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Yellowish or colorless gel, intended for application to the skin, which has a characteristic aroma. The active ingredient of this remedy is ketoprofen (non-steroidal anti-inflammatory substance).

Indications of the valusala

Inflammatory diseases of the joints and spine (systemic autoimmune arthritis, gout); degenerative-dystrophic diseases of the joint tissue, accompanied by pain and inflammation; inflammatory processes in the nerves and muscles; traumatic affection of joints, ligaments, tendons (sprains, dislocations, bruises); complex therapy of lymph nodes and vessels, phlebitis. 

Release form

The gel is packaged in tubes of aluminum (30g and 50g), packed in cardboard boxes with instructions for use.


The active ingredient of the gel has a pronounced inflammation-reducing effect, due to which the pain syndrome is reduced. The action of the agent is based on suppression of the production of proinflammatory mediators - prostaglandins and leukotrienes by inhibiting the activity of cyclooxygenase of the first and second type. After the application of the gel, the lysosomal membranes are stabilized, the permeability of the vessels decreases, the microcirculation of blood and lymph is improved at the site of inflammation. This helps to remove swelling, tenderness, eliminates morning stiffness, improves the patient's condition both during rest and with motor loads. 


Serum concentration of the active ingredient with repeated local use is lower by almost a hundred times than with a single dose of 150 mg. Absorption of external ketoprofen is slow, in tissues it practically does not accumulate (bioavailability does not exceed 5%). Metabolites of the active substance are acylglycuronides. Absorbed by the tissues of the body, ketoprofen is eliminated mainly by the kidneys. During the day, the body leaves approximately 90% of the applied gel.

Use of the valusala during pregnancy

In the first six months of wearing, ketoprofen can be used only if there is a significant excess of the expected benefit for the mother over the likelihood of detrimental effects on the fetus.

In the last three months of gestation, ketoprofen, as a representative of substances depressing the production of prostaglandins, may pose a risk of cardiac and pulmonary complications for the fetus, and also cause intoxication of the fetus. This substance can help reduce blood clotting in the mother and baby and activate bleeding during labor.

During lactation Valusal-gel is contraindicated. If treatment is necessary for vital reasons, breast-feeding for this time should be discontinued.


Sensitization to the active substance of the gel, other non-steroidal anti-inflammatory drugs, aspirin triad. Photosensitivity in the anamnesis.

Relapses of ulcerative lesions of the digestive system; haemorrhagia of the gastro-intestinal tract in history, chronic digestive disorder (discomfort and epigastric pain).

Violation of the integrity of the skin, exudates, rashes, infections, burns, acne. Do not use under tightly sealed dressings.

The age group is 0-15 years old.

Side effects of the valusala

Local Effects

In the treatment there may be an allergy in the form of rashes (itchy erythema, eczematous, bullous lesions of the skin) or hyperemia, extending over a larger area than the treatment area, occasionally - they can cover the entire surface of the body.

After exposure to sunlight - itching and burning, dermatitis, malignant erythema multiforme, skin necrosis.

Avoid exposure to treated areas of ultraviolet radiation (natural and in a solarium) all the time of treatment and a fortnight - after.

Common Effects

A long course and the use of excessive amounts of gel can result in:

  • to dyspeptic disorders and gastrointestinal hemorrhages;
  • skin and respiratory manifestations of sensitization, anaphylaxis;
  • weakness, drowsiness, migraine-like pain and dizziness;
  • acute renal dysfunction, interstitial nephritis;
  • due to the presence of ethanol, there may be increased dryness and hyperemia of the skin;
  • ingredients of the gel can cause allergies, including delayed;
  • elderly people constitute a risk group for the likelihood of side effects, however, there is no information that individual dosages are required at this age.

If side effects occur, discontinue use of the gel and rinse well under the running water. 

Dosing and administration

Spread and lightly rub in the skin surface in places of inflammation from three to five centimeters of the squeezed out gel twice or thrice during the day. The surface of the skin should be holistic. The maximum dose is not more than 15 g / day, which corresponds to a 28 cm squeezed column of gel. The periods of treatment are not long, depending on the specificity and severity of the pathology. Appointed by a specialist individually. The standard duration of therapy, as a rule, is from one to ten days.

The treated area does not need to be bandaged or covered with a bandage because, as the preparation is well absorbed by the skin surface, it does not stain clothes and clothes. After treatment, it is recommended to wash hands well, except when it is the place of application. In cases of prolonged therapy, it is recommended to use rubber gloves.


Local application virtually eliminates overdose due to low bioavailability of the gel.

However, high doses distributed over a large surface can cause significant side effects. First aid - rinse the place of application with running water.

Incorrect use of the gel or accidental ingestion of it can cause systemic effects (drowsiness, dyspepsia, dizziness, pain in the stomach, oppression of the respiratory function). 

Large dosages of the gel for prolonged application are associated with a risk of respiratory depression, coma, spasmodic contractions of the muscles, gastrointestinal hemorrhages, hypertension or hypotension, and acute renal impairment.

There is no specific antidote. Therapy is performed according to the symptoms. First aid, provided that no more than an hour has passed since the overdose: gastric lavage and inside - activated charcoal with sorbitol. In severe cases, immediately call an ambulance. 

Interactions with other drugs

Since the plasma concentration in the local application is low, the appearance of signs of interaction with other drugs are observed exclusively in cases of frequent application on large surfaces:

  • Possible intoxication with cyclosporine, methotrexate, lithium salts, cardiac glycosides as a result of their retention in the body;
  • increasing the effectiveness of anticoagulants, aspirin and other non-steroidal anti-inflammatory drugs, glucocorticosteroids, phenytoin, hypoglycemic drugs;
  • It is not recommended to combine application with other external agents, which contain non-steroidal anti-inflammatory drugs;
  • a combination with blood pressure lowering drugs, diuretic, mifepristone weakens the effectiveness of these drugs (the interval of use of Valusal and mifepristone should be at least eight days);
  • combination with aspirin reduces the binding of ketoprofen to plasma albumins, with probenecid - it helps to slow the elimination of ketoprofen and reduce the level of its binding to serum proteins;
  • it is recommended that medical supervision of patients who are prescribed ketoprofen in combination with coumarin.

Storage conditions

Keep in accordance with the temperature regime up to 25 ° C. Keep away from children.

Shelf life

2 years.

Last reviewed by: Aleksey Portnov , medical expert, on 01.06.2018
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To simplify the perception of information, this instruction for use of the drug "Valsal" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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