De Nol

De-Nol has an active effect on diseases of the gastrointestinal tract. To date, many people suffer from problems with this system. Improper eating, eating on the go, not following a certain regime and heredity, all this leads to the development of all sorts of problems. To correct the situation and alleviate the symptoms, special symptomatic therapy is performed.

[1], [2], [3], [4], [5], [6], [7], [8], [9]

Indications De Nol

The main indications for the use of De-Nol are the use of the drug in the period of exacerbation of the disease of the gastrointestinal tract. Take the remedy for peptic ulcer and duodenal ulcer. In the latter case, this is most relevant in cases when there is a phase of exacerbation, which could be associated with Helicobacter pylori.

Chronic gastritis is also the main indication for the use of the drug. This category also includes gastroduodenitis, which is in the acute phase of exacerbation. It can also be associated with Helicobacter pylori.

Irritable bowel syndrome is affected by this medication. Especially if it occurs with symptoms of diarrhea. Functional dyspepsia, which is not associated with organic diseases by the gastrointestinal tract, can be eliminated through the medication. De-Nol has a wide range of effects on the stomach, so it shortens the acute manifestations of any disease in a short time. 

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Release form

Tablets, covered with a special shell, this is the form of release of the medicine. One blister can contain up to 14 tablets. Each of them has its own special coating. The amount of active ingredient in the tablet is 120 mg.

There is another form of release, it's also a pill, but there are only 7 of them in the blister pack. In one box can be up to 8 blisters. The medication is taken quite often, which is why it has such a large "packaging".

In the form of suspensions, the drug is not supplied, because one pill is enough. One capsule contains a sufficient amount of active substance, which can cause relief in a few minutes. Naturally, if we are not talking about acute manifestations of diseases.

It is advisable to consult a doctor before buying. He will tell you how many tablets you need to buy. After all, much depends on the disease itself, its stage and development. De-Nol is a powerful remedy that eliminates all the unpleasant symptoms associated with the organs of the gastrointestinal tract. 

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Pharmacodynamics

The medicine has excellent antiseptic actions, this is pharmacodynamics. Medication can eliminate the symptoms of diseases associated with the organs of the gastrointestinal tract.

The product has a remarkable antiulcer effect. It relaxes, the main symptoms and allows you to eventually eliminate the ulcer. De-Nol stimulates the formation of mucus, increases the synthesis and secretion of hydrocarbons.

To date, this tool is one of the most effective of its kind. It actively removes the effects of ulcers and soothes the manifestation of chronic gastritis. The medication is mandatory in many cases. The main thing before this is to get a doctor's advice.

The medicine is not practically absorbed from the organs of the gastrointestinal tract. It is displayed together with feces. A small amount of bismuth, which entered the plasma, can be excreted with the kidneys. De-Nol is not retained in the body and eventually completely eliminated. 

[12], [13], [14], [15], [16], [17], [18], [19], [20]

Pharmacokinetics

Pharmacokinetics - the active substance of the drug is not absorbed from the organs of the gastrointestinal tract. After a while, the medication is completely removed from the body along with the feces. Only a small part of it can be excreted by the kidneys. But this is the case when bismuth enters the blood plasma.

The active component of the drug is bismuth. It is he who has a positive effect on the body as a whole and allows you to deal with many problems. The main action is aimed at stimulating the development of mucus, which protects the gastrointestinal tract from the negative effects of inflammation.

The product has a remarkable antiulcer effect. Therefore, people suffering from a duodenal ulcer should take this medication. But this is done only after consulting a doctor.

Chronic gastritis is now not terrible, because De-Nol is able to fight with its active phase and eliminate the effects of severe exacerbation. But for this, complex treatment and constant therapy with the use of De-nol is necessary. 

[21], [22], [23], [24], [25], [26], [27], [28]

Dosing and administration

The way of application and the dose of De-Nol directly depend on the disease that people suffer. Basically, the medicine is applied inside and at the same time is washed down with a lot of water.

Adults and children over 12 years of age should take one tablet up to 4 times a day. Admission is 30 minutes before meals. At night, it is also recommended that you take a medicine in the amount of 2 tablets. A slightly different scheme of medication is possible. In this case, it is taken 2 tablets twice, also 30 minutes before a meal.

Children aged 8 to 12 years should drink 1 tablet 2 times a day for a day. All this is done 30 minutes before meals. Babies from 4 to 8 years should drink 8 mg of medicament per kilogram of weight. The daily dosage must necessarily be divided into two doses.

The course of treatment does not exceed 2 months. In this case, much depends on the disease, its stage and course. After 2 months, it is mandatory to exclude the use of drugs, the active substance of which is bismuth. De-Nol relieves unpleasant symptoms and alleviates a person's condition for a long time. 

[42], [43], [44], [45], [46], [47], [48], [49]

Use De Nol during pregnancy

Contraindicated use of De-Nol during pregnancy. The composition of the medicine contains powerful active substances, they are able to have a negative effect on the developing organism.

The fact is that in the early stages of pregnancy, many drugs are prohibited. The mother's body is too weak and does not fulfill its protective functions. The same can be said about the baby. A developing organism should not be affected by negative factors, especially in the early stages. This can worsen the development of the child and lead to pathologies.

In the period of breastfeeding, it is also worth noting the use of the drug. After all, its active ingredients can penetrate the baby's body together with milk. All this can lead to the development of negative factors. Therefore, if there is an urgent need for the use of a medicine, it is worth consulting with a doctor. It is likely there is an opportunity to avoid this. Otherwise, De-Nol can cause the development of irreversible processes. 

Contraindications

Contraindications to the use of De-Nol mainly consist of a persistent intolerance to the active components of the drug. Therefore, with individual intolerance, it is worthwhile to refrain from taking the medication.

Violation of kidney function and taking the remedy are unacceptable. After all, most of the medicine is excreted through these organs. If this is not possible, the active substances will remain inside the body. This can lead to the development of serious problems.

During pregnancy, it is strictly forbidden to take De-Nol. Even if everything develops quite normally, there may be side effects. The period of breastfeeding is also under special prohibition, because active substances can penetrate the woman's milk, and then into the baby's body.

In any case, you should not start taking the medication yourself. After all, you need to calculate a special dosage, which is directly related to the disease and its manifestation. In addition, you need to check how the body reacts to taking De-Nol and only, then begin complex treatment. 

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Side effects De Nol

Side effects of De-Nol manifest themselves mainly from the digestive system and in the form of allergic reactions. So, it is possible the appearance of nausea, vomiting and frequent stool, and constipation is possible. All these side effects do not carry any danger. Basically they are temporary. As soon as the body gets used to the medicine, all the troubles will disappear.

Allergic reactions are also possible. They appear in the form of a rash on the skin and severe itching. Most likely, the body still has a certain sensitivity to the drug. It is advisable to seek medical help from a doctor and, if necessary, replace the medication with another, or reduce the dosage.

If the medicine is taken for a long time, then the development of encephalopathy is possible. This is due to the significant accumulation of bismuth in the central nervous system.

If side effects do not go away with time, it is worth stopping the medication. Most likely, De-Nol is not perceived by the body, resulting in negative symptoms. 

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Overdose

Do not overdose De-nol, but only if the drug was taken in too high a dose. This also appears during long-term use of the medication. The main symptoms of the drug are a violation of kidney function. If you cancel the medication, then everything will fall into place.

What to do if there is an overdose? In this case, the stomach is washed without fail. It is necessary to appoint the reception of activated charcoal and saline laxatives.

Subsequently, it is necessary to resort to symptomatic therapy. If renal impairment is accompanied by a high level of bismuth in the blood plasma, then complex treatment should be used. In this case, dimercaptosuccinic and dimercaptopropanesulfonic acids will help.

If renal impairment is clearly pronounced, then hemodialysis is prescribed. In any case, if you have symptoms of an overdose, you should cancel taking the drug De-nol. 

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Interactions with other drugs

It is not excluded and interactions with other drugs. Within 30 minutes before and after taking the medication, you can not take other drugs. The same is true for eating food and liquids. It is necessary to exclude from the diet milk, fruit and fruit juices. This can cause negative reactions from the gastrointestinal tract.

With simultaneous ingestion of irritating food and medication can affect the effectiveness of De-nol. In this case, the appearance of negative factors is possible, as well as the complete absence of relief after taking the drug.

During treatment of the stomach, you need to completely exclude acidic food and other harmful products. This can aggravate the situation. In addition, there may be a manifestation of inactivity on the part of the drug. Therefore, it is better to consult a doctor, so as not to aggravate the situation on your own and to prevent the development of serious problems. De-Nol is a wonderful drug, but if it does not interact well with others it can be harmful.  

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Storage conditions

De-Nol storage conditions must be observed in full. So, it is desirable that the storage temperature does not exceed 25 degrees. It is important to find the optimal storage location.

A dry place in which there is no sunlight, just such should be the optimal performance. Many people do not store medicines in the medicine cabinet, which allows the children to easily reach them. In addition, these do not allow you to fulfill certain storage conditions. As a result, the drug deteriorates, and becomes unsuitable for use.

Drugs do not like dampness, it negatively affects them. In this case, the loss of the main positive properties of the drug is not excluded. Do not store the medication in the refrigerator. This increases the risk of deterioration of the basic qualities of the product, and also allows the children to reach it freely. Therefore, it is best to give preference to the ordinary medicine cabinet. De-Nol does not require observance of certain storage conditions, these are standard indicators, so in this case it is necessary to start from the temperature regime. 

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Shelf life

Shelf life of the medication is 48 months. Unlike suspensions, tablets can be stored after opening for a specified time. On this occasion, you should not even worry.

But, despite this, it is necessary to pay attention to what the blister looks like. If it is damaged, has punctures or pills, the pills are opened, then you can not take the medicine. Any mechanical damage jeopardizes everything.

Significantly shorten the shelf life may also cause improper storage conditions. Therefore, it is worth immediately preparing for the tablets a place in the medicine cabinet, it is here that all the optimal conditions are observed. No dampness, there is a necessary temperature regime, and there is no possibility of penetration of direct sunlight.

It is necessary to follow the appearance of the medication. The color and odor should remain unchanged. Otherwise, this indicates the influence of negative factors and the complete exclusion of the drug. De-Nol is unpretentious to storage conditions, but it depends on them which shelf life the drug will have.  

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