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Brucellosis vaccine
Last reviewed: 23.04.2024
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Brucellosis - zoonotic human infectious disease in contact with a sick animal or its secretions, as well as when using infected non-pasteurized milk or dairy products. A vaccine against brucellosis is necessary for professional groups (persons over 18 years old). The goal of vaccination is the prevention of goat-sheep brucellosis.
Brucellosis Vaccine live dry - the lyophilized culture of live bacteria vaccine strain of Brucella Brucella abortus 19 VA, has the form of a homogeneous mass of white or yellowish color. Form release: 1 ml (4-10 doses) in the ampoule. Packing - 5 ampoules. Shelf life 3 years. Store and transport at a temperature of up to 8 °.
[Method of application and dosage of the vaccine against brucellosis
The vaccine against brucellosis is carried out no later than 3-4 weeks before the start of work associated with the risk of infection (the time of development of immunity), the maximum of tension lasts 5-6 months, duration - 10-12 months. Before vaccination, the specific immunity of one of the serological or skin-allergic reactions is determined. Only persons with a negative reaction should be vaccinated.
Vaccination is carried out in the area of the outer surface of the shoulder at the border between the upper and middle third, once dermally or subcutaneously. A single dose with a dermal administration is 2 drops and contains 1-10 10 microbial cells, with subcutaneous administration - 0.5 ml and contains 4-10 8 microbial cells. Revaccination is carried out after 10-12 months. Cutaneous, using a half dose (5-10 9 ). A diluted vaccine, preserved with aseptic rules, can be used for 2 hours.
Simultaneous dermal vaccination against brucellosis and vaccination against one of the following infections is allowed: Ku ricquetsiosis, tularemia and plague.
Cumulative vaccination is carried out through 2 drops of vaccine applied at a distance of 30-40 mm from each other; the vaccine is diluted at the rate of 0.1 ml of saline solution per 1 inoculum dose. Make 6 incisions (3 longitudinal and 3 transverse) 10 mm each with a distance of 3 mm between them, the vaccine is rubbed for 30 seconds and allowed to dry for 5 minutes. When revaccination, 1 drop is made with 6 incisions.
Subcutaneous vaccination: the vaccine dose is 25 times less; the vaccine is diluted at the rate of 12.5 ml of saline for 1 dose of the vaccine for dermal application. The vaccine against brucellosis is injected in a volume of 0.5 ml.
Reactions to administration and contraindications to the vaccination against brucellosis
The reactions to the introduction of the vaccine against brucellosis are usually insignificant. Local reaction with cutaneous vaccination can appear in 24-48 hours in the form of hyperemia, infiltration or pink-red nodules along the incisions. With subcutaneous injection after 12-24 hours at the injection site, hyperemia, infiltration up to a diameter of 25 mm, and mild soreness may appear. The general reaction occurs in the first day in 1-2% of the vaccinated and is expressed by malaise, headache, fever to 37.5-38 °.
In addition to the common for all vaccinations, contraindications are:
- Brucellosis and brucellosis in children in a history, a positive serological or skin-allergic reaction to brucellosis.
- Systemic diseases of connective tissue.
- Common relapsing of skin diseases.
- Allergic diseases (bronchial asthma, anaphylactic shock, Quincke's edema) in the anamnesis.
Attention!
To simplify the perception of information, this instruction for use of the drug "Brucellosis vaccine" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.