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Avandia
Last reviewed: 03.07.2025

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Diabetes mellitus is a serious problem of the modern world. Its treatment strongly depends on the characteristics of the organism and tolerance to certain substances and ingredients of medicines. And yet there is a drug that has proven itself in the treatment of diabetes mellitus - Avandia.
Indications Avandia
Avandia is used to treat type 2 diabetes. It is prescribed as monotherapy if a person lacks physical activity and diet therapy. In some cases, it is used with metformin and insulin to improve glycemic control.
Release form
Avandia is a medical product containing rosiglitazone. The tablets are pentagonal in shape and coated with an orange shell. Available in blisters of 7 and 14 pieces, containing rosiglitazone at 4 and 8 mg/tab.
Pharmacodynamics
Avandia is an oral drug and belongs to the group of thiazolidinediones. The main component of the drug, rosiglitazone, reduces blood glucose levels and improves the body's response to insulin. The drug also improves metabolic processes in the body and reduces the level of fatty acids in the blood. Rosiglitazone also has a positive effect on the functions of β-cells, which helps increase the mass of the islets of Langerhans in the pancreas and increases insulin levels. The drug has a positive effect on pancreatic secretion, preventing excessive insulin production. All this normalizes the body and promotes recovery from diabetes.
Pharmacokinetics
After a rosiglitazone tablet enters the body, within an hour the beneficial substances begin their work to improve the condition of the blood. Taking the drug after meals significantly increases the time it takes for rosiglitazone to break down in the body. Accordingly, I recommend taking Avandia on an empty stomach. In the human body, rosiglitazone undergoes intensive metabolism by N-demethylation. The substances of the drug are excreted from the body in the form of metabolites through the bladder or in the form of feces 3-4 hours after administration. Accordingly, the drug should be prescribed to people suffering from impaired renal function only after a thorough examination and passing the appropriate tests.
Dosing and administration
Dosage indications are prescribed strictly individually. As a rule, the daily dose of the drug is used in 1-2 approaches. For adults, the daily dose of the drug is 4 mg. If there is no result, then to increase the effectiveness of treatment after 6-8 weeks, the daily dose should be increased to 8 mg/day on the recommendation of a doctor. For patients over 45 years of age, changes in dosage are not applied.
Use Avandia during pregnancy
You should not take Avandia during pregnancy.
Contraindications
The drug Avandia is contraindicated for use by children under 18 years of age, people with impaired renal and hepatic function, and women in position during lactation. It is also not recommended to use Avandia in type 1 diabetes. However, when using the drug Avandia on the recommendation of the attending physician, side effects are possible.
This drug is strictly contraindicated for children.
Overdose
Thus, when using the drug, edema or hypercholesterolemia may occur. This will indicate the occurrence of side effects in the metabolic system. There is also an increase in the activity of liver enzymes, peripheral edema, and in rare cases, anemia.
Interactions with other drugs
Storage conditions
The medicinal product Avandia should be stored out of the reach of children at a temperature not exceeding 25 ◦.
Shelf life
The shelf life of the drug is 2 years.
Attention!
To simplify the perception of information, this instruction for use of the drug "Avandia" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.