Calcium glycerophosphate

Calcium is a key chemical element involved in the biochemical and physiological processes of a living organism. It is involved in the mechanism of blood clotting, muscle contraction, serves as a vehicle for delivering various substances to cell membranes that are necessary for processes occurring in the cell, in particular the synthesis of hormones and neurotransmitters. The need for this macronutrient is different at each age. The greatest is in adolescence (1.3 g per day), since intensive skeletal growth requires more "building material". Calcium enters the body with food: milk, cottage cheese, legumes, nuts, vegetables, there is a lot of it in poppy and sesame. A deficiency of the substance affects the state of health and appearance: irritability, nervousness, fatigue appear, the skin becomes withered, hair is dull and brittle, muscle spasms appear, and sometimes they tremble. The most dangerous is the development of rickets in children and osteoporosis in adults. Calcium glycerophosphate is a remedy for calcium deficiency.

Indications Calcium glycerophosphate

Indications for use are hypocalcemia, dystrophy, rickets in children, as a general tonic and strengthening agent for exhaustion of the nervous system, rapid onset of fatigue.

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Release form

Release form - white tablets containing the main substance - calcium glycerophosphate and a number of auxiliary substances.

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Pharmacodynamics

Calcium glycerophosphate normalizes calcium-phosphorus metabolism, stimulates the process of protein synthesis, and replenishes the mineral deficiency in the body. The pharmacodynamics of the drug is due to the ability of calcium ions to participate in various metabolic processes, which is necessary to maintain the functioning of the cardiac myocardium, in the processes of blood clotting, and the formation of bone tissue.

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Pharmacokinetics

The pharmacokinetics of the drug are as follows: calcium absorption occurs mainly in the duodenum, since there is the highest concentration of calcitriol - a hormone whose biological role in the body is to promote the absorption of calcium and phosphate. This is precisely why there is a subtle mechanism for regulating its production. Lactose also promotes absorption, and a number of fats interfere: cow's milk, beef, palm oil. This natural regulation scheme maintains the content of the substance in the body in balance. It is excreted mainly through the intestines (80%), the rest - through the kidneys.

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Dosing and administration

The method of administration and dosage are as follows: the drug is taken after meals, washed down with liquid. Children are recommended 1 tablet (200 mg) 1-3 times a day, adults - 1-2 pieces (200-400 mg) with a frequency of 2-3 times.

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Use Calcium glycerophosphate during pregnancy

Use during pregnancy is not contraindicated. During lactation, if the child is prescribed calcium or vitamin D3 preparations, the nursing woman should refrain from taking calcium glycerophosphate, otherwise it will lead to an overdose.

Contraindications

Contraindications to the use of the drug exist for people with excess calcium in the blood and urine, allergies to any of its components, serious kidney dysfunction, increased blood clotting, atherosclerosis. Not prescribed to children under 3 years of age.

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Side effects Calcium glycerophosphate

The development of allergies, hypercalcemia and calciuria are possible side effects of calcium glycerophosphate. Nausea, abdominal pain, and disturbances in the defecation system may also occur.

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Overdose

Overdose may cause hypercalcemia (over 2.5 mmol/l in serum), which will manifest itself as nausea, diarrhea or constipation, abdominal pain, and high blood pressure. Such symptoms require discontinuation of the drug and the use of intravenous calcitonin as an antidote.

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Interactions with other drugs

Simultaneous administration of calcium preparations enhances the effect of tetracycline antibiotics and cardiac glycosides - cardiological agents based on plants: foxglove (digitoxin, digoxin), lily of the valley (corglycon), adonis (tincture). Combined use with glucocorticosteroids, loop diuretics reduces the content of the substance in the body, but thiazide diuretics can lead to hypercalcemia.

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Storage conditions

Required storage conditions: original packaging and out of reach of children; the drug does not require any special storage conditions.

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Shelf life

The shelf life is 5 years, after which the packaging should be thrown away.

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