties against yeast and mold fungi, pathogens of erythrasma, trichophytosis, epidermophytosis, microsporia;
• antiprotozoal effect on giardiasis and trichomoniasis;
• antivirus capabilities.

Decasan is especially effective against bacteria resistant to antibiotic therapy (treatment with penicillin, tetracycline, erythromycin, etc.). Resistance to Decasan itself develops very slowly.

Pharmacokinetics

The external use product does not penetrate into the systemic bloodstream from intact skin, mucous and wound surfaces. For this reason, there is no data on the pharmacokinetic properties of Decasan.

Dosing and administration

Standard Decasan solution is most often used in dermatological practice for wiping, washing skin areas, or for applying lotions.

When fistulas are formed, intrafistular lavage is practiced. Duration of therapy is up to 5 days.

In urology, the solution is used in the treatment of chronic inflammatory processes in the urethra and bladder, diluted in advance with boiled or distilled water in a ratio of 1 to 7. About half a liter of the resulting liquid is used for rinsing. The duration of therapy is approximately 20 procedures.

In case of colon pathologies and inflammation of the prostate gland, a warm solution is used as an enema twice a day, no more than 100 ml, until the signs of the acute period of the disease are completely relieved.

In case of oral pathologies, the medicine is used for irrigation (100-150 ml) or lotions for 10-15 minutes. For the treatment of periodontal diseases (I-II st.) with the presence of dystrophic and inflammatory processes, the gum pockets are washed with warm Dekasan. It is possible to simultaneously apply napkins soaked in the solution to the affected gums until the signs of the inflammatory reaction are eliminated. In case of ulcers of the mucous membranes, thrush, the medicine is used for rinsing up to 5 times a day. The duration of therapy is at least 10 days.

Chronic tonsillitis requires frequent washing and rinsing of the tonsils. Simultaneous washing of the nasopharynx is recommended.

For intrabronchial use of Dekasan (for purulent bronchiectasis, hypoplasia, acute period of chronic inflammation in the bronchi), the following treatment regimen is prescribed:

• microtracheostomal method – no more than 50 ml twice a day;
• transnasal catheterization – no more than 10 ml once a day;
• inhalation ultrasound method – no more than 10 ml up to 2 times a day;
• tracheobronchial lavage – no more than 100 ml.

Duration of therapy: 14-30 days.

To relieve inflammation of the external genitalia, the solution can be used for douching. Dekasan is heated to body temperature and administered with a syringe, about 100 ml three times a day. The birth canal can be disinfected in the same way before childbirth. After childbirth, the drug is used, if necessary, to treat signs of endometritis: the uterine cavity is washed twice a day with heated Dekasan liquid, in an amount of no more than 200 ml.

Disinfection of consumables and instruments in medicine is carried out by rinsing and soaking for 5 to 30 minutes.

Use Decasana during pregnancy

During pregnancy and breastfeeding, the use of Dekasan is not prohibited, since the drug does not penetrate the outer layers into the circulatory system.

Contraindications

The only contraindication to the use of Decasan is individual intolerance to the drug.

Side effects Decasana

The external antiseptic Dekasan can cause allergic reactions, which are manifested by reddening of the skin, itchy rashes. Usually, such symptoms do not require any additional treatment measures and are completely relieved after stopping the use of the drug.

When the drug is administered intrabronchially, a transient burning sensation in the chest may occur, which disappears without a trace within 30 minutes.

[ 4 ]

Overdose

Decasan does not have the property of penetrating into the systemic circulation when used superficially, therefore the possibility of an overdose of the drug is excluded.

Interactions with other drugs

Decasan cannot be used simultaneously with detergents and agents, as they neutralize the properties of the drug.

Decasan enhances the destructive effect of antibiotics on pathogenic microflora.

[ 5 ]

Storage conditions

The medicine should be stored in a dark place, out of reach of children. Optimum temperature is from +18°C to +25°C.

[ 6 ]

Special instructions

Important: Decasan can have a more pronounced effect if the solution is preheated to 37-38°C.

Shelf life

Shelf life is up to 3 years if the solution is stored in accordance with all recommendations.