Calcium Citrate

Calcium citrate is a mineral-vitamin complex.

[1], [2], [3], [4], [5]

Indications of the calcium Citrate

It is used in combination therapy and prevention of osteoporosis (idiopathic or steroidal origin or during postmenopause), as well as complications of this disease (with fractures of bones).

To make up for the lack of cholecalciferol and calcium, which developed due to malnutrition.

At a time when the body is in great need of cholecalciferol with calcium: for pregnant and nursing mothers, as well as adolescents from 13 years of age at the stage of intensive growth.

[6], [7], [8]

Release form

The release occurs in tablets, 60 pieces per pack.

[9], [10]

Pharmacodynamics

A complex medicine that stabilizes the processes of metabolism of phosphorus, as well as calcium in the body. Helps to fill the shortage in the body of cholecalciferol with calcium.

Calcium is a participant in the regulatory processes of impulse transmission within the NS, as well as muscle contractions. He enters the system of blood uptake and helps the formation of bone tissue, mineralization of the teeth, and also improves the work of the heart.

Cholecalciferol affects the metabolism of phosphorus with calcium, increases intestinal absorption of calcium, as well as renal reabsorption of phosphorus. In the first pill contains 10-15% of the daily needs of the organism in the element Ca.

[11], [12], [13], [14]

Pharmacokinetics

The medicine is well absorbed inside the digestive tract, and its excretion occurs with feces, as well as urine.

[15], [17], [18], [19]

Dosing and administration

The drug is taken in the amount of 1-2 tablets 2-3 times / day (or assigned an individual mode of use, depending on the clinical picture). It is necessary to swallow the pill and wash it with liquid.

The duration of therapy depends on the severity and nature of the disease. Usually it lasts for 1 month, and subject to the presence of indications, the course can be continued in normal mode after the 1st week of the break. Such interruptions (7-day) should be done after every 4 weeks of therapy.

A day is allowed to take no more than 6 tablets.

[28], [29], [30]

Contraindications

The main contraindications:

• intolerance of the elements of the drug;
• hypercalciuria or hypercalcemia (this includes diseases associated with prolonged immobility and hyperparathyroidism of both primary and secondary type);
• sarcoidosis;
• marked degree of renal failure;
• urolithiasis;
• caused by prolonged immobility of osteoporosis;
• children under the age of 13 years.

[20], [21], [22],

Side effects of the calcium Citrate

Often, the intake of calcium citrate causes hypercalcemia and a disorder in the kidney in the case of long-term use of large doses of drugs. Symptoms of allergies may also be noted. Occasionally manifestations of dyspepsia - diarrhea or constipation, abdominal pain and nausea.

[23], [24], [25], [26], [27]

Overdose

Because of chronic or acute poisoning, the patient may develop hypercalcemia associated with intolerance to cholecalciferol. Toxic effect is observed when consuming more than a hundred tablets per day.

Among the signs: the development of anorexia, vomiting, dizziness, constipation, nausea, myalgia and headaches. Also, heartburn, kidney problems, a sense of weakness, diarrhea, crystalluria and an increase in blood pressure are noted. Loss of consciousness and coma may develop.

With the development of such symptoms, it is necessary to cancel the drug and give the victim plenty of fluids. He also needs to eat food, which contains a minimum of calcium. If there is hypercalcemia to a significant degree, it is required to introduce intravenous infusion of saline, and in addition to administer furosemide and perform the procedure of hemodialysis.

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Interactions with other drugs

Calcium can increase the absorption of tetracyclines, iron drugs and products containing fluoride, which requires the use of calcium citrate at least 3 hours or 3 hours after the application of the above medicines.

In people who take along with the drug diuretics from the category of thiazides, hypercalcemia can develop alone.

The drug weakens the properties of aluminum-containing antacids.

[32], [33], [34],

Storage conditions

Calcium citrate is required to be kept in a dark and dry place, closed from the access of young children. Temperature limits - within the limits of 8-15 ° С.

[35], [36], [37], [38], [39],

Special instructions

Reviews

Calcium citrate is an effective vitamin-mineral complex that helps to fill the deficiency of nutrients inside the body. Judging by the reviews, it helps with pregnancy, and also as a preventative against osteoporosis. Being an effective source of calcium, improves the condition of teeth, hair and nails. It also works well for problems with the joints, making the pain in them more rare and less pronounced.

[40], [41]

Shelf life

Calcium citrate is allowed to be used for 2 years from the date of release.

[42]