Injections are performed in / m and / in the method (jet or drip) - the choice of the method of administration depends on the chosen dosage, regimen and degree of severity of the pathology.
For adolescents from 12 years (or with a weight of 50+ kg) and adults.
In the case of uncomplicated infectious processes, injections are required at a rate of 1 g at intervals of 12 hours intramuscularly or intravenously.
To eliminate uncomplicated gonorrhea in the acute form requires a single injection of 0.5-1 g intramuscularly. With the development of moderate infections, it is necessary to inject in / in or in / m way in the amount of 1-2 grams at intervals of 8 hours. When the need to administer large doses of antibiotic (for example, with sepsis), injections in the amount of 2 g intravenously with intervals of 6-8 hours are prescribed. If the infectious process acquires a life-threatening form, it is allowed to shorten the intervals between the procedures up to 4 hours (no more than 12 g can be administered per day).
With antimicrobial prophylaxis, in order to prevent the appearance of complications of purulent-septic nature after surgery, injections in the amount of 1 g (once a day, half an hour before the procedure) are used. If necessary, you can repeat the injection after 6 and 12 hours. Patients undergoing cesarean section are required to administer 1 g of the solution intravenously immediately after the umbilical cord has been clamped. Further, if necessary, it is allowed to inject additional injections in the amount of 1 g after 6 and 12 hours after the first dose.
Persons suffering from disorders of renal function in severe form (CC level is 20 ml / minute / 1.73 m 2 ), it is required to reduce the daily dose of drugs by half.
Children at the 1st month of life (without taking into account gestational age) are required to administer such doses of the medicine:
- at week 1, an intravenous injection of 50 mg / kg is necessary at intervals of 12 hours;
- period 1-4 weeks - intravenous injection of 50 mg / kg at intervals of 8 hours.
Children, starting with the 1st month and up to 12 years (or weighing less than 50 kg), the daily dose of the solution (50-180 mg / kg) should be divided into 4-6 injections (intravenously or intramuscularly). If a severe infection (eg, meningitis) is observed, the daily dose for the child should be increased to 200 mg / kg (for 4-6 injections).