Becotide Evohaler

Becotide Evohaler is an anti-asthmatic drug for inhalation. Let's consider the conditions of its use: indications, dosage, side effects, storage conditions.

An inhaler is the best way to relieve asthma attacks because it delivers medications directly to the bronchial system. An asthma attack is a dangerous condition that requires emergency treatment. Tablets, syrups, injections, and other forms of medication do not have an immediate effect, unlike inhalations.

Another advantage of the inhaler is its ease of use and safety. It is suitable for treating asthma attacks in patients of any age. Becotide Evohaler is classified as a hormonal drug, as its active ingredient is a glucocorticosteroid. It reduces inflammation in the body and relieves swelling of the mucous membranes, making breathing easier.

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Indications Becotide Evohaler

The main indication for the use of Becotide is the basic treatment of bronchial asthma in adult and pediatric patients. The drug is prescribed for:

• Recurrent asthma attacks
• Treatment and prevention of bronchospasms
• Chronic asthma

The inhaler is suitable for relieving mild, moderate and severe asthma attacks.

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Release form

Becotide Evohaler is available as an inhaler. Each aerosol dose contains beclomethasone dipropionate 50 mcg. The auxiliary components are: HFA 134a, ethanol and glycerin. One canister is enough for 100 doses-injections.

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Pharmacodynamics

The active substance of the drug is beclomethasone dipropionate, which is a precursor of the active component similar to glucocorticosteroid receptors. Pharmacodynamics indicate hydrolysis by esterases with the formation of a metabolite - beclomethasone-17-monopropionate. The resulting substance has local anti-inflammatory activity.

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Pharmacokinetics

Becotide is used for inhalation. Pharmacokinetics shows low systemic absorption of the dose passing through the lungs and entering the digestive tract. During absorption, the active ingredient is converted into an active metabolite. Its systemic absorption consists of absorption in the gastrointestinal tract and lungs. Bioavailability of inhalation use is 60%.

Beclomethasone dipropionate is rapidly eliminated from the systemic circulation. The volume of distribution and plasma protein binding are moderately high. The drug has high clearance, the half-life is from 30 to 90 minutes. 60% of the dose taken is excreted in feces, 12% in urine. Renal clearance is insignificant.

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Dosing and administration

This anti-asthmatic drug is administered by inhalation. Doses of Becotide depend on the severity of pathological symptoms and individual response to the drug. For mild asthma, 200-600 mcg, for moderate asthma, 600-1000 mcg, and for severe asthma, 1000-2000 mcg per day in proportional doses.

If the medicine is used to prevent asthma attacks, it should be used on a regular basis, even in the absence of attacks. When treating children, a spacer attachment can be used to facilitate inhalation of the inhalation agent. It is necessary to stop using the drug gradually, this will help to avoid side effects of glucocorticosteroids.

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Use Becotide Evohaler during pregnancy

The safety of Becotide use during pregnancy has not been established. The possibility of use is determined by the expected benefit to the mother taking into account the potential risks to the fetus. The active substance is excreted in small quantities in breast milk, so the inhaler is not recommended for breastfeeding.

Contraindications

The Becotide inhaler is contraindicated for use in case of intolerance to the components included in its composition. The drug is not prescribed for bleeding in the lungs, hemoptysis, cardiovascular diseases, severe hypertension, hematopoiesis disorders and pulmonary emphysema.

Inhalations are not recommended in the post-stroke or post-infarction period, as well as at elevated temperatures. The drug is prescribed with special caution to patients with latent or active pulmonary tuberculosis.

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Side effects Becotide Evohaler

Incorrect use of the drug causes side effects. Becotide can cause the following reactions:

• Candidiasis of the oral cavity and pharynx.
• Skin allergic reactions (burning, itching, hyperemia).
• Swelling of the oropharynx, eyes, face.
• Respiratory and anaphylactic reactions.
• Adrenal suppression.
• Glaucoma and cataracts.
• Growth retardation in children and adolescents.
• Sleep disturbances and increased anxiety.
• Throat irritation and hoarseness.
• Paradoxical bronchospasm (occurs extremely rarely).

To eliminate the above-described reactions, symptomatic therapy is indicated.

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Overdose

The use of high doses causes adverse symptoms. Overdose of Becotide manifests itself as temporary suppression of the adrenal cortex function. This condition does not require emergency care, since the body will recover within a few days, which is confirmed by the level of cortisol in the blood plasma.

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Interactions with other drugs

Becotide Evohaler contains ethanol, so when interacting with other drugs, it is necessary to take into account the possibility of developing hypersensitivity reactions. The drug is not recommended for use simultaneously with Metronidazole or Disulfiram.

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Storage conditions

The aerosol can for inhalation should be kept away from direct sunlight and out of reach of children. Storage conditions require maintaining a temperature regime not exceeding 30°C. The drug is prohibited to freeze and keep near open fire.

To prevent premature deterioration, after each inhalation the canister must be tightly closed with a lid and stored in the original packaging.

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Shelf life

Becotide Evohaler must be used within 24 months from the date of manufacture. The expiration date is indicated on the packaging and the aerosol can. After its expiration, the medicine must be disposed of. The used inhaler must not be thrown into a fire or broken.

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