Cytale

The cytogen has a local antiseptic effect (for the most part - bactericidal).

Indications of the citeal

It is used to eliminate or prevent the development of diseases caused by the activity of bacteria that are sensitive to the drug. Use it for certain pathologies, taking into account the concentration of drug substance.

A solution with 0.05%, 0.1% and 0.2% concentration is used to prevent possible infections that occur after surgical procedures. Can be appointed for dental events - with its help dentures are processed. In addition, the medicine is prescribed for therapy with periodontitis and stomatitis, and also for rinsing gums.

The medication is used in the treatment of the epidermis in urology (if it is necessary to penetrate the urethra), and in addition gynecologists and surgery - before the procedure of surgery to avoid possible infection. With gynecological diseases, it is prescribed for the disinfection of the epidermis with mucous membranes before performing some manipulations. The scheme of application of drugs is determined by the type of procedure.

In addition, in gynecology, medication is used to treat thrush - douches are carried out with a solution according to a certain scheme.

The cytogen is prescribed for the treatment of a variety of dermatological pathologies that have a fungal or bacterial origin. In addition, it is used for application to purulent wounds and diseases in the mucous membranes, which appeared due to the influence of microbes sensitive to the action of the active component of the drug.

The medication is also prescribed for the treatment of damaged parts of the epidermis and wounds - to avoid infection.

The cytologist is prescribed to prevent the development of STDs - among them chlamydia, along with herpes, having a genital character, syphilis and trichomoniasis with gonorrhea.

The substance with a 0.5% concentration is applied to get rid of damage arising on the epidermis or mucous membranes, and with it, for disinfecting a variety of medical devices (the liquid temperature regime is 70 ^to C).

1% drug is prescribed to prevent the development of infection in places where there are wounds or burns, and to decontaminate the site of the ongoing operation. Another method of use is for disinfection of different instruments with instruments that can not be subjected to heat-type treatment.

Solutions with a 5% or 20% concentration are used to make medicinal solutions, the main element of which are substances such as glycerin with alcohol or plain water.

[1]

Release form

The drug is produced in the form of a drug solution, which has a different concentration, in polymer bottles with a nozzle, and in addition in glass vials with a capacity of 0.1 liters. Inside the box there is one such bottle. In this case, a 20% solution is released in flasks with a capacity of 0.1 or 0.5 liters.

The medication is also implemented in the form of a gel (containing lidocaine), suppositories, ointments along with cream and spray.

Pharmacodynamics

The drug has a local disinfecting effect, is a 2-chloro-containing derivative of the biguanide component. The mechanism of action occurs by changing the characteristics of the bacterial cell walls. Cations formed by the separation of chlorhexidine salts actively combine with microbial shells that have a negative charge. Activity of drugs helps to destroy the cytoplasmic microbial wall - the destruction of its balance contributes to the final death of the microbe.

The drug exhibits marked activity against many bacterial strains. Among them, bacteroids are fragilis with gonococci, and at the same time vaginal trichomonas with gardnerella vaginalis and pale treponema with chlamydia. The substance affects ureaplasma and moderately affects individual strains of pseudomonads with proteas.

Resistance to drugs demonstrates fungal spores along with viruses (excluding herpes).

The cytogen has a long antibacterial effect in the treatment of the hands and skin surface.

The drug retains its antimicrobial properties in the presence of blood with pus and other liquids, although its effectiveness in these cases is weakened.

[2]

Dosing and administration

Alcohol or aqueous chlorhexidine substances are prescribed to eliminate local infections.

To prevent the possible occurrence of sexually transmitted diseases, you should use LS in a 0.05% therapeutic concentration within 120 minutes after an unprotected coitus occurred. In this situation, a man is recommended to inject 2-3 ml of the substance into the urethra, and a woman 1-2 ml in the same place, plus 5-10 ml in the vaginal area (as in the procedure of gynecological syringing). It is also recommended that the epidermis be treated with the medicament next to the genitals. It is required to refrain from urinating at least 2 hours after drug administration, because otherwise its effectiveness will decrease.

As a preventive measure in such cases, you can use the medicine in the form of suppositories.

With regard to syringing for therapy with thrush and other diseases that have a gynecological origin, as well as the method of this procedure, you must first consult with a gynecologist. When syringing, a 0,05% solution is needed, which does not need additional dilution. Before the syringing session, it is necessary to sit horizontally, introduce a little medicine from the vial into the vagina, and lie down for a few minutes. This is required as a check for the presence of the patient's allergies. If this procedure caused the appearance of negative symptoms, you need to give up syringing.

With inflammation in the area of the urethra, 2-3 ml of 0,05% substance are injected inside the urinary canal (1-2 times per day). This course is conducted for 10 days. This method is suitable for women and men.

When treating wound areas and burns with other injuries of the epidermis, 0.05%, 0.02% or 0.5% substance is used - appliqués or irrigation are performed. The duration of the application is 1-3 minutes. In addition, you can use the Cytele spray.

If you want to disinfect the skin area before the operation, a 20% solution is used, previously diluted with 70% ethanol (here the ratio is 1k40). Process the prepared area twice, with a gap of 120 seconds.

The drug is also used to treat certain ENT diseases (tonsillitis with angina and pharyngitis). For the treatment of sore throat rinsing is performed with a 0.2% or 0.5% solution.

Before performing a rinse with Cytaleal, you should thoroughly rinse your mouth with warm water. After that, take a tablespoon of the substance (10-15 ml) and rinse your throat for about half a minute. These actions can be repeated one more time. After the procedure, it is recommended not to drink or eat during the 60-minute period. More detailed instructions regarding the rinses and frequency of the procedure are determined by the attending physician, taking into account the patient's symptoms. In addition, the doctor should be treated when there are negative reactions to the drug.

The appearance of a burning sensation during the rinsing procedure often indicates that the preparation has too strong a concentration. The maximum allowable concentration is 0.5%.

Rinsing of the oral cavity after the procedure of tooth extraction can be carried out three times a day - for 60 seconds.

Swallow drug can not. In case of unintentional ingestion of the drug, activated charcoal (1 tablet per 10 kg) should be taken.

It is forbidden to carry out the procedures of nasal lavage for the treatment of sinusitis, as the medication taken into the nose can penetrate into the inner ear cavity or the cerebral membrane, which is fraught with the appearance of severe consequences.

[9], [10]

Use of the citeal during pregnancy

Pregnant and nursing mothers are allowed to prescribe Cytale for topical use. However, although pregnant medicine is not strictly prohibited, it is still not advisable to use it for a long time.

Pregnant women can gargle with a drug solely under medical supervision.

Contraindications

Among the contraindications:

• the presence of hypersensitivity relative to the components of drugs;
• presence of dermatitis in the patient;
• combination with other antiseptic medicines (eg, hydrogen peroxide, etc.);
• disinfecting the epidermal area with medicament before performing a surgical procedure on the CNS site or an ear canal or after such intervention;
• use in ophthalmic procedures - it is forbidden to use a substance for washing the eyes, in these cases, specific solutions are used.

[3], [4], [5], [6]

Side effects of the citeal

The use of the drug sometimes causes the development of certain side effects: for example, itching and dryness of the epidermis, and in addition the occurrence of rashes, various dermatitis or photophobia.

Long-term use of the drug for irrigation or mouthwash can lead to a change in the shade of tooth enamel and imbalance of taste buds, and in addition to the appearance of calculus.

[7], [8]

Overdose

It was not reported on the development of intoxication from the use of drugs. If some part of the solution has been taken orally, you should perform a gastric lavage procedure, drink an enterosorbent and eliminate the remaining symptoms.

Interactions with other drugs

At a pH above the digital value of 8, a precipitate is recorded. If you use hard water in the process of manufacturing drugs, its bactericidal performance is reduced.

The cytogen can not be combined with anionic elements (for example, with soap), and in addition with carbonates and chlorides, and at the same time with borates or sulfates, as well as with citrates or phosphates.

The effect of the drug increases the sensitivity of bacteria to the effects of such components as chloramphenicol with neomycin and cephalosporin with kanamycin.

Ethanol increases the bactericidal therapeutic effect of drugs.

[11], [12], [13], [14], [15], [16]

Storage conditions

The cite should be kept in a dry and closed place from sunlight. Temperature - not more than 25 ° C.

Shelf life

Medication with 0,05% concentration is allowed to use within 2 years from the date of release, and with 20% concentration - for 3 years.

Ready therapeutic solutions have a 7-day shelf life.

[17]

Use in children

In children, the medication is used cautiously and exclusively with the appointment of a doctor.

Analogues

Analogues of the drug are medicines Gibiskrab, Geksikon with Geksikon D (for children), Amident and so on.

Reviews

The cytologist receives mostly positive reviews. Both doctors and patients talk about the strong disinfecting effect of the medication. There are positive data on its use in gynecology and dentistry, and also when rinsing the mouth and throat. Negative symptoms are noted only sporadically. A high result is observed in the case of using drugs to eliminate acne.

For skin on the face used 0.01% solution, which has an antimicrobial effect in contact with the skin. But in the reviews warn that before applying the drug for facial treatment should consult a dermatologist.

With proper use, as indicated in the comments on the drug, it effectively copes with pimples. They handle the areas around the pimples on the face. Often, patients write about the fact that you can quickly eliminate acne by combining the Cytale with other medicines.

Shampoo, which contains a 4% solution of drugs, can be used to prevent the occurrence of infections on the skin in cats and dogs (and other pets). The testimonials indicate that it imparts silky wool and perfectly cleanses the skin.