Dermazol plus

Dermazol plus is an antimycotic drug with a local therapeutic effect.

[1], [2]

Indications of the dermazol plus

A medicine is used to destroy and prevent the appearance of various fungal lesions affecting the hairy area of the skin on the head, accompanied by pruritus, and, in addition, scaling:

• elimination of dandruff;
• elimination of dermatitis having a seborrheic nature;
• with pityriiform form depriving local character - in the scalp of the skin on the head.

Release form

The release occurs in the form of shampoo, in flakonchikah capacity of 50 or 100 ml. Inside the box there is one such bottle.

Pharmacodynamics

The medicinal effect of shampoo is developed due to the action of its active elements - pyrithione zinc with ketoconazole.

Ketoconazole is an artificial derivative of imidazole dioxalane having fungistatic and fungicidal properties with respect to dermatophytes (Microsporum spp., As well as Epidermophyton spp. And trichophytons), and in addition to different strains of fungi yeast-like, as well as yeast type (from the genus Candida and malassseia furfur ).

Zinc pyrithione during outdoor use has antimicrobial and antimycotic effects. Demonstrates the effectiveness of fungi, staphylococci with streptococci and other pathogenic bacteria. This element has an anti-seborrheic effect and helps to eliminate dandruff together with dermatitis having a seborrheic nature.

Shampoo, which contains ketoconazole, weakens the itching with peeling, which often occurs with dandruff, deprived of otrepid character and seborrheic form of dermatitis.

Thanks to the powder of the aloe vera plant, the hair is moistened, and at the same time the hair is enriched with various useful microelements, as well as vitamins.

Pharmacokinetics

Tests to determine the pharmacokinetic characteristics of the drug have not been performed, but there is evidence that zinc pyrithione with ketonazole after external treatment is almost not absorbed into the circulatory system and does not exert systemic influence.

Dosing and administration

Before use, shake the bottle thoroughly with shampoo.

Apply it on the pre-moistened scalp and hair - for about 3-5 minutes, and then wash the substance with warm water.

Schemes of drug use for various diseases:

• with dandruff, and with dermatitis of seborrheic nature - therapy lasts 0.5-1 month, using shampoo twice a week; in case of prophylaxis, it is required to apply the medication once per week or once a month for a half-month;
• when deprived of an otrigious character - for treatment you need to shampoo your head every day for 5 days; In case of prophylaxis, a single course should be conducted before the start of the summer season - during the 3 days, the head should be washed daily with the drug.

Use of the dermazol plus during pregnancy

With lactation or pregnancy, shampoo can be used only in situations where the likely benefits for a woman will be higher than the possibility of complications in the baby / fetus.

Contraindications

Contraindication is the presence of intolerance with respect to pyrithione of zinc, ketoconazole or other elements of the therapeutic agent.

Side effects of the dermazol plus

The use of shampoo can cause the appearance of certain side symptoms:

• lesions affecting the subcutaneous layer and skin: sensation of itching with burning, the development of erythema, dermatitis of contact nature, acne, rashes and irritation. Also there is a pustular rash on the treatment site, a feeling of discomfort, hypersensitivity, urticaria, and besides it develops dry skin and changes on the skin, and exfoliation intensifies;
• disorders in the skin appendages: increased fatness or dryness of hair, a change in their structure or color, and in addition, alopecia (all these symptoms develop in people with gray or chemically damaged hair) and discoloration of the nails. There were also reports that the naturally curly hair straightened;
• Violations of NA activities: taste disorders (dysgeusia), hypersensitivity and paresthesia;
• immune manifestations: symptoms of hypersensitivity, among which anaphylactoid signs, and in addition Quincke's edema;
• violations of the visual organs: eyelid edema, irritation affecting the eyes, and increased lacrimation;
• infectious, as well as invasive processes: the development of folliculitis.

Overdose

Because the drug is used exclusively externally, and ketoconazole almost does not penetrate the circulatory system, the likelihood of signs of intoxication is extremely low.

If the medicinal product is inadvertently swallowed, only symptomatic and supportive procedures are performed. Induce vomiting or perform gastric lavage not - to avoid aspiration.

[3]

Interactions with other drugs

If Dermazol is prescribed to people who have been using for a long time for therapy with local SCS, it is necessary to continue using the latter, with a gradual cancellation in the next 2-3 weeks (to avoid the development of withdrawal syndrome).

The likelihood of interaction with other medicines is extremely low, because the systemic absorption of shampoo is very weak.

It is forbidden to combine the drug with dermatological medicines, which contain GCS.

[4], [5]

Storage conditions

Dermazol plus should be kept in a place that is closed from penetration of young children. The temperature conditions are within 25 ° C.

Shelf life

Dermazol plus is allowed to be used for 3 years from the date of manufacture of the therapeutic agent.

Application for children

There is no data on the use of dermazol plus in children.

Analogues

Analogues of the drug are such drugs: Biffon with Skin-Cap, as well as sulfuric ointment, Perhotal with Ketozoral and Solsen Forte, and besides this shampoos Nizoral, Mycosoril, Sebozol, Tsinovit, Sulsena, Friederm and Keto plus, and also Kenazol. This list also includes Cynocap, Ecoderm with Sebopyrox, Nezo-Farm, Eberscept, Friederm (tar and zinc) and Terbinacod.

Reviews

Dermazol plus receives a lot of positive reviews, which talk about the high effectiveness of the drug in eliminating dandruff, as well as various fungal diseases affecting the skin on the head.

About shampoo basically speak in the context of its effectiveness against dandruff. Most patients note that although the drug is not cheap, it acts very qualitatively.