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Last reviewed: 23.04.2024
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Actival is a multivitamin drug.
Indications Activala
The drug is used to prevent hypovitaminosis, which can be triggered by various factors:
- unbalanced diet (for example, diet or vegetarianism);
- severe loss of fluid (eg, associated with chronic diarrhea );
- disorders of absorption processes;
- taking certain medications (contraception, individual antibiotics or chemotherapeutic drugs);
- increased need for vitamins in connection with significant mental or physical stress, trauma, illness, and beyond this in the post-operation period, with influenza, ARI and infections that are recurrent.
[1],
Release form
Release of the substance is made in tablets, in the amount of 30 or 60 pieces inside the bottle. In a pack - 1 such a bottle.
[2]
Pharmacodynamics
Medicinal properties develop due to the activity of vitamins, which are constituent elements of the drug. They participate in a variety of metabolic processes regulating the homeostasis of the body both in the normal state and in the disease. The combination of vitamins helps to develop a more versatile and pronounced biological effect.
Retinol is extremely important for the work of the visual organs, and besides it is required for the processes of growth and differentiation of cells, and promotes a full-fledged immune activity.
Thiamine is a coenzyme involved in energy metabolism. It regulates the operation of the PNS, as well as muscle tone and appetite.
Riboflavin is included in the system of flavoprotein enzymes, activates the activity of pyridoxine, and besides it is in the composition of retinal pigments and participates in adrenocortical metabolic processes.
Niacin is coenzyme in the processes of cellular respiration (NAD, as well as NADP); it affects growth processes, and besides it has hypocholesterolemic influence.
Pantothenate calcium is a prosthetic category of CoA elements, as well as ACP.
Pyridoxine - how coenzyme is involved in the activity of enzyme systems of protein-carbohydrate metabolism, and with it in the processes of protein metabolism.
Cyanocobalamin is extremely important in the processes of DNA exchange, as well as in the replication and differentiation of cells (neural tissues, spinal and epidermal cells), and besides it is the main participant in the normal process of homocysteine metabolism.
Ascorbic acid is the main extracellular antioxidant and an indispensable element within connective tissues. The substance is involved in the metabolic processes of tyrosine with folic acid and tryptophan, and in addition in the formation of dentin with heme and iron absorption.
Cholecalciferol is the main hormone necessary for metabolic processes inside bone tissues. It has an immunomodulatory effect, and also shows endocrine activity.
Vitamin E is the main antioxidant of the extracellular type, it is very important for the processes of cellular respiration, and besides for the complete metabolism of DNA with red blood cells.
Folic acid is very important in the metabolic processes of RNA with DNA, and in addition, when forming heme, maintaining optimal values of homocysteine and the transformation of niacin.
Biotin is involved in decarboxylation processes with carboxylation, as well as deamination of protein and carbohydrate metabolism.
Rutin is an antioxidant; strengthens vascular strength.
Phytomenadione helps maintain the integrity of the osseous system and induces γ-carboxylation processes, which is why it becomes important components of osteocalcin formation and factors of blood uptake.
PABC is involved in folic acid metabolism.
Boron mediated takes part in metabolic processes of bone tissues, and at the same time in the work of individual enzymes (for example, chymotrypsin or alcohols dehydrogenase).
Calcium is the main structural component of teeth with bones, and also transforms signals inside cells of a variety of tissues (among them the endocrine system, the central nervous system and muscle tissue).
Phosphorus is also an integral part of the structure of teeth with bones, and is also very important in the metabolism of carbohydrates with fats and proteins.
Chromium is an important participant in carbohydrate metabolism (insulin), and at the same time it stabilizes the activity of RNA.
Copper is the main component of antioxidant protection; participates in the processes of metabolism of connective tissues, and also regulates the binding of nitric oxide.
Iodine is a structural component of the thyroid hormones.
Iron is part of the structure of hemoglobin, and also takes part in the activity of individual enzymes (for example, protective actio-oxidant functions).
Magnesium is an important component of the structure of bone tissues and transforms signals within cells (for example, inside HC and CCC).
Manganese is necessary for antioxidant protection, as well as for the regulation of metabolic processes involving fats with amino acids and for the citrate cycle.
Molybdenum takes part in the exchange processes of RNA with DNA and is a catalyst for the decomposition of S-amino acids.
Selenium is an important component of the antioxidant defense, as well as the metabolic processes of the thyroid hormones.
Vanadium participates in carbohydrate metabolic processes.
Zinc plays an important role as a coenzyme of enzyme systems in the exchange processes of DNA with RNA, as well as proteins with carbohydrates. The substance has an immunomodulating effect and acts as an antioxidant.
Glycine and myoinositol with succinic acid are vitamin-like components; they are based on chemical internal artificial processes (among them and hematopoietic). They act as intermediaries for the exchange processes that are important in protecting against the effects of free radicals.
Use Activala during pregnancy
The drug can be used in pregnancy or lactation - provided that the recommended dosages are observed.
Contraindications
The main contraindications:
- a disorder in kidney function associated with the use of coumarin anticoagulants;
- progression of thyrotoxicosis or the period of its therapy;
- hypervitaminosis of type A or D;
- hypercalcemia, hemosiderosis or hemochromatosis;
- hepatolenticular degeneration;
- the presence of intolerance with respect to the elements of the drug.
Overdose
Intoxication develops only in case of non-compliance with the recommended treatment regimen.
In case of an overdose, it is necessary to perform gastric lavage, take activated charcoal and perform symptomatic procedures.
Interactions with other drugs
It is required to use with caution the drug in combination with drugs, which include retinol, calciferol, vitamins E and K - to avoid intoxication.
Taking together with drugs containing fluoroquinolone, bisphosphonate, tetracycline, antacids, and besides phenytoin or penicilamine, it is necessary to observe a minimum of 2-hour interval between their use (because absorption of Activala can be violated).
Pyridoxine, even in small amounts, can weaken the effectiveness of levodopa, thyroxine-containing drugs and vitamin B9 antagonists (inorganic elements can combine with iodine).
Storage conditions
The actives should be kept in a closed place from children, dry place. The temperature is within the limits of 15-25 ° C.
Shelf life
The actives can be used within 36 months from the date of manufacture of the pharmaceutical.
Attention!
To simplify the perception of information, this instruction for use of the drug "Active" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.