Adrianol

Adrianol is a vasoconstrictive drug used in ENT practice as a local remedy.

[1], [2], [3], [4]

Indications Adrianol

Indications for its use are:

• acute form of cold;
• sinusitis;
• chronic form of the common cold (for short treatment);
• preparation for the procedures of diagnosis in the otolaryngologist;
• preparation for otolaryngology operations.

[5], [6], [7], [8]

Release form

Produced in the form of nasal drops. One package contains a special bottle-dropper with a volume of 10 ml.

[9], [10], [11]

Pharmacodynamics

The medicine contains trimazolin with phenylephrine, which have vasoconstrictive properties - it is due to the ability to narrow the blood vessels the medicine reduces the swelling of the nasal mucosa. This allows you to normalize breathing through the nose and reduce pressure in the middle ear and sinus. The dosage form has a viscous consistency, as a result of which a prolonged effect appears on the nasal mucosa.

[12], [13]

Dosing and administration

Children's drops for children from 3 years must be digested three times a day, 2 drops in each of the nostrils.

Children from 7 years of age and adults are dripped 4 times a day, 1-3 drops into each of the nostrils.

The duration of use of the drug should be a maximum of 7 days, after which it is required to take a break in several days.

[17], [18], [19], [20]

Use Adrianol during pregnancy

Testing on the safety of use of Adranol during pregnancy was not conducted, so it is not recommended to use the medication in this period.

Contraindications

Among the contraindications:

• pheochromocytoma;
• individual intolerance to phenylephrine, trimazoline, and also auxiliary substances;
• glaucoma;
• IHD;
• elevated blood pressure;
• thyrotoxicosis;
• severe form of kidney pathology;
• atrophic form of rhinitis;
• atherosclerosis.

[14]

Side effects Adrianol

Due to the use of drops, such adverse reactions can occur:

• local: pain, burning or dryness in the nasal mucosa, as well as her edema. In addition, there are abundant discharge from the nose and a disorder of taste sensitivity;
• systemic: the appearance of headaches and dizziness, and in addition nausea, increased blood pressure, the development of tachycardia and allergies;
• prolonged use can lead to nasal congestion, a runny nose, as well as atrophy of the nasal mucosa.

[15], [16]

Overdose

Among the manifestations of drug overdose: rapid fatigue, the appearance of nausea or dizziness, increased blood pressure, insomnia or fever, the development of tachycardia or reflex bradycardia.

Interactions with other drugs

When combined with MAO inhibitors or antidepressants, the risk of increasing blood pressure may increase.

[21]

Storage conditions

It is required to keep the medicine in standard conditions for medicinal products - a place that is closed from the sun and moisture penetration, and also inaccessible to children. Temperature indices - no more than 25 ° С.

[22], [23]

Shelf life

Adrianol is allowed to be used for 3 years from the date of manufacture of the medicine.