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B-complex, multi-tabs
Last reviewed: 19.10.2021
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B-complex, multi-tabs B-complex is a multivitamin preparation containing in its composition the main vitamins of group B: thiamin (vitamin B1), riboflavin (vitamin B2), pyridoxine (vitamin B6), cyanocobalamin (vitamin B12 ), pantothenic acid (vitamin B5), folic acid (vitamin B9), as well as nicotinamide (vitamin PP).
Indications B-complex, multi-tabs
B-complex, multi-tabs is recommended for use in the complex therapy of functional disorders of the nervous system and vegetative neuroses, as well as diseases for which this group of vitamins is needed, namely: diabetic polyneuropathy, neuritis, polyneuritis, neuralgia, sciatica, myasthenia, asthenia, dermatitis and neurodermatitis, furunculosis, atherosclerosis, anemia.
Use of B-complex, multi tabs during pregnancy and lactation is allowed. The recommended dosage is 1 tablet 1-3 times a day. During the reception of the B-complex, multiple tabs, it is necessary to exclude the appointment of other drugs containing B vitamins.
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Release form
Product: coated tablets of 60-100 pieces in a plastic jar, packed in a cardboard box.
Pharmacodynamics
The therapeutic effect of this drug is based on the action of its constituent vitamins. Vitamin B1 is involved in the metabolism of fatty acids and carbohydrates, as well as in the synthesis of the neurotransmitter acetylcholine and neurotransmitters (biochemical signal transmitters between neurons).
With the participation of vitamin B6, hemoglobin is formed, neurotransmitters, pyridoxine positively affects the liver and nerve fibers, and also activates folic acid. Flavin enzymes of vitamin B2 are necessary for the formation of erythrocytes, antibodies, for the regulation of growth and reproductive functions of the body. Vitamin B12 also participates in the synthesis of nucleic acids, in the process of formation of blood erythrocytes, epithelial cells and enveloping nerve fibers of myelin.
Vitamin B5 is absorbed into the blood and then into the tissue where biosynthesis of coenzyme forms of pantothenic acid takes place, including coenzyme-A, which participates in lipid metabolism and the formation of antibodies and hormones. Nicotinamide is involved in the metabolism of fats, proteins, amino acids, purines, tissue respiration and promotes carbohydrate metabolism in the body.
Vitamin B9 (folic acid) stimulates the formation of erythrocytes in the bone marrow (erythropoiesis), is involved in the synthesis of amino acids and nucleic acids and the exchange of choline (vitamin B4), as well as in the formation of purine bases and thymidine monophosphate - that is, it provides DNA synthesis. And during pregnancy protects the body from the effects of teratogenic factors.
Pharmacokinetics
Once in the body, some of the active substances of the drug B-complex, multi tabs are distributed in cells of various tissues or blood plasma. Metabolism of vitamins B1 and B6 occurs mainly in the liver, metabolites are excreted in the urine and bile. Vitamin B2 is excreted in the urine or in the form of riboflavin-5-phosphate, or unchanged.
Vitamin B5 is hydrolyzed into the metabolites of pantetine and 3-alanine, which are excreted in the urine. Vitamin B12 is absorbed mainly in the ileum, from there it enters the blood, is deposited in the liver, and its metabolites are excreted with bile. Nicotinamide is metabolized, but part of it is excreted in the urine unchanged.
Folic acid is completely absorbed in the duodenum and small intestine and after 3-6 hours 98.5% of the administered dose is determined in the blood. Deposition and metabolism of folic acid is carried out in the liver, metabolites are excreted from the body with urine and with feces.
Use B-complex, multi-tabs during pregnancy
Before taking the B-complex, multi tabs during pregnancy, it is necessary to consult a doctor.
Contraindications
Among the contra-indications of this vitamin complex are individual hypersensitivity to vitamins and its other components. A special addition to prescribing the drug to children under 10 years of age: the use should be careful and only after a careful analysis of the risk of taking high doses of vitamins of this group by patients of this age category.
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Side effects B-complex, multi-tabs
As a rule, this vitamin complex is well tolerated - provided that the recommended dose and regimen are met. When taking B-complex tablets, multi tabs before meals, there may be a feeling of discomfort in the abdomen. In such cases it is recommended to use the drug after eating.
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Attention!
To simplify the perception of information, this instruction for use of the drug "B-complex, multi-tabs" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.