Bactyl

Baktilem is an antimicrobial drug that belongs to the second generation cephalosporins. Let's consider the main indications for the drug, dosage, contraindications and side effects. Baktilem is a drug whose effectiveness lies in inhibiting the synthesis of harmful microorganisms, which leads to their death and destruction.

Indications Bactyl

Indications for use of Baktilem are based on the action of the active substance of the drug. Baktilem is prescribed for the treatment of infectious diseases and the suppression of harmful microorganisms that are sensitive to the action of cefuroxime.

Baktilem is prescribed for infectious diseases of the respiratory system, bronchi, lungs and ENT organs. The drug helps in the treatment of infectious lesions of the urogenital tract. The drug is active in infectious lesions of soft tissues and skin. The antimicrobial agent is effective against Lyme disease (lesion of the skin and nerve endings by infectious microorganisms).

[ 1 ]

Release form

Release form Baktilem - tablets. The drug is available in a dosage of 250 and 500 mg of the active substance. The tablets are sold in strip packaging, each package contains a plate with Baktilem tablets. The active substance of the drug is cefuroxime axetil. Excipients of the drug: sodium lauryl sulfate, Magnesium stearate, Cellulose microcristallic, sodium croscarmellose and others.

The tablet form of Baktilem allows you to calculate the course of treatment. And the ability to choose the appropriate dosage of 250 and 500 mg of cefuroxime makes it possible to choose the most effective and fastest way to treat an infectious lesion.

Pharmacodynamics

Pharmacodynamics of Baktilem are biochemical effects that occur with the drug after administration. The active substance of the drug is cefuroxime. Cefuroxime is an oral form of a cephalosporin antibiotic with bactericidal action. The drug is active against beta-lactamases, gram-positive and gram-negative microorganisms.

The drug is active against gram-negative and gram-positive aerobes and anaerobes. The drug works by inhibiting the synthesis of the drug. Baktilem is not active against: Clostridium difficile, Campylobacter spp., Acinetobacter calcoaceticus, Legionella spp., Morganella morganii, Enterobacter spp., Citrobacter spp., Bacteroides fragilis.

Pharmacokinetics

Pharmacokinetics of Baktilem are the processes that occur with the drug in the human body. Cefuroxime is absorbed in the gastrointestinal tract and hydrolyzed on the intestinal mucosa. After absorption, the drug enters the circulatory system. The drug is recommended to be taken 30 minutes after a meal, since this is when the maximum absorption level is observed.

The maximum level of Baktilem in the blood serum is observed three hours after administration. Binding to blood proteins is at the level of 35%, and the half-life is 1.5 hours. The drug is excreted by the kidneys. The level of the active substance in the blood serum decreases due to dialysis.

Dosing and administration

The method of administration and dosage of Baktilem are individual for each patient, therefore they are selected by a doctor. The dosage depends on the patient's age, the disease to be treated and the symptoms that appear. The drug is taken orally, after meals. This method of administration ensures good absorption of the drug. The course of treatment with Baktilem should not exceed ten days.

• For infectious diseases in adults, it is recommended to take 250 mg of the drug twice a day. For lesions of the genitourinary system, 125 mg twice a day. For inflammation of the bronchopulmonary system, 500 mg of Baktilem is prescribed twice a day for 20 days. It is recommended to take the drug consistently, gradually increasing the dosage of the drug.
• For infectious diseases in children, Baktilem is taken at 125 mg twice a day, with the maximum available dosage being 250 mg. For the treatment of otitis and severe infections, Baktilem is taken at 250 mg twice a day, with the maximum available dose of the drug being 500 mg.

[ 2 ]

Use Bactyl during pregnancy

The use of Baktil during pregnancy is possible only for medical reasons, when the therapeutic benefit for the mother is much more important than the potential risk to the normal, full development of the child.

The drug is contraindicated for use in the first trimester of pregnancy. This is due to the fact that all vital organs of the baby are formed in the first months of pregnancy. If the drug is prescribed for use in the second and third trimesters of pregnancy, then the woman is required to be especially careful. Baktilem is not recommended for use during breastfeeding, as the drug penetrates into the mother's milk.

Contraindications

Contraindications to the use of Baktilem are based on hypersensitivity to the active substance of the drug. With special caution, the drug is prescribed to patients with impaired renal function, gastrointestinal tract and exhaustion. The drug is prohibited for children under three years of age in tablet form. With long-term treatment, Baktilem causes the growth and development of insensitive flora (enterococci, candida).

If the drug is taken by patients with weakened immunity, diarrhea may develop. Please note that when taking Baktil, it is prohibited to operate machinery and vehicles, as the drug causes severe headaches, dizziness and even hallucinations.

Side effects Bactyl

Side effects of Baktilem are possible if the drug is used by patients who have contraindications to its use. Side symptoms may also appear if the dosage of the drug is not followed or due to exceeding the recommended treatment period. In case of increased sensitivity to the active substance of Baktilem, patients begin to have allergic reactions, urticaria, itching, toxic erythema. In this case, it is necessary to stop using the drug.

In case of dyspeptic side effects, pseudomembranous colitis, elevated liver enzymes and stool disorders, the use of Baktil should be discontinued. Very often, the side effects of Baktil are manifested in the form of headache, decreased levels of leukocytes and platelets, dizziness, apathy.

Overdose

An overdose of Baktil occurs in patients who have exceeded the recommended dosage of the drug. In this case, patients experience neurological changes that are accompanied by seizures. Anticonvulsants are used to treat this overdose symptom.

An overdose of Baktil may also occur during long-term treatment with the drug. In severe cases of overdose, peritoneal hemodialysis is performed to effectively provide assistance to patients.

Interactions with other drugs

Interaction of Baktil with other drugs is possible only if the drug is included in complex treatment and the attending physician has approved the simultaneous use of several drugs. If Baktil is taken with drugs that suppress the secretion of gastric juice, the efficiency of Baktil absorption is reduced.

Please note that if a glucose oxidase test for blood sugar is performed while using Baktil, false positive reactions are possible. When the drug interacts with anti-gout medications, such as probenecid, the level of cefuroxime in the blood of patients increases by 50% of the initial value. In this case, patients experience severe symptoms of overdose and poisoning with the drug.

[ 3 ], [ 4 ]

Storage conditions

Storage conditions for Baktilem correspond to the storage conditions for medicinal products in tablet form. Baktilem should be stored in a dry place, protected from sunlight and out of reach of children. The storage temperature of the drug should not exceed 25°C. Baktilem should be stored only in the original packaging and avoid storing the drug in a damp room.

If the storage conditions for Baktilem are not met, the drug loses its medicinal properties and may cause side effects and overdose symptoms.

Shelf life

The shelf life of Baktilem is two years from the date of manufacture of the drug, which is indicated on the packaging of the drug. After the expiration date, Baktilem must be disposed of. Taking a drug with an expired shelf life or a drug whose conditions were not met is strictly contraindicated.