Hydroperite

Hydroperite is a chemical compound that is a derivative of hydrogen peroxide. Its chemical formula is C6H12O4C6H12O4, which is a complex compound formed by hydrogen peroxide and urea. Hydroperite is used in medicine, cosmetology and other fields due to its antiseptic, disinfectant and bleaching properties.

In medicine, hydroperite is often used to treat wounds and cuts, as it helps to kill bacteria and prevent infections. In cosmetology, it is used as a hair and skin lightener and for removing age spots.

Hydroperite is available as tablets or powder, which are dissolved in water before use to produce a hydrogen peroxide solution of varying concentrations. This makes it convenient for storage and transportation, since in solid form it is less sensitive to light and temperature than liquid hydrogen peroxide.

Indications Hydroperite

1. Disinfecting wounds and cuts: Hydroperite has antiseptic properties, helps to clear pus from wounds and prevents the development of infections.
2. Treatment of dental problems: Used as a mouthwash for inflammatory diseases of the gums and mouth, such as gingivitis, stomatitis, as well as for removing plaque and whitening teeth.
3. Skin care: Used to treat acne and acne due to its antiseptic properties. It can also be used to lighten age spots and freckles.
4. Hair bleaching: In cosmetology, hydroperite is used as a means to lighten hair, because it is able to destroy melanin, the pigment that gives hair color.
5. Surface disinfection: In some cases, hydroperite may be used to disinfect medical equipment and surfaces in the home.

Release form

Hydroperite is available in the form of tablets for preparing a solution for topical and external use. The main active ingredient of the tablets is urea peroxide (hydroperite), and each tablet contains 1.5 g of the active ingredient.

Pharmacodynamics

The mechanism of action of Hydroperit is based on its ability to release molecular oxygen by interacting with the enzymes catalase and peroxidase in tissues. This release of oxygen provides antiseptic, hemostatic (stopping bleeding), and antimicrobial action. Hydroperite, being a complex compound of hydrogen peroxide and urea, when decomposing not only cleans the treated surface, but also has a deodorizing effect. The effect of using Hydroperite is temporary, it reduces the number of microorganisms on the surface, but does not provide complete sterilization.

This process of decomposition and release of oxygen also contributes to the cleansing of wounds from pus and blood, facilitating their healing. Molecular oxygen released during this process actively oxidizes various biological substrates and microorganisms, which determines the antiseptic effect of the drug.

Pharmacokinetics

The pharmacokinetics of hydroperitol describes how the substance is absorbed, distributed, metabolized, and excreted in the body after administration.

When hydroperite comes into contact with skin or wounds, it rapidly decomposes to form active oxygen (mainly hydrogen peroxide), which has an antiseptic effect. Active oxygen can kill bacteria and other microorganisms by oxidizing their cell structures. Hydrogen peroxide can also help remove dead cells and clean wounds.

Absorption of hydroperitol through the skin is usually minimal as it is rapidly degraded at the site of application. However, if it enters the gastrointestinal tract (e.g., accidental ingestion), hydrogen peroxide may be absorbed and broken down by the enzyme catalase into water and oxygen, potentially causing side effects such as abdominal bloating or discomfort.

Metabolism of hydroperitol occurs mainly in the liver with the participation of the enzymes catalase and peroxidase, which contribute to its decomposition to harmless substances (water and oxygen). The excretion of hydroperitol metabolic products is mainly through the lungs (as oxygen) and kidneys (as water).

Dosing and administration

The method of use and dosage of hydroperit may vary depending on the form of release and intended use. Here are general recommendations for the use of hydroperit in tablet form:

For wound care:

1. Preparation of solution: Dissolve 1-2 hydroperitol tablets (each tablet contains 1.5 g of perhydrol, equivalent to approximately 0.5 g of hydrogen peroxide) in 100 ml of water. A 0.5% or 1% hydrogen peroxide solution will be obtained.
2. Application: Apply the solution directly to the affected area with clean absorbent cotton or gauze. You can also wash the wound with the solution.

For mouth and throat rinses:

1. Preparation of solution: Dissolve 1 tablet in a glass of water (about 200 ml) to make about 0.25% solution.
2. Use: Rinse your mouth or throat with the solution for 1-2 minutes, then spit it out. Do not swallow the solution.

Important points:

• Do not use undiluted hydroperite: Alwaysdilute tablets as directed before use.
• Avoid contact with eyes: If the solution gets into the eyes, flush immediately with plenty of water.
• Single use: The ready solution is best used immediately after preparation, do not store.
• Check expiration date: Do not use expired tablets.

Use Hydroperite during pregnancy

The use of hydroperitol during pregnancy requires caution and should be under medical supervision. Although hydroperitol has antiseptic properties and may be useful for disinfecting wounds and treating some skin diseases, its effects on pregnancy and fetal development have not been fully studied.

In general, topical preparations are considered safer during pregnancy than oral preparations because they have less systemic effects on the body. However, even with external use, it is important to consider the following points:

• Concentration and frequency of use: High concentrations and frequent use may increase the risk of adverse reactions.
• Area of application: Avoid use on large areas of skin or on areas with damaged skin, as this may lead to increased absorption into the bloodstream.
• Skin sensitivity: During pregnancy, the skin may be more sensitive and the risk of irritation or allergic reactions may increase.

Contraindications

Hydroperite has a number of contraindications to use, among them:

1. Individual intolerance or allergic reaction to the components of the drug. This is the main and most important contraindication, as allergic reactions can be serious.
2. Skin diseases, including dermatitis, eczema, psoriasis, and other skin lesions. Applying hydroperitol to damaged or inflamed skin may aggravate the condition.
3. Pediatric age. The use of hydroperitol in children may be limited due to increased skin sensitivity and risk of adverse reactions. It is important to consult a doctor before using the product to treat children.
4. Pregnancy and lactation. Although there may be insufficient direct data on the effect of hydroperitol on the fetus or newborn during breastfeeding, its use during these periods should be approached with caution and only after consultation with a physician.
5. Combination with other medicines. Hydroperitol may interact with some other drugs, especially those used externally, enhancing or altering their effects. It is important to inform your doctor about all medications you are taking before starting to use hydroperitol.
6. Use on large areas of skin. Due to the risk of absorption and possible systemic side effects, the use of hydroperitol on large areas of skin may be undesirable.

Side effects Hydroperite

Side effects of Hydroperit, like any medical drug, depend on the individual sensitivity of the patient and conditions of use. The most commonly reported side effects are:

• Burning at the site of application: This is the most common side effect associated with direct contact of the solution with the wound surface or mucous membrane.
• Allergic reactions: In individual cases, allergic reactions may occur, which are manifested as skin rashes, itching, redness or swelling at the application site.
• Hypertrophy of the tongue papillae: In prolonged use for mouth rinses, hypertrophy of the tongue papillae may develop due to frequent and prolonged contact of the drug with oral tissues.

It should be remembered that the drug is intended for topical and external use only. In case of adverse reactions, it is recommended to stop using Hydroperit and seek medical attention.

Overdose

Overdose with hydroperitol when applied externally is rare, but is possible if the drug is used in excessively high concentrations, on large areas of the body or too often. With internal administration, such as accidental ingestion, the risk of overdose increases, which can lead to serious health consequences.

Symptoms of a hydroperitol overdose may include:

• Skin irritation, redness, burning and discomfort when applied externally.
• If swallowed - sharp pain in the abdomen, vomiting, diarrhea, foam in the mouth, in severe cases - internal burns of the esophagus and stomach.
• Dizziness, headache and general malaise.
• In very severe cases, Quincke's edema, anaphylactic shock, or severe organ dysfunction, especially with a high ingested dose.

What to do if you suspect an overdose:

1. In external application - immediately rinse treated areas with plenty of water.
2. If swallowed, seek medical attention immediately. Do not induce vomiting on your own without medical advice, as this may aggravate esophageal burns.
3. Provide the casualty with access to fresh air and a comfortable position.
4. Follow further recommendations from medical professionals, which may include taking antacids, pain relievers, or other medications to reduce symptoms.

Interactions with other drugs

Hydroperite (urea peroxide) may interact with various medications, altering their effectiveness or increasing their side effects. It is important to pay attention to the following aspects of interaction with other drugs:

1. Interaction with topical preparations: Hydroperitol may interact with other topical preparations, especially those containing metals, leading to chemical reactions with oxygen release and possible skin burns. An example of such an interaction would be the use of hydroperitol with preparations containing silver, lead or mercury.
2. Interaction with skin products containing thiols or phenols: These components may react with hydrogen peroxide, reducing its antiseptic effect or causing undesirable chemical reactions on the skin.
3. Antiseptics and other disinfectants: Combining hydroperitol with other antiseptics may increase or, conversely, decrease the effectiveness of the treatment, depending on the specific substances. For example, concomitant use with alcohol may increase dryness and irritation of the skin.
4. Drugs that alter the redox balance in the body: Hydroperite as an oxidizing agent can affect the action of drugs that also affect redox processes in the body.

Storage conditions

The storage conditions for Hydroperit are quite simple and similar to the storage requirements for many other medical products:

• Store in a dry place protected from light. This prevents decomposition of the active substance by moisture and light.
• The storage temperature should not exceed 20°C. Observance of this condition contributes to preservation of stability and efficacy of the drug.
• It is necessary to keep the drug out of the reach of children to avoid accidental ingestion or misuse.

Shelf life

The shelf life of Hydroperit is usually 2 years from the date of manufacture, after which it is not recommended to use the drug as its safety and efficacy may be reduced.