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Abitur
Last reviewed: 23.04.2024
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Abitur is a drug that helps lower cholesterol levels. And, as you know, cholesterol is deposited on the vascular system of the brain and heart, which complicates life. The abitator lowers the level of cholesterol in the blood, which means it avoids heart attacks, strokes and hypertension, the causes of which are elevated cholesterol levels. Let's take a closer look at the peculiarities of the abortor, the way it is used and the existing contraindications.
Indications Abitur
Indications for the use of the abortion suggest the use of the drug to reduce elevated levels of cholesterol and apolipoprotein.
Indications for the application of the customer:
- Hyperlipidemia
- Hypercholesterolemia
- Heterozygous hyperlipidemia
Abiters are prescribed to patients who have a high risk of developing a stroke or myocardial infarction, which can lead to circulatory disorders in the brain. It is very important, before the reception of the abortor to monitor the indicators of kidney and liver function, to regularly conduct urinalysis and feces.
Abitur, like other drugs, inhibitors can cause myopathy, which manifests itself as muscle pain, weakness, fever. In rare cases, during the admission of patients, an increase in the level of creatine phosphokinase is observed in patients. The entire period of application of the abortion should be under the control of the attending physician. In case of symptoms of myopathy, the drug should be stopped. During admission, patients are prescribed a strict hypocholesterolemic diet, which improves the uptake of the drug by the body and increases its preventive functions.
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Release form
Form of release of the tablets:
- round biconvex tablets coated with a gray color with embossed in the form of a heart on one side and smooth on the other (10 mg);
- round biconvex tablets coated with a light orange color, smooth on both sides (20 mg).
1 tablet of the abater is coated with a coating that contains atorvastatin calcium, equivalent to 10 and 20 mg. As auxiliary substances, calcium carbonate, microcrystalline cellulose, lactose, iron oxide (black, red, yellow) and other substances are used.
Pharmacodynamics
Pharmacodynamics of the abortion is the interaction of many drugs. Thus, the pharmacodynamics of the abortor is represented by atorvastatin calcium, which is a synthetic, hypolipidemic agent. In other words, it is an enzyme that can suppress the synthesis of cholesterol in the liver. Suppression of cholesterol in the liver helps lower intracellular amounts of cholesterol. And this, in turn, leads to an increase in cholesterol uptake from the blood and restoration of intracellular cholesterol homeostasis.
Atorvastatin is working to lower the cholesterol level in the blood, especially in patients with heterozygous and homigous familial hypercholesterolemia, mixed dyslipidemia and non-familial forms of hypercholesterolemia. Pharmacodynamics abitera responsible for lowering cholesterol in the blood due to atorvastininu, lower triglycerides and increasing the level of apolipoprotein A.
Pharmacokinetics
The pharmacogenetics of the abortion is based on the effective work of all the components that make up the drug. The main active substance of the abortion is atorvastatin, which has an increased absorption in the blood and is maximally concentrated in the plasma 1-2 hours after ingestion.
The use of food, simultaneously with the use of the drug, significantly reduces the absorption of the latter from 9 to 25%. If the drug is taken at night, then its pharmacokinetics is lower, in comparison with taking the drug in the morning and on an empty stomach. Atorvastatin binds 98% to plasma proteins. The highest therapeutic effect during the application of the abortor is seen after 14 days of continuous administration of the drug.
Dosing and administration
The method of application and doses of the abortion completely depend on the age and complexity of the disease of the person to whom the drug is prescribed. Note that before starting treatment it is necessary to observe a hypocholesterolemic diet.
The method of application and the dose of the adult for adults is 10 mg once a day, and the therapeutic dose is 10 to 80 mg per day. The drug should be taken once a day at any time, preferably before and after meals. Please note that the dose of the drug should be determined by the attending physician, depending on the level of cholesterol in the blood. Also, during the use of the drug, it is necessary to monitor the level of lipoproteins in the blood. This allows you to monitor the dose of the drug. The maximum daily dose of the drug is 80 mg.
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Use Abitur during pregnancy
The use of the abortion during pregnancy is not thoroughly studied. Therefore, accurately predict the result of treatment and the effect of the drug on the course of pregnancy and fetus is not possible.
The abortion during pregnancy is prescribed only in those cases when the risk to the fetus is not considered, since the benefit of treatment for the mother is important. As for the reception of the abortion by nursing mothers, the drug enters breast milk, although not in large quantities. Therefore, when taking the abortion in the postpartum period, you should stop breastfeeding. Safety and effectiveness of the drug in children have not been studied.
Contraindications
Contraindications to the use of the abortion are based on hypersensitivity to any ingredient that is part of the drug. These are liver diseases, an elevated level of transaminase activity in the blood and unknown etiology. Also, the drug is prohibited for use during pregnancy and lactation.
Contraindications to the use of the abortion with caution are prescribed to patients who abuse alcohol and have liver disease. The drug is administered with caution to women of reproductive age and to those who use drugs for contraception.
Side effects Abitur
Side effects of the abortors are:
- Constipation
- Dyspepsia
- Nausea
- Flatulence
- Abdominal pain
- Myalgia
- Diarrhea
- Asthenia
- Headache
- Allergic reactions
- Insomnia
In some cases, in addition to the above-described side effects, it is possible:
- Dizziness
- Pancreatitis
- Vomiting
- Myopathy
- Hepatitis
- Paresthesia
- Skin rashes
- Hypoglycaemia
- Itching
- Hyperglycaemia
- Jaundice
Side effects of the abortion should be controlled by the attending physician, and in particularly severe cases, the drug is discontinued.
Overdose
Overdose of the abortion can occur in case of non-compliance with the prescribed dosage of the drug and the time of admission.
Symptoms of an overdose by an abortion:
- Myopathy
- Neuromuscular excitability
- Vomiting
- Impaired liver function
- Myoclonia
- Disorders of consciousness
- Nausea
- Diarrhea
In order for the overdose symptoms of the abortor to go away, you need to contact your doctor and stop using the drug.
Interactions with other drugs
Interaction of the abiator with other drugs is possible, but only under the supervision of the attending physician. It is forbidden to take the abortion with suspensions of oral antacids, which contain hydroxides of magnesium and aluminum.
It is necessary to monitor the condition of patients who use the abitator. Especially the application of the customer with:
- Erythromycin
- Larntromycin
- Azithromycin
- Atorvastatin
- Terfenadine
Also, you should take care of the use of the abortion with oral contraceptives, which contain norethindrone and ethinyl estradiol. And also the interaction of the abitor and protease inhibitors, which increase the concentration of atorvastatin in plasma.
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Storage conditions
Store the product in its original packaging, in an unacceptable place for children, at a temperature of no higher than 25 ° C.
If the storage conditions of the customer are not respected, the drug may deteriorate, change its color and properties. It is very important not to take the drug with other drugs, as this will lead to adverse reactions of an irreversible nature.
Shelf life
The expiration date of the customer is 2 years from the date of production, which is indicated on the package with tablets. Pay attention to what is a pill, any color changes in the drug indicate a failure to comply with the rules of storage or expiration of the drug. Abiters are only released on the prescription of the attending physician.
Attention!
To simplify the perception of information, this instruction for use of the drug "Abitur" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.