Orinol plus

Orinol plus is a systemic drug with antihistamine and anti-edema activity. Used in the treatment of certain diseases affecting the nasal cavity.

Phenylephrine hydrochloride is an α-adrenomimetic.

Phenyltoloxamine citrate is a substance that blocks the action of histamine H1-terminations; also has anticholinergic and antihistamine properties.

The chlorphenamine component also blocks the activity of histamine H1-terminations, and in addition, it demonstrates an intense anti-exudative effect.

Indications Orinola plus

It is used to eliminate the symptoms of year-round and seasonal rhinitis of an allergic nature, and besides this for vasomotor rhinitis, sinusitis and ARVI.

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Release form

The release of the drug is made in capsules, 10 pieces inside the box.

Pharmacodynamics

Phenylephrine hydrochloride, exerting a vasoconstrictor effect, reduces mucosal edema in the upper part of the respiratory tract, as well as in the paranasal sinuses.

Phenyltoloxamine citrate reduces tearing, rhinorrhea and other manifestations of allergies and colds, which appear due to excessive exudation.

Chlorphenamine reduces the swelling of the mucous membrane of the respiratory ducts and removes signs such as sneezing, tearing, rhinitis, and nasal itching.

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Dosing and administration

The medication is prescribed to take on the 1st capsule with 8-12 hour breaks. The drug is taken orally, without reference to food intake. The duration of the course of therapy is selected by the doctor.

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Use Orinola plus during pregnancy

Orinol plus is not used during breastfeeding and pregnancy.

Contraindications

Among the contraindications:

• strong sensitivity associated with medication elements;
• excessively elevated blood pressure;
• glaucoma of angle-closure;
• introduction together with MAOI.

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Side effects Orinola plus

The main side signs are:

• systemic disorders: xerostomia, dry mucous throat and nose, and epidermal rashes;
• problems with the work of the cardiovascular system: tachycardia, headaches and a decrease in blood pressure indicators;
• Disorders of the function of the National Assembly: dizziness, convulsions, agitation or sedation, insomnia, severe nervousness and weakening of visual acuity;
• lesions associated with the gastrointestinal tract: anorexia, constipation, stomach discomfort, vomiting, diarrhea and nausea;
• disorders affecting the urogenital tract: delay or increased urination;
• respiratory disorders: hoarseness of breath, feeling of tightness inside the sternum and nasal congestion.

[9], [10], [11], [12]

Overdose

Signs of poisoning include: dilated pupils, vomiting, dry mouth, nausea, and flushing of the skin of the face.

Requires the abolition of the drug, followed by gastric lavage and taking saline laxative and activated carbon. If necessary - the patient is hospitalized in toxicology.

[15], [16]

Interactions with other drugs

Using the drug with sedative drugs, hypnotics, tranquilizers, antipsychotics or alcohol is prohibited, because it can lead to the development of a strong suppressive effect on the central nervous system.

[17], [18], [19], [20],

Storage conditions

It is required to keep orinol plus in a closed place from the penetration of children and moisture. Temperature values - in the range of marks 15-30 ° C.

[21], [22]

Shelf life

Orinol Plus can be used for a 24-month period from the time the therapeutic product is manufactured.

Application for children

The medication is not prescribed in pediatrics (persons under the age of 12).

Analogs

Analogs of drugs are the substances Terofun, Aktifed, Koldar with Terosim, Zestra, and Trifed, and in addition, Mile Nose and Koldflu plus.

[23], [24]