Medical expert of the article
New publications
Preparations
Vestinorm
Last reviewed: 04.07.2025
All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
Vestinorm has a histamine-like effect, which helps improve microcirculation processes. The principle of therapeutic effect has been studied only partially; there are several theories regarding the effect of the drug.
Betahistine is an artificial histamine analogue, has an effect on H1-endings, acts as an antagonist of H3-endings, and also demonstrates weak activity in relation to histamine H2-endings. The active element helps to improve blood flow processes inside the vessels of the inner ear, relaxing the sphincters located in the microcirculatory system of the inner ear. At the same time, the drug enhances blood circulation inside the basilar arteries.
Indications Vestinorm
It is used in cases of Meniere's syndrome or disease, which is characterized by nausea, severe dizziness, tinnitus, hearing loss and vomiting.
Along with this, the medication is prescribed to eliminate the symptoms of dizziness (of a vestibular nature) that develop in various pathologies (postoperative dizziness during neurosurgical or ophthalmological procedures, post-traumatic encephalopathy, labyrinth, vertebobasilar insufficiency, atherosclerosis of the cerebral vessels and vestibular neuritis).
[ 1 ]
Release form
The medicinal substance is released in tablets (volume 8 or 16 mg) - 10 pieces in a blister pack. In a box - 3 or 6 packs.
Pharmacodynamics
The drug helps to create vestibular compensation and also increases the speed of vestibular activity restoration processes by regulating metabolism aimed at histamine release.
The drug's effectiveness has been confirmed by tests conducted with the participation of people suffering from Meniere's disease and vestibular disorders. This subgroup of people showed a decrease in the intensity of attacks and a reduction in their frequency.
Pharmacokinetics
After taking the tablets, the active element is absorbed at high speed in the gastrointestinal tract. After this, betahistine undergoes metabolic processes with the formation of a metabolic component - 2-pyridyl acetonate. In case of taking the drug with food, the plasma indices of the metabolic element are slightly lower than in case of taking it on an empty stomach; there is also a slowdown in the absorption process from the gastrointestinal tract. The metabolic component reaches Cmax values after 1 hour after taking the drug.
The half-life is 3.5 hours. Excretion of 2-pyridylacetonic acid occurs mainly in urine; a small part of the substance is excreted by the kidneys and with feces.
Protein synthesis rates are extremely low – about 5%.
Dosing and administration
The medication must be taken orally. It is recommended to do this after meals, swallowing the tablet whole without chewing.
The duration of treatment and the portion size are selected by the attending physician, taking into account the personal characteristics of the patient and the effectiveness of the therapy.
It is recommended to use Vestinorm in the early stages of the pathology to prevent its progression or hearing loss in the patient.
The daily serving size is between 24-48 mg.
The frequency of taking the medicine varies depending on the dosage. At a dosage of 24 mg, 1 tablet should be taken 2 times a day. Tablets of 16 mg are taken 3 times a day, 0.5-1 piece. The medicine of 8 mg is taken in the amount of 1-2 tablets 3 times a day.
The average duration of therapy is several months. Improvement of the patient's condition sometimes occurs only after 2-3 weeks of daily use of the drug.
[ 2 ]
Use Vestinorm during pregnancy
There is no information regarding the use of Vestinorm during pregnancy. The medication may only be used after discussion with a doctor.
There is no information on whether betahistine is excreted in breast milk. Whether breastfeeding should be stopped during treatment is determined by the doctor.
Contraindications
Among the contraindications:
- pheochromocytoma;
- active phase of asthma;
- peptic ulcer;
- presence of allergy to the components of the medication.
Side effects Vestinorm
Usually, the use of the drug is tolerated without complications. Most often, patients experience nausea, stomach discomfort and headaches.
In addition, there are reports of bloating, itching, allergic reactions, rash, angioedema, urticaria, and anaphylaxis.
Reducing the daily dose and taking the drug with food can eliminate some of the above-mentioned negative effects.
Overdose
In case of intoxication, nausea, drowsiness and stomach pain develop. Administration of too large doses, especially when combined with other drugs, can provoke complications in the cardiovascular system and convulsions.
Symptomatic treatment procedures are carried out. If less than 60 minutes have passed since the drug was taken, gastric lavage should be performed and enterosorbents should be taken.
Storage conditions
Vestinorm must be stored in a place away from children and sunlight at standard temperatures.
Shelf life
Vestinorm can be used for a period of 36 months from the date of sale of the therapeutic agent.
Analogues
Analogues of the drug are the substances Aviomarin, Stugeron, Avetide with Cinnarizine, Akuver and Vesticap with Betaserc, Cinnaridone and Tablets for motion sickness and nausea.
Reviews
Vestinorm receives good reviews from patients on forums. It is often prescribed to people with VSD - to eliminate unpleasant symptoms. It is also often used for dizziness and speech disorders associated with TBI.
Attention!
To simplify the perception of information, this instruction for use of the drug "Vestinorm" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.