Bactiflox-Lactab.

Baktiflox-LAKTAB is an antibacterial agent that belongs to the group of quinolones. Let's consider the features of the drug, method of application, dosage, possible side effects and contraindications.

Baktiflox-LAKTAB has the international name ciprofloxacin. The medicine is available in tablets, one tablet contains 291.5 mg - ciproflox tin hydrochloride - the active substance of the tablets. Also, the composition of the medicine includes silicon dioxide, microcrystalline cellulose, magnesium stearate, crospovidone and other excipients.

Indications Bactiflox-Lactaba.

Indications for use are based on the action of the active substance of the drug. Baktiflox-LAKTAB is used to treat infectious diseases caused by sensitive strains of gram-positive bacteria. The drug is used to treat infections of the lower and upper respiratory tract, diseases of the genitals and urinary tract. The drug helps in the treatment of infectious diarrhea, lesions of the gastrointestinal tract and oral cavity.

Baktiflox-LAKTAB is used to treat infections of the joints, soft tissues and mucous membrane of the eyes. The antibacterial agent can be prescribed for the prevention of infectious diseases in patients with reduced immunity. The drug is active against pathogenic anthrax caused by Bacillus anthracis bacteria.

Release form

Release form - film-coated tablets of white color. The tablets have a round biconvex shape, with a break line on one side. The active substance of the drug is ciproflox tin hydrochloride. The medicine is available in two dosages Baktiflox 250 and 500, which contain 250 and 500 mg of the active substance.

This form of drug release has its advantages. Easy swallowing of tablets protects against the sensation of unpleasant taste and bitterness, practically does not cause irritation on the sensitive mucous membrane of the stomach. The drug is released in cardboard packages, in one package one blister of antibacterial agent for 10 tablets. Depending on the disease, the necessary dosage of Baktiflox-LAKTAB for treatment and the duration of treatment are selected individually for each patient.

Pharmacodynamics

Pharmacodynamics of Baktiflox-LAKTAB allows you to learn about the processes that occur with the drug after use and how the active substance of the antibacterial agent copes with infectious diseases. Ciproflox belongs to the dofluoroquinolone group and acts as a synthetic bactericidal agent with a wide spectrum of action. The drug is intended for oral use and is active against gram-negative and gram-positive microorganisms.

The peculiarity of the active substance Baktiflox-LAKTAB is that it has resistance to other antibiotics, except for medicinal groups belonging to the quinolone group. The medicine is active against the following microorganisms: Acinetobacter, Branhamella, Brucella, Citrobacter, Corynebacterium, Enterobacter, Plesiomonas, Salmonella, Serratia, Streptococus agalactiae, Staphyloccocus. Alcaligenes, Gardnerella, Mycobacterium fortuitum, Streptococus faecalis and pyogenes, Streptococcus viridans, Treponemapallidum.

Pharmacokinetics

Pharmacokinetics of Baktiflox-LAKTAB is the processes of absorption, absorption, distribution, metabolism and excretion of the drug. The antibacterial agent is perfectly absorbed, the bioavailability of the drug is about 70%. The maximum concentration of Baktiflox-LAKTAB in the blood is observed 1-2 hours after administration. Binding to blood proteins is at the level of 30%, and the average concentration of the active substance in the blood is observed 10-12 hours after administration.

The half-life of the drug in patients with normal renal function is about 4-6 hours. At the same time, 50% of the dose taken is excreted unchanged in the urine. Patients with kidney disease should take half the dose of the drug and increase the time between doses of the antibacterial agent. Please note that the drug is recommended to be taken before meals, otherwise absorption will be slowed by 1.5-2 hours, but this will not affect the overall absorption of the drug and its medicinal properties.

Dosing and administration

The method of administration and dosage of the drug are prescribed individually for each patient and depend on the infectious disease to be treated, symptoms and the presence of contraindications to taking Baktiflox-LAKTAB. Let's consider the standard dosage for infectious diseases that this antibacterial drug treats.

• Infectious lesions of the urinary tract (depending on severity) – 125-250 mg, twice a day.
• Upper and respiratory tract infections – 250 mg twice daily.
• Severe infectious diseases (osteomyelitis and others) – 750 mg of the drug twice a day.
• For threatening infections in patients with cystic fibrosis, peritonitis or pneumonia - 750 mg, up to twice a day.

The duration of treatment with Baktiflox-LAKTAB should not exceed 14 days (60 days in case of particularly severe infectious lesions).

Use Bactiflox-Lactaba. during pregnancy

The use of Baktiflox-LAKTAB during pregnancy is prohibited. Any antibacterial and medicinal preparations are prohibited. If a woman decides to take the medicine, she must understand that the drug can cause the development of pathologies and deviations in her future baby.

Women who take antibacterial and anti-inflammatory drugs in the first trimester of pregnancy fall into the risk category. The risk category means a high probability of genetic and chromosomal abnormalities in the fetus. If urgent treatment of infectious diseases is necessary, doctors select the safest drugs and analogues of Baktiflox-LAKTAB for the pregnant woman.

Contraindications

Contraindications to the use of Baktiflox-LAKTAB are based on individual intolerance to the active substance of the drug. Ciprofloxacin is not recommended for use in patients with hypersensitivity to quinolone antimicrobial drugs.

Baktiflox-LAKTAB is prohibited during pregnancy and lactation. The antibacterial agent is not prescribed to children and adolescents under 18 years of age, since the growth phase is not complete. In any case, the use of the drug should be recommended by the attending physician and correspond to medical indications.

Side effects Bactiflox-Lactaba.

Side effects occur due to non-compliance with the dosage of the drug or long-term use. Side effects of the body to the drug occur extremely rarely, but if they do appear, then, as a rule, these are: vomiting, abdominal pain, diarrhea, headache, flatulence, loss of appetite and indigestion.

In some patients, taking Baktiflox-LAKTAB may cause hypotension, increased heart rate, allergic skin rashes or muscle pain. If side effects of the drug occur, it is recommended to reduce the dose of the antibacterial agent and seek medical help.

Overdose

Overdose may occur due to prolonged treatment, use of an increased dosage, or use of a medicine that has been stored incorrectly or has expired. In case of overdose, toxic kidney damage (reversible) and symptoms that manifest as side effects of the antibacterial agent may be observed.

To avoid overdose, Baktiflox-LAKTAB is prescribed with special caution to elderly patients, people with central nervous system disorders, a tendency to spasms and epileptic seizures. Do not forget that the reactions of the central nervous system to the drug are individual for each patient. One of the side effects of Baktiflox-LAKTAB is the impact on the ability to control mechanisms and vehicles. Therefore, when treating with this antibacterial agent, it is recommended to follow all the rules prescribed in the instructions for the drug.

Interactions with other drugs

Interactions with other drugs are possible only on medical advice and with the permission of the attending physician. The drug is not recommended to be taken simultaneously with antacids that contain aluminum or magnesium hydroxide, since such interaction reduces the bioavailability of ciproflox by 90%. Therefore, it is recommended to take the drugs at intervals of 4 hours.

The same effect is observed when Baktiflox-LAKTAB interacts with aluminum-containing sucralfates. When using this antibacterial agent with theophylline, an increase in the level of the latter in the blood serum is observed, which leads to negative reactions from the central nervous system.

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Storage conditions

The storage conditions are specified in the instructions and correspond to the storage conditions of antibacterial and anti-inflammatory agents. The tablets must be stored in a dry, cool place, inaccessible to children and protected from sunlight. The storage temperature should not exceed 30°C.

If the storage conditions of Baktiflox-LAKTAB are not observed, the medicine loses its medicinal properties. In addition, the medicine loses its physical properties, the tablets may change color or begin to crumble. In this case, Baktiflox-LAKTAB must be disposed of.

Shelf life

The shelf life of Baktiflox-LAKTAB is five years from the production date, which is indicated on the drug packaging. One of the rules for maintaining such a long shelf life of an antibacterial agent is compliance with its storage conditions. After the expiration date, the drug is prohibited from being taken, as this may cause uncontrolled side effects from the gastrointestinal tract and central nervous system.