Quadevit

Quadevit is a combined vitamin preparation that contains several B vitamins (B1, B6 and B12) in combination with nicotinamide (vitamin PP). This preparation is often used for complex treatment and prevention of deficiency of these vitamins.

The form of release, method of administration and dosage of "Quadevit" may vary depending on the country and manufacturer, but usually it is a tablet or injectable solution. Here are the general recommendations:

1. Form of release:

   • Tablets: Quadevita tablets are intended for oral administration. They may be coated or have a special coating to improve absorption.
   • Injectablesolution: Injectable "Quadevit" is administered intramuscularly or intravenously by medical personnel.

2. Method of Application:

   • Tablets: Tablets are usually taken orally with or after meals. They are washed down with a glass of water.
   • Injectablesolution: Injectable "Quadevit" is administered intramuscularly or intravenously, observing all rules of asepsis and antisepsis.

3. Dosage:

   • The dosage of "Quadevit" may vary depending on age, health and medical conditions.
   • It is usually recommended to take one tablet one or more times a day. For injections, the dosage can be prescribed by your doctor according to your specific situation.

4. Duration of admission:

   • The duration of taking "Quadevit" is determined by a doctor and can vary from several weeks to several months, depending on the goals of treatment or prevention.

5. Individualized recommendations from a physician:

   • The doctor can recommend individual adjustments to the dosage and regimen of "Kvadevit" depending on the nature of the disease and the patient's condition.

It is important to remember that these are general recommendations, and the specific dosage and regimen of Quadevit should be determined by a physician. Patients should follow the doctor's instructions and communicate regularly with the doctor regarding any questions or concerns that arise during treatment.

Indications Quadevita

1. Vitamin and mineral deficiencies: "Quadevit" can be used to compensate for deficiencies of vitamins (such as vitamins B, C and D) and minerals (e.g. Iron, zinc, magnesium), especially in cases of malnutrition or increased need of the body in them.
2. Improvement of general condition: The drug can be used to increase the general tone of the body, improve the immune system and the body's resistance to stress and physical exertion.
3. Enhancing endurance: Quadevit may be useful for athletes and people with active lifestyles to improve endurance and recover quickly from exercise.
4. Improved study and work performance: The B vitamins in the product may help improve nervous system function and concentration, which may be beneficial for students, schoolchildren, and people with active lifestyles.
5. Maintaining health in times of stress and overwork: "Quadevit" can be used in periods of increased workload, stress, overwork, after illness, surgery, etc. For rapid recovery of the body.

Release form

1. Tablets: Quadevita tablets are intended to be taken orally. They can have different dosages and often contain a combination of B vitamins (B1, B6, B12) combined with nicotinamide (vitamin PP). Tablets are usually sold in packs with instructions for use.
2. Solution for injection: Quadevit may also be available as a solution for injection. This solution is intended to be given intramuscularly or sometimes intravenously. The solution for injection is usually supplied in ampoules or vials, each containing a certain amount of active ingredient.

Pharmacodynamics

1. Tocopherol (vitamin E):

   • Antioxidant Action: Tocopherol is a powerful antioxidant that protects cells from oxidative stress and helps prevent damage to cell membranes.

2. Ascorbic acid (vitamin C):

   • Antioxidant Action: Vitamin C is a strong antioxidant that protects cells from free radical damage.
   • Involved in collagen synthesis: C is essential for the synthesis of collagen, an important protein for healthy skin, joints and blood vessels.

3. Glutamic acid:

   • Involvementin amino acidmetabolism: Glutamic acid is involved in a variety of metabolic processes, including protein synthesis and amino acid metabolism.

4. Potassium:

   • Electrolyte balance: Potassium plays an important role in electrolyte balance, muscle and nerve function.

5. Calcium pantothenate:

   • Involved in the metabolism of carbohydrates and fats: Calcium pantothenate is an important component of coenzyme A, which is involved in the metabolism of carbohydrates and fats.

6. Copper:

   • Involved in iron metabolism: Copper is essential for normal iron metabolism in the body.

7. Methionine:

   • Sulfur Source: Methionine is an important source of sulfur and is involved in protein synthesis.

8. Nicotinamide (vitamin B3):

   • Participation in metabolism: Nicotinamide is involved in a multitude of biochemical processes, including metabolism and energy metabolism.

9. Pyridoxine (vitamin B6):

   • Amino acid metabolism: B6 plays an important role in amino acid metabolism and the synthesis of some neurotransmitters.

10. Retinol (vitamin A):

    • Vision: Retinol is essential for maintaining eye health and vision.

11. Riboflavin (vitamin B2):

    • Involvement in metabolism: Riboflavin is involved in a number of important metabolic processes, including metabolism.

12. Rutoside (vitamin P):

    • Strengthening of blood vessels: Rutoside helps to strengthen the vascular wall and increase their elasticity.

13. Thiamine (vitamin B1):

    • Energy metabolism: Thiamine is involved in metabolizing carbohydrates and converting them into energy.

14. Folic acid (vitamin B9):

    • Involved in DNA synthesis: Folic acid is essential for DNA synthesis and cell growth.

15. Cyanocobalamin (vitamin B12):

    • Blood formation: B12 plays an important role in the formation of red blood cells and the normal functioning of the nervous system.

16. Fitin:

    • Antioxidant Properties: Phytin has antioxidant properties and may help protect cells from free radical damage.

Pharmacokinetics

1. Absorption: The vitamins and minerals in Quadevit are generally absorbed from the gastrointestinal tract after oral administration. The rate and completeness of absorption may vary depending on the chemical form of each component.
2. Distribution: Vitamins and minerals are distributed throughout the body via the bloodstream and may accumulate in tissues and organs depending on their solubility and specific transport mechanisms.
3. Metabolism: Some vitamins may undergo metabolic processes in the liver or other tissues, resulting in the formation of active or inactive metabolites.
4. Excretion: Excess water-soluble vitamins (e.g., vitamin C and B-group vitamins) are excreted through the kidneys as urine, while fat-soluble vitamins (e.g., vitamins A, D, E, and K) may accumulate in the body and be excreted through the bile.
5. Half-life: Half-life times can vary considerably for different vitamins and minerals, depending on their chemical nature and the way they are metabolized.

Dosing and administration

1. Dosage:

   • The dosage of Quadevit may vary depending on age, health and medical conditions.
   • It is generally recommended to take one tablet one or more times a day, depending on your body's needs and your doctor's recommendations.
   • For the injectable version, the dosage can be prescribed by a doctor according to the specific situation.

2. Method of Application:

   • If they are tablets, they are usually taken orally (orally) with or after a meal, with a glass of water.
   • For injection, if this form is available, the injectable solution is administered intramuscularly or intravenously by medical personnel.

3. Duration of admission:

   • The duration of taking Quadevit may vary depending on the nature of the vitamin deficiency and response to treatment.
   • The course of administration is usually a few weeks, but can be extended on the advice of a doctor.

4. Individualized recommendations from a physician:

   • The doctor may recommend individual adjustments to the dosage and regimen of Kvadevit depending on the nature of the disease and the patient's condition.

Use Quadevita during pregnancy

The use of any medications, including vitamin complexes, during pregnancy requires special attention and consultation with a doctor.

During pregnancy, it is important to ensure not only your own health, but also the health of your developing fetus. Some vitamins and minerals contained in preparations such as Kvadevit may be beneficial for pregnant women, but it is important to remember the following:

1. Dosage: Some vitamins and minerals may be harmful in high doses during pregnancy. Before starting to use Quadevit or any other vitamin complex during pregnancy, you should consult your doctor to determine the appropriate dosage.
2. Ingredients: Pay attention to the composition of the product and make sure it does not contain ingredients that may be harmful to pregnancy. For example, some vitamins can be harmful in high doses and some herbal supplements can cause problems.
3. Individual needs: Vitamin and mineral requirements may vary among pregnant women depending on their general health, nutrition and other factors. Therefore, recommendations for vitamin supplementation should be individualized and based on specific needs.

Contraindications

1. Hypersensitivity: Patients with known hypersensitivity to any of the ingredients of the drug (including vitamins or additional substances) should avoid its use due to the risk of allergic reactions.
2. Hypervitaminosis: In case of excessive consumption of vitamins, hypervitaminosis may occur, which may lead to various side effects and complications. Therefore, "Quadevit" should be used only in accordance with the recommendations and dosage indicated in the instructions or as recommended by a doctor.
3. Hepatic insufficiency: In patients with severe liver dysfunction "Quadevit" should be taken with caution, as some vitamins may be metabolized in the liver and accumulate in case of liver dysfunction.
4. Kidney disease: Some vitamins, especially vitamin B6 (pyridoxine), may accumulate in renal dysfunction. Therefore, dosage adjustment of "Quadevit" is recommended for patients with severe renal dysfunction.
5. Pregnancy and breastfeeding: Before taking "Quadevit" during pregnancy or breastfeeding, a doctor should be consulted to make sure that it is safe to use in this case.
6. Children: Children should take "Kvadevit" only on the recommendation of a doctor to avoid exceeding the dosage and possible risk of hypervitaminosis.

Side effects Quadevita

1. Gastrointestinal disorders: Symptoms such as nausea, vomiting, diarrhea or constipation may occur.
2. Allergic reactions: Some people may experience allergic reactions such as skin rash, itching, or hives.
3. Hypervitaminosis: Prolonged and/or excessive use of "Quadevit" may result in hypervitaminosis, especially with respect to fat-soluble vitamins such as vitamins A and D, which may lead to toxic effects.
4. Metallic taste: Some people may experience a metallic taste in the mouth after taking Quadevit.
5. Changes in urine: Some people may notice changes in the color of their urine after taking Quadavit. This is usually due to the excretion of excess vitamins, especially vitamin B2 (riboflavin), which gives the urine a bright yellow color.
6. Other rare side effects: In rare cases, headaches, weakness, changes in blood pressure or blood glucose levels may occur.

Overdose

Overdose of water-soluble vitamins, such as vitamin C and B-group vitamins, often does not cause serious problems because excess of these vitamins are excreted in the urine. However, an overdose of fat-soluble vitamins such as vitamins A, D, E, and K can lead to toxic effects because these vitamins can accumulate in the body.

Symptoms of a Quadevit overdose may include:

1. Diarrhea.
2. Nausea and vomiting.
3. Abdominal pain.
4. Headache and dizziness.
5. High blood pressure.
6. Heart disorders.
7. Kidney problems.
8. Nervous disorders such as irritability and anxiety.

Interactions with other drugs

1. Preparations containing the same vitamins and minerals: When taking other multivitamin preparations or individual vitamins and minerals at the same time, there may be an overuse of certain components, which can lead to hypervitaminosis or hypermineralization.
2. Drugs affecting absorption: Some medicines may decrease or increase the absorption of vitamins and minerals from Quadevit. For example, drugs to reduce gastric acidity (e.g. Proton pump inhibitors) may decrease the absorption of iron and vitamin B12.
3. Drugs thataffect metabolism: Some medicines can affect the metabolism of vitamins and minerals in the body. For example, antibiotics can alter the metabolism of vitamin K, and drugs that affect the liver can alter the metabolism of fat-soluble vitamins (A, D, E, K).
4. Drugsthat increase the risk of side effects: Some drugs may increase the risk of side effects associated with certain vitamins or minerals. For example, drugs that increase the risk of bleeding (such as anticoagulants) may increase the risk of vitamin K hypervitaminosis.
5. Drugs thataffect urination: Drugs that affect urination (e.g., diuretics) may alter the excretion of water-soluble vitamins and minerals through the kidneys.
6. Drugs affecting digestion: Drugs that improve digestion (e.g. Enzymes) may increase the absorption of vitamins and minerals from Quadevit.

To minimize the risk of interactions with other drugs, it is recommended:

• Tell your doctor about any medications you are taking, including multivitamin medicines such as Quadevit.
• Follow the recommendations on dosage and regimen indicated on the drug package.
• Contact your doctor or pharmacist if you have any unexpected reactions or side effects.

Storage conditions

Storage conditions of Kvadevit may vary depending on the manufacturer and form of release of the drug. Usually storage recommendations are indicated on the package, they must be strictly observed to preserve the quality and effectiveness of the drug.

In general, vitamin complexes, including Quadevit, are usually stored under the following conditions:

1. Temperature: It is most often recommended to store at room temperature, which is usually between 15°C and 25°C. Avoid storage in locations with extreme temperatures.
2. Humidity: The drug should be stored in a place free from excessive humidity to prevent damage to tablets or capsules.
3. Light: Preferably store the preparation in a dark place or in a package that protects from direct sunlight to prevent decomposition of vitamins by light.
4. Availability to children: Ensure that the drug is stored out of reach of children to prevent accidental use.