Darrow Solution

Darrow solution refers to the preparations of the group of electrolytes, which in medicine are used to restore the water-electrolyte balance in the body. 

[1], [2], [3], [4], [5],

Indications Darrow Solution

The medication is prescribed to replenish fluid in the body during dehydration, especially when there is a violation of acid-base balance on this background and a decrease in the level of potassium in the blood.

Also, the drug is indicated with long-term use of diuretics, when preparing patients for surgery, and also in postoperative periods. 

[6], [7],

Release form

Darrow solution is available in the form of a solution for intravenous administration (droppers). 

Pharmacodynamics

Darrow solution contains an increased amount of potassium and lactate.

In the liver, lactate is converted to bicarbonate, due to which the drug appears alkaline. If the liver function is not violated and the cells are fully provided with oxygen, lactate is one of the main energy sources.

[8],

Pharmacokinetics

Darrow solution when ingested in the bloodstream for a relatively short time is excreted from the body by the kidneys. Metabolization of lactate occurs in the liver.   

[9], [10]

Dosing and administration

Darrow solution is injected into the bloodstream by means of a dropper.

Adult patients are prescribed from 100ml to 2l per day.

Dosage is determined by the attending physician depending on the patient's condition.

Use Darrow Solution during pregnancy

The medication is prescribed to pregnant women only in case of emergency.

Contraindications

Darrow solution is not prescribed with a decrease in the amount of urine released, a high level of potassium, sodium in the blood, violations of acid-base balance in the body, a low level of oxygen in the blood, acute disturbance of the water-electrolyte balance, pulmonary edema, critical forms of gestosis (late toxicosis), the last stages of heart failure. 

[11], [12]

Side effects Darrow Solution

Darrow solution can provoke excessive accumulation of fluid in the body, increased levels of potassium in the blood, impaired cardiac function. 

[13]

Overdose

Darrow solution in elevated doses provokes a violation of the rhythm of the heartbeats. 

[14],

Interactions with other drugs

Darrow solution is not recommended to interfere with other drugs. 

[15], [16], [17], [18], [19]

Storage conditions

Darrow solution should be stored in a place protected from light and moisture. The drug is stored away from small children. The storage temperature is 10-25 ° C.

[20], [21],

Shelf life

Darrow solution is suitable for two years from the date of manufacture. The drug is suitable for use under the condition of proper storage.

[22], [23]