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Health

List Analyzes – C

1 5 A B C D E F G H I L M N O P R S T U V W Y
Diagnosis of chlamydia with PCR is the most sensitive and specific method of all used in laboratories at the present time. The sensitivity of the method is 95-97%, and the specificity is 95-98%.

IgM antibodies are detected in the acute period of infection (already 5 days after its onset). The peak of antibodies IgM falls on 1-2 weeks, then there is a gradual decrease in their titer (as a rule, they disappear after 2-3 months even without treatment). Antibodies of the IgM class are directed against the lipopolysaccharide and the main protein of the outer membrane of chlamydia.

The method is based on the detection of Chlamydia trachomatis antigens in scrapings from the urethra, cervical canal and conjunctiva by ELISA with a visual evaluation of the result (sensitivity is more than 79%, specificity is more than 95%). This method is based on the presence in chlamydia of the rhodospecific lipopolysaccharide antigen.
Ceruloplasmin is a protein with a molecular weight of 150,000 daltons, contains 8 ions of Cu1 + and 8 ions of Cu2 +. The main copper-containing plasma protein belongs to alpha2-globulins; it accounts for 3% of the total amount of copper in the body and more than 95% of serum copper.
CA 19-9 is a glycoprotein found in the fetal epithelium of the pancreas, stomach, liver, small and large intestine, lungs. In adults, this antigen is a marker of the glandular epithelium of most internal organs and a product of their secretion. It should be noted that the antigenic determinant of the CA 19-9 antigen and the Ar of the Lewis blood group (Le (ab-)) are encoded by a single gene.
SA-72-4 is a mucin-like glycoprotein with a molecular mass of 400,000. It is expressed in many fetal tissues and is practically not found in adult tissues. The level of CA-72-4 is increased in the blood serum of patients suffering from such malignant tumors of glandular genesis as carcinoma of the stomach, colon, ovaries, lungs.

Diagnosis of superficial candidiasis is based on the detection of fungal elements in a stained smear. With visceral forms of candidamycosis, serological studies are of great diagnostic importance.

Cancer-embryonic antigen - glycoprotein, formed during embryonic development in the gastrointestinal tract. The maintenance of cancer-embryonic antigen affects smoking and, to a lesser extent, alcohol intake.

CA-15-3 is an antigen of the membrane of cells of metastatic breast carcinoma. In healthy individuals, it can be determined on the epithelium of secreting cells and in secrets. CA-15-3 has a sufficiently high specificity for carcinoma of the breast in comparison with its benign diseases.
CA-125 is a glycoprotein present in serous membranes and tissues. In women of childbearing age, the main source of CA-125 is the endometrium, which is associated with a cyclic change in the level of CA-125 in the blood, depending on the phase of the menstrual cycle.
Vitamin D3 (cholecalciferol) is formed in the skin of 7-dehydrocholesterol under the influence of sunlight or enters the body with food. The synthesized and received vitamin D3 is transported by blood to the liver, where in mitochondria it is converted to 25-hydroxyvitamin [25 (OH) D3].
Collagen type I accounts for more than 90% of the organic matrix of bone. As a result of permanent remodeling of bone tissue collagen type I is destroyed, while its fragments enter the blood.
C-reactive protein (CRP) is a protein consisting of 5 identical, non-covalently linked ring subunits. C-reactive protein is detected in the blood serum for various inflammatory and necrotic processes and is an indicator of the acute phase of their course.
C-peptide - a fragment of the molecule of proinsulin, as a result of the cleavage of which forms insulin. Insulin and C-peptide are secreted into the blood in equimolar amounts. The half-life of the C-peptide in the blood is higher than that of insulin, so the C-peptide / insulin ratio is 5: 1.

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