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Depantol
Last reviewed: 23.04.2024
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Depantol - a combined medicine that has anti-inflammatory, reparative, and with it antimicrobial properties.
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Indications Depantol
Depantol suppositories are indicated for the treatment of patients suffering from vaginitis (acute or chronic stage), and in addition exo- or endocervicitis (also with complications in the form of ectopia of the uterine neck).
The drug is also used in the complex treatment of true erosive lesions of the uterine neck.
Suppositories can be assigned to accelerate the process of regeneration of the vaginal mucosa damaged by destructive treatment methods (diathermocoagulation, cryo-, and also laser-induced constriction), and also during the postpartum period or after gynecological operations.
Release form
Produced in the form of suppositories. One blister contains 5 candles. The package contains 1-2 blister plates.
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Pharmacodynamics
The drug includes 2 active components - bigluconate chlorhexidine, as well as dexpanthenol.
Chlorhexidine is an antiseptic that has an active effect on a relatively large group of gram-negative bacteria, as well as gram-positive microbes, yeast fungi, protozoan microorganisms, and with it the herpes and dermatophyte virus. Among the strains sensitive to the substance: vaginal trichomonas, gardnerella vaginalis, E. Coli, pale treponema, ureaplasma, chlamydia, staphylococcus, streptococcus, and besides bacteroids fragilis and gonococcus. Chlorhexidine does not affect or weakly affect the strains of Proteus spp. And pseudomonads, and with it viruses (except the herpes virus), spores and acid-fast microorganisms. The substance retains its properties under the influence of pus, blood, and also some secrets.
Dexpanthenol is a prodrug that is metabolized to take the form of calcium pantothenate. This component is an integral part of coenzyme A, participates in the metabolism of carbohydrates and lipids, and besides this acetylation. Together with this, he is a participant in the binding processes of hormones GKS, acetylcholine, and in addition to this porphyrin. The substance stimulates the recovery process, stabilizes the cellular metabolism, strengthens the collagen fibers and enhances the processes of mitosis.
Suppository Depantol does not affect the activity of lactobacil.
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Dosing and administration
The drug must be administered intravaginally. The suppository must be taken from the blister just before the injection procedure. Perform the procedure should be lying on the back - the suppository should be injected deeply. Before use, wash your hands and perform standard hygiene procedures. Dosages, as well as the duration of the therapeutic course, are appointed by the attending physician.
As a rule, the dosage is 1 suppository 2 times a day.
On average, the treatment course lasts 7-10 days. It is possible to extend treatment to 20 days - it depends on the effectiveness of therapy, as well as the nature of the pathology.
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Use Depantol during pregnancy
The medicine is allowed to be used by pregnant and lactating women.
Contraindications
Among the contraindications: the presence of the patient intolerance of any of the components of the drug. Also, suppositories can not be administered to children.
Side effects Depantol
Depanctol, as a rule, has good tolerability, without causing the appearance of various adverse reactions. Sometimes, patients experience hyperemia, itching and burning sensation in the area of the vaginal mucosa, as well as on the external part of the genitals. If the patient has intolerance to the active substances of drugs, local and systemic allergic manifestations may develop.
Side effects of the drug usually disappear after the discontinuation of suppository use and do not require specific treatment.
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Interactions with other drugs
The medicine can not be combined with substances that are part of the group of anions, but also with soap (if these drugs are administered by the intravaginal method).
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Storage conditions
Shelf life
Depantol is allowed to be used for 2 years from the date of release of the drug.
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Attention!
To simplify the perception of information, this instruction for use of the drug "Depantol" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.