Bioparox for sore throat

Antibiotics are often used to treat tonsillitis. One of these drugs is Bioparox. Let's consider the features of this medication and the rules for its use.

Angina is an acute infectious disease that occurs with viral damage to the components of the lymphatic pharyngeal ring - tonsils. It is one of the most common pathologies of the upper respiratory tract.

• In 85% of cases, the disease is associated with streptococcal infection; pneumococcus, staphylococcus, or mixed microflora are less common.

• Tonsillitis resembles a cold in its symptoms, but is much more difficult to bear. The body temperature rises to 39 °C, acute pain in the throat occurs, which intensifies when swallowing and eating food. The lymph nodes enlarge, the tonsils and soft palate are hyperemic.

The danger of tonsillitis is not only in its acute course and painful symptoms, but also in the fact that the patient is a carrier of pathogenic microorganisms. Bacteria are released into the environment during coughing or talking. Timely treatment allows you to effectively eliminate the disease and prevent its complications, as well as reduce the risk of infecting others.

Treatment should be comprehensive. Patients are prescribed a course of medications, local treatment of the inflamed throat, diet and physiotherapy. Particular attention is paid to antibacterial therapy, the action of which is aimed at destroying pathogenic flora.

For local treatment of infectious and inflammatory diseases, it is best to use inhalation drugs such as Bioparox. It belongs to the pharmacological group of polypeptide antibiotics. Contains the active substance - fusafungin, isolated from the culture of the fungus Fusarium lateritium. It has anti-inflammatory and bacteriostatic properties against a wide range of bacteria and fungi.

Indications Bioparox for sore throat

Bioparox is prescribed for local action on the inflammation site. Active components are distributed in the oral cavity and nasopharynx, destroying pathogenic microorganisms. The main indications for its use are acute inflammatory diseases of the ENT organs and upper respiratory tract.

The medicine is used in the following cases:

• Tonsillitis.
• Tracheitis.
• Bronchitis.
• Laryngitis.
• Rhinopharyngitis.
• Rhinitis.
• Sinusitis.
• Pharyngitis.

Bioparox is also suitable for the prevention of infectious complications after tonsillectomy.

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Bioparox for purulent tonsillitis

It is the purulent form of tonsillitis that causes the greatest concern. The most effective treatment method is antibacterial drugs that act directly on the affected tissues. Bioparox is used locally. The aerosol irrigates the inflamed mucous membranes, destroys pathogenic microorganisms, preventing complications of the disease.

If systemic antibiotics are used to treat purulent tonsillitis, Bioparox is not prescribed. It should be taken into account that the drug is most effective in treating early stages of tonsillitis.

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Release form

The antibacterial agent is available in the form of an aerosol for local use. The drug is available in 20 ml aluminum cans. The drug comes with two spray nozzles. One can is designed for 400 doses.

Pharmacodynamics

Bioparox has bacteriostatic and fungistatic properties. Its active components are embedded in the bacterial cell membrane, disrupting its functioning. This leads to the loss of the ability of pathogenic microorganisms to reproduce, migrate, adhere and produce exotoxins.

The antibiotic is sensitive to the following pathogens:

• Gram-positive and Gram-negative aerobic bacteria: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus spp. (including Streptococcus pneumoniae, Streptococcus group A, B, C, G), Moraxella catarrhalis, Listeria monocytogenes, Corynebacterium pyogenes, Pasteurella multocida, Bacillus subtilis and some strains of Neisseria spp.
• Anaerobic bacteria: Propionibacterium acnes, Clostridium butyricum, Clostridium perfringens and Streptococcus mutans.
• Mycoplasma spp., actinomycetes and fungi of the genus Candida.

The drug also has anti-inflammatory properties. It inhibits the synthesis of proinflammatory cytokines, reducing swelling of affected tissues. The drug does not exhibit cross-resistance with systemic antibiotics.

Pharmacokinetics

When inhaled, fusafungine is not absorbed into the systemic bloodstream, but accumulates on the mucous membrane of the oropharynx and nose. A small amount of the active substance can be found in the blood plasma. But this is absolutely safe for the body, since the maximum plasma concentration does not exceed 1 ng / ml.

After administration of 3-4 doses through the oral cavity, different concentrations of fusafungine are created in the respiratory tract:

• On the mucous membrane of the lungs – 80 mcg/ml.
• On the mucous membrane of the trachea and bronchi – 40 mcg/ml.
• On the mucous membrane of the nasal cavity – 60 mcg/ml.

If the drug is administered through the nose, the maximum concentration of the active component in the mucus is observed after three hours and is 2000 mcg/l. The drug is excreted from the body with respiratory secretions.

Dosing and administration

Bioparox for tonsillitis is used for inhalation through the mouth. The dosage of the drug and the course of treatment depend on the severity of tonsillitis, so they are determined by the doctor individually for each patient.

• Patients over 12 years of age are prescribed 4 doses orally 3-4 times a day.
• For children from 2.5 to 12 years old – 2-4 injections 3-4 times a day.

The canister with the preparation should be shaken well and pressed a couple of times, then put on the white nozzle. The aerosol is held vertically, tightly clamping the nozzle inserted into the oral cavity with the lips. When inhaling, press on the base of the canister and hold your breath for a couple of seconds for better irrigation of the trachea and bronchi.

The duration of therapy should not exceed 7 days. The nozzles used should be disinfected daily with an ethyl alcohol solution or other disinfectant.

Bioparox for sore throat in adults

Tonsillitis in adults is as common as in children. The disease is most often associated with staphylococci, streptococci or other pathogenic microorganisms. Symptoms appear when exposed to the following factors:

• Decreased general or local immunity.
• Hypothermia.
• Tonsil injuries.
• Respiratory failure.
• Chronic inflammatory processes in the nose, oral cavity, paranasal sinuses.

Since the disease is infectious in nature, antibacterial, antimicrobial and other drugs are used for treatment, which alleviate the course of the disease and destroy its pathogens.

Bioparox for angina in adults fights pathogenic microorganisms, stops the inflammatory process, relieves swelling of the affected tissues, improving breathing. The aerosol is used for inhalation through the mouth. The medicine is administered 4 doses 3-4 times a day for 7 days. The antibiotic can only be used as prescribed by the attending physician.

Bioparox for sore throat in children

Treatment of tonsillitis in children should be comprehensive. Babies are prescribed the safest and at the same time effective drugs. An obligatory component of therapy is antibiotics, the action of which is aimed at destroying pathogenic microorganisms.

For children over 2.5 years old, Bioparox is prescribed. The drug is a polypeptide antibacterial agent for local use. Its active components act directly on the lesion. The aerosol is injected orally in 3-4 doses up to 4 times a day. The duration of treatment should not exceed 5-7 days.

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Use Bioparox for sore throat during pregnancy

A medicinal product with anti-inflammatory and antibacterial properties. The active components of the aerosol are not absorbed into the bloodstream and do not have a systemic effect. Because of this, some doctors consider the drug safe during pregnancy. However, clinical studies of Bioparox have not been conducted on pregnant women, so there is no absolute certainty that the drug is safe for the fetus.

The use of an inhaler for the treatment of sore throat is possible in cases where the expected benefit to the mother is higher than the potential harm to the fetus. In this case, the high risks of developing bronchospasms due to the injection of the drug into the pharynx are taken into account. Also, the antibiotic is not recommended during lactation. When it is prescribed, breastfeeding should be discontinued.

Contraindications

The main contraindication to Bioparox is hypersensitivity to its components. The drug is also not prescribed in the following cases:

• Patients under 2.5 years of age due to high risk of developing laryngospasm.
• Tendency to allergic reactions.
• Tendency to bronchospasms.

During treatment, do not allow the aerosol to come into contact with the eyes. If this happens, immediately rinse the eyes with plenty of clean running water and seek medical attention.

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Side effects Bioparox for sore throat

Bioparox is well tolerated by patients, but in some cases side effects occur:

• Respiratory system and ENT organs: dry mucous membranes of the nose and throat, burning in the throat, sneezing, spasms, difficulty breathing, laryngospasms.
• Gastrointestinal tract: nausea, vomiting.
• Sense organs: unpleasant taste in the mouth, lacrimation, redness of the eyes.
• Allergic reactions: skin rash, itching, urticaria, anaphylactic shock.

If the above symptoms appear, stop taking the medicine and consult your doctor. If the aerosol has caused anaphylactic shock, then intramuscular injection of adrenaline 0.01 mg/kg is indicated, if necessary, the injection is repeated after 15-20 minutes. When using this antibiotic for more than 7 days, there is a risk of developing a superinfection.

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Overdose

Exceeding the dosage prescribed by the doctor or treatment for more than 7 days leads to the development of adverse symptoms in many organs and systems. Overdose is manifested by circulatory disorders of varying severity. Most often, patients experience:

• Tachycardia.
• Feeling of numbness in the mouth.
• Headaches and dizziness.
• Increased pain and burning sensation in the throat.

Treatment is symptomatic with discontinuation of the drug and mandatory medical consultation.

Interactions with other drugs

Since Bioparox is applied locally, its interaction with systemic drugs is permissible: oral and injection forms.

The antibiotic is contraindicated to be combined with any alcohol-containing medications or drinks. Since a chemical reaction of its molecules with ethanol occurs, which leads to the accumulation of a toxic substance in the body - acetaldehyde.

Intoxication manifests itself in headaches, rapid breathing, convulsions, and heart rhythm disturbances. All drug interactions must be approved by the attending physician.

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Storage conditions

The aerosol antibiotic canister should be stored in a dry place, protected from direct sunlight and out of reach of children. The medicine should not be exposed to high temperatures. The optimal storage temperature is 22-25 °C.

Shelf life

According to the instructions for use, Bioparox must be used within 24 months from the date of its production, which is indicated on the packaging and the aerosol can. Expired medication should be disposed of. Empty cans must not be heated or punctured.

Reviews

The drug Bioparox, prescribed for the treatment of tonsillitis, has proven itself in the treatment of both adults and children. Reviews of its use are varied. Many patients note that in the early stages of tonsillitis, the antibiotic quickly stops the inflammatory process and accelerates recovery. While in more severe cases of infectious disease, monotherapy with Bioparox is not effective. The drug is approved for use as an over-the-counter drug, but before using it, you should consult with your doctor.