Calcemin

Calcemin helps to make up for lack of calcium, micro- and macro elements, as well as vitamin D, and besides it controls the process of calcium-phosphorus metabolism.

Indications Calcemin

Among the indications for the prescription of the medicine:

• a preventative against osteoporosis, as well as other pathologies of the OPA;
• preventive agent against periodontal and dental pathologies;
• replenishment of a deficiency in the body of minerals with vitamins, if there is a deficiency of these substances in the diet;
• for children during intensive growth;
• breastfeeding mothers, as well as pregnant women.

[1], [2]

Release form

It is available in the form of capsule-like tablets with a volume of 250 mg. Contained in a vial of polyethylene. One bottle can contain 30, 60 or 120 pieces.

Calcemin Advance helps to reduce the rate of bone loss, and also corrects problems with the process of calcium metabolism. Used to eliminate dental pathologies and diseases of the OPA. Assign to adults and children (12+ years). It is often prescribed for women during the pre- and postmenopausal period (in particular if HRT is prohibited). It is an integral part of the therapy of conditions in which there is a noticeable loss of bone mass.

It is the basic drug in the case of use of antiresorbents (calcitonin, HRT, as well as bisphosphonates), and in addition to this stimulant for the formation of bone tissue. It is used in systemic osteoporosis (as well as complications of the disease) and osteopenic syndrome.

Calcemin Kids are chewable tablets of a pink shade in the form of animal figures with a fruity aroma and aftertaste. They are used to supplement calcium, minerals and vitamin D in children during their intensive growth. Used at the age of 3-12 years.

Calcemin Silver helps with complex treatment of osteoporosis of different nature (senile, steroid, menopausal or idiopathic type), which is caused by a prolonged immobile state, as well as in its complications (such as fractures, etc.). In addition to this - with periodontitis and severe diseases of teeth.

It is often prescribed to people of 50 years to lower the risk of bone fractures in conditions of lack of calcium, minerals and vitamin D in the nutritional diet.

Pharmacodynamics

The medicine is a special complex consisting of useful vitamins and minerals. The calcium contained in it is the main component that feeds bone tissue. Together with this, he controls the permeability of the vascular walls and the conductivity along the neuromuscular receptors and synapses. In addition, it activates the contractile function of smooth, as well as skeletal muscles and is an essential element in the coagulation of blood. In the medicine, calcium is contained in the form of citrate salt, as well as calcium carbonate. The maximum possible number of so-called. Elemental calcium is contained in calcium carbonate. Ca3 (C6H5O7) 2 reduces the dependence of the bioavailability of the active substance on the state of the gastrointestinal mucosa, and in addition prevents the formation of stones in the urinary system, even with prolonged use. In addition, removes the excess produced parathyroid hormone.

Vitamin D (the substance cholecalciferol) helps to quickly absorb calcium, and also helps to restore and build the structure of bone tissue.

Zinc is an integral part of a variety of enzymes contained in the body (200+ species in it), the function of which is the binding of nucleic acids to proteins. In addition, this element helps growth along with cell repair and gene expression formation. Has a positive effect on the activity of the enzyme ALP.

Manganese helps the process of binding the components of bone and cartilage tissues (glycosaminoglycans). Also increases the calcium-saving properties of the vitamin D.

Copper helps to form collagen and elastin, and also prevents the demineralization of bone structures.

Boron stabilizes the activity of the hormone parathyroid gland - parathyroid hormone (it takes part in the exchange of magnesium and phosphorus, as well as cholecalciferol and calcium). The impact on the processes of minerals metabolism in parathyroid hormone does not depend on whether the vitamin D3 enters the body.

Pharmacokinetics

Calcium is absorbed from the digestive tract, and is excreted along with urine, and then with feces. Absorption of this component is due to the activity of calbbidine (this is an enzyme of the intestinal mucosa). The biosynthesis of the calbindine substance is directly dependent on calcitriol (the product of the decomposition of the vitamin D group).

Vitamin D is quickly absorbed from the intestine, passes into the liver, bone system, adipose tissue, as well as the adrenal and musculature of the heart. After the separation of this vitamin together with the bile, it is reabsorbed. Further, it is partially converted into inactive decay products.

The excretion of zinc occurs mainly through the intestine (90%), and the residue is released through the kidneys (10%).

Copper is partially absorbed from the intestine, and the residues are excreted unchanged or in the form of insoluble complexes. Along with bile, 80% of copper is eliminated, 16% - through the intestine, and the remaining 4% - through the kidneys. A small part of the substance can also be eliminated through the sweat glands.

Boron is absorbed from the intestine, and elimination occurs through the kidneys (by 90%).

Dosing and administration

Children aged 12+ years, and also adults are assigned 1 tab. 2 rubles / day. Children in the period of 5-12 years - 1 table. 1 rub. / Day. The medicine should be drunk before meals or during it. The duration of the treatment course is selected individually, there are no time frames.

For pregnant women, as well as women during the HBV, the dosage is 1 tab. 2 rubles / day. Calcemin is allowed to be administered only after 20 weeks. Pregnancy.

Use Calcemin during pregnancy

It is allowed to use the medicine during pregnancy and lactation.

Contraindications

Among the contraindications:

• individual intolerance of components of drugs (allergic reaction);
• hypercalcemia or hypercalciuria;
• nephrolithiasis.

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Side effects Calcemin

In general, adverse reactions are observed due to drug overdose: increased sensitivity to the constituent elements of Calcemin, swelling and vomiting with nausea, the development of hypercalciuria or hypercalcemia.

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Interactions with other drugs

It is forbidden to combine Calcemin with calcium channel blockers.

[5], [6], [7], [8]

Storage conditions

You need to keep the medicine in a place that is closed from the light and access of children. Temperature conditions - within 25-30 ° C.

Shelf life

Calcemin is allowed to be used for 3 years from the date of manufacture of the medicine.