Acriderm for psoriasis: ointment, cream

Psoriasis is a complex skin disease that requires constant attention of the patient, not forgiving ignoring the problem, negligent treatment. In the arsenal of the fight against the disease, many techniques have been accumulated, consisting both in the application of complex complex methods of treatment (medicamentous, homeopathic, folk, sanatorium-resort), and in the application of external means of local use. For today the most effective of them are hormonal external preparations. Acriderm with psoriasis is one such tool, based on the hormones of the adrenal cortex.

[1], [2], [3], [4], [5]

Indications of the acriderma in psoriasis

Indications for the use of acryderma in psoriasis are pronounced cutaneous manifestations of it in the form of redness, raised tubercles above the surface of the skin, peeling, resembling wax plaques or scales. Their appearance and spread to new healthy areas of the skin is accompanied by itching, burning, and other unpleasant sensations. Psoriasis is a chronic, incurable to date disease with stages of remission and relapse. For external effects on the lesions of the skin resort to ointments, gels, creams in order to soften the thickened skin, cause an anti-inflammatory effect, remove the itch. Hormonal external means of treatment of psoriasis give a quick result, although they have a number of contraindications. They usually start with less active and simple drugs, such as prednisolone, hydrocortisone. But in the more severe stages of psoriasis resort to potent hormonal drugs, which is an acryderm.

[6], [7]

Release form

The form of the release of acryderma is an ointment of white or light cream color, as well as a white cream. Aluminum tube, which contains the drug, contains either 15 or 30 grams of ointment or cream. The tubes are packed in a cardboard box. The main active substance of acryderm is betamethasone. There are other forms of release of the drug, with anti-inflammatory, antifungal elements. So, acantherm genta is a combination of betamethasone with an antibiotic, akriderm GK - with an antifungal agent, akriderm SK - with salicylic acid.

Acriderm SK for psoriasis

Acriderm SK for psoriasis is indicated for topical application, taking into account its softening effect on the horny layers of the skin. This makes it possible for betamethasone, which is part of the ointment, to penetrate deeper into it and more efficiently affect the lesions. This characteristic is provided by the influence of salicylic acid, its antiseptic and exfoliating properties (in a gram of ointment contains 30 mg of salicylic acid).

Acriderm GK for psoriasis

Acriderm HA in psoriasis is another combination of betamethasone with gentamycin (1 mg in 1 gram of ointment), which provides antibacterial action of the drug, and clotrimazole (10 mg), which has an antifungal effect due to the negative effect on the production of the main constituent of the cell membrane of fungi. Indications for the use of the drug are complications in psoriasis, provoked by various infections.

Ointment acryderm for psoriasis

Acryderm ointment for psoriasis - packed in a tube, a homogeneous dense consistency, light color, has a weak specific odor. The action of the drug is aimed at eliminating the foci of inflammation, itching, exudative phenomena.

Acryderma cream for psoriasis

This form of release of drugs, like creams, involves the use of oils or other fats. The acrydermal cream for psoriasis is a remedy, of a lighter texture than an ointment, which contains in addition to betamethasone, auxiliary substances such as Vaseline, wax, paraffin, etc. The direction of action is the same as that of ointments: it prevents the reproduction of affected skin tissues, has an anti-inflammatory effect , antipruritic, anti-edema.

Pharmacodynamics

The main effect of the drug is aimed at arresting the symptoms of psoriasis, improving the quality of life of patients. The pharmacodynamics of the acryderm consists in its action on the leukocytes in order to reduce their accumulation, in inhibiting the release of enzymes capable of damaging the cell membrane. Application of the drug prevents the development of a "trigger mechanism" of inflammation, reduces the permeability of blood vessels and tissues, proliferation of lesions, the formation of edematous phenomena. The hormonal component of the acryderm provides a strong and rapid effect of application, cleansing the skin and removing itching, burning, pain.

Pharmacokinetics

The pharmacokinetics of the acryderm indicate a minor ingestion of the drug into the blood because of the cutaneous route of its introduction into the body. The application of occlusive dressings that prevent the penetration of air, significantly increases the ability of the drug to enter into and develop side effects, but in the case of acryderma with psoriasis, dressings are not recommended.

Dosing and administration

Acriderm for psoriasis is for external use. Ointment or cream is applied with a thin layer of rubbing light movements on the damaged areas twice a day, making sure that the drug does not get on the mucous surfaces, especially the eyes. If the pockets of rashes are large, then it is necessary to start from a small surface, gradually increasing the area. Duration of treatment can last from two to four weeks. Therapy of facial surfaces with acryderma should not be long (up to a week), because The skin of the face is more sensitive and tender, and its thinning, atrophy may occur. How often can an aceridram be used in psoriasis? During the year, you can repeatedly resort to treatment with this remedy, but with the permission of the doctor, to avoid addiction.

Use of the acriderma in psoriasis during pregnancy

Since acrydem is a corticosteroid (hormonal) agent, the use of acryderma in psoriasis during pregnancy is not recommended. When there is an acute need for the drug, the doctor must assess the degree of risk of such a step and the predominance of benefits over the negative effects on the body of a woman and a fetus. When recognizing the advisability of receiving therapy, the time interval of the drug should be small, and the dose should be moderate.

Contraindications

Contraindications to use, in the first place, is the age of a person (children under one year is not prescribed) and an allergy to betamethasone or to other components of the drug. Also, the drug can not be used for patients suffering from dermatological diseases of fungal, viral or bacterial nature (syphilis, chicken pox, herpes, skin tuberculosis, etc.). For malignant skin diseases, open wounds, trophic ulcers, vulgar acne, birthmarks, the use of acrym is also not recommended. Careful approach to prescribing the drug should be for people with diabetes, tuberculosis, eye diseases: glaucoma, cataracts. When using the face, there is a risk of atrophic changes, so treatment should not exceed 5 days.

[8], [9]

Side effects of the acriderma in psoriasis

Side effects of acryderma in psoriasis can be manifested in the form of rashes on the skin, itching, irritation, excessive facial hair loss in women, the appearance of pigmentation spots, etc. If the use of the drug was long-lasting and besides bandages that did not pass air, atrophy and maceration (swelling) of the skin, the appearance of chunks, the expansion of small vessels of the skin, hair growth in women of the male type (beards and mustaches). With prolonged exposure to betamethasone on the skin surface, gastritis, ulcers on the mucous membranes of the gastrointestinal tract, detection of sugar in the urine, changes in the work of the adrenal glands, and an increase in blood pressure may occur. In case of any deviations from the usual condition, stop the acryderma treatment and consult a doctor to clarify what is happening. He will assess the situation and, possibly, prescribe an alternative treatment.

[10],

Overdose

The likelihood of an acute overdose with betamethasone is very small, but chronic is quite possible. It should not be forgotten that this is a hormonal drug containing hormones of the adrenal cortex. Prolonged use of it can cause an excess of these hormones in the body (hypercorticoid syndrome), and this is fraught with the development of diabetes mellitus, muscle atrophy and structures of all organs. In such cases, stop the therapy with ointment or cream gradually, without severing the treatment dramatically. Interactions with other drugs are not defined.

Storage conditions

Both ointment and acryderm cream should be stored in places inaccessible to children, at a temperature of 15 to 25 ° C, do not freeze.

Shelf life

The shelf life of the cream is 4 years, the ointment is 2 years.

Reviews

Most patients note a positive therapeutic effect of the drug, which leads to the onset of a prolonged remission. Many after 2-3 weeks of use felt a decrease in flashes of rashes, a reduction in itching, swelling, flaking, burning of the skin. To the positive aspects of the acriderma include the ease of use, different forms of release of the product, the absence of a sharp odor, affordable price. Some patients in their reviews indicate a rapid accustoming to acryderma and a gradual decrease in the effectiveness of treatment. There are also patients who have experienced adverse reactions. Unfortunately, the acryderm does not become a panacea for psoriasis, which patients so expect, but it is possible to alleviate the severity of the patients' conditions.