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Tardiferon
Last reviewed: 03.07.2025
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The drug with a high iron content belongs to the pharmacotherapeutic group of antianemic drugs.
Indications Tardiferone
The antianemic drug Tardiferon is used to treat hypochromic (iron deficiency) anemia, as well as after prolonged or large-scale blood loss, with poor absorption of iron from the digestive tract, with insufficient or inadequate nutrition.
In addition, Tardiferon can be used to prevent anemic conditions in women during pregnancy. For example, the prescription of Tardiferon is relevant in cases where it is not possible to ensure a constant supply of iron with food.
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Release form
Tardiferon is a tablet with prolonged activity, protected by a light (almost white) film coating. The tablets are convex on both sides, their surface is smooth.
Each Tardiferon tablet contains a ferrous sulfate compound, the amount of which corresponds to 80 mg of iron.
Tardiferon tablets contain ascorbic acid, which improves the absorption of iron in the digestive system.
The factory cardboard packaging contains three blister plates. Each plate contains 10 Tardiferon tablets.
Pharmacodynamics
Tardiferon is a representative of complex medicinal products with a high iron content and prolonged activity.
The medicine contains divalent iron sulfate ion, which eliminates iron deficiency in the blood and activates hematopoiesis processes.
The absolute safety of the drug Tardiferon is explained by the presence of mucoproteose - a natural mucopolysaccharide that creates protection for the mucous tissues of the digestive system from the irritating effect of iron ions. Mucopolysaccharide provides a gradual release of iron over several hours. This has a positive effect on the tolerability of the drug.
The presence of ascorbic acid ensures high bioavailability of iron and improves its absorption.
Pharmacokinetics
Dosing and administration
Adult patients and children over 7 years of age are prescribed 1-2 tablets daily with water, preferably before meals.
Tardiferon tablets should be swallowed without chewing or holding in the mouth for a long time.
For prevention, Tardiferon is prescribed in the amount of 1 tablet per day, or once every two days.
The duration of taking Tardiferon depends on the patient's test results: after correction of anemia and restoration of iron levels, the drug is stopped.
If a patient has been diagnosed with iron deficiency anemia, the standard course of treatment with Tardiferon can be 3-6 months.
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Use Tardiferone during pregnancy
Tardiferon is indicated for use during pregnancy. The recommended amount of medication for the prevention of iron deficiency anemia in pregnant women is one tablet per day, or once every two days, during the second and third trimesters (Tardiferon can be started from the fourth month of pregnancy).
Iron is found in breast milk in relatively small amounts - approximately 0.25 mg per day. During lactation, taking Tardiferon is allowed only after consultation with a doctor.
Contraindications
Tardiferon should not be prescribed:
- in anemic conditions not related to iron deficiency (for example, in aplastic and hemolytic anemia, megaloblastic anemia, thalassemia);
- in conditions characterized by high levels of iron in the body (for example, hemochromatosis);
- in case of impaired iron absorption (for example, after lead intoxication);
- in case of esophageal spasm, obstruction of the digestive system, intestinal obstruction, acute internal bleeding;
- in case of poor fructose tolerance, impaired glucose-galactose absorption, isomaltase-invertase deficiency syndrome;
- in children under six years of age;
- in case of hypersensitivity to the composition of the drug.
Relative contraindications are:
- colitis, enterocolitis;
- chronic alcoholism;
- severe liver or kidney damage;
- gastric ulcer and duodenal ulcer.
Side effects Tardiferone
Side effects during treatment with the drug Tardiferon are rare. They may be expressed by the following symptoms:
- hypersensitivity reactions, skin rashes;
- laryngeal edema;
- digestive disorders, darkening of stools;
- darkening of tooth enamel, stomatitis;
- skin itching, skin redness.
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Overdose
If the recommended doses of Tardiferon are significantly exceeded, signs of overdose may occur:
- nausea with vomiting;
- pain in the abdominal area, diarrhea with the release of greenish or tarry feces;
- weakness, drowsiness, cold sweat;
- weakening of the pulse, decrease in blood pressure;
- shock or comatose state.
The lethal amount of elemental iron in the body is 180-300 mg per kilogram of human weight. The toxic amount of iron is 30 mg per kilogram of weight.
At the first signs of an overdose of Tardiferon, it is necessary to induce vomiting in the victim, after which he is recommended to consume several raw eggs and/or whole milk.
When potentially lethal amounts of Tardiferon are taken, chelation treatment with deferoxamine is performed:
- 5-10 g of deferoxamine orally (dissolve the contents of 10-20 ampoules in clean water and drink);
- 1-2 g of deferoxamine as an intramuscular injection once every 3-12 hours;
- intravenous drip infusion of 1 g deferoxamine.
If necessary, shock and acidosis are treated. In cases of severe renal dysfunction, peritoneal or hemodialysis is recommended.
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Interactions with other drugs
The absorption of iron from the drug Tardiferon is impaired by:
- antacid drugs based on aluminum, magnesium, calcium salts, as well as medications whose action is aimed at reducing the acidity of gastric juice;
- preparations based on carbonates, oxalates, phosphates, bicarbonates;
- preparations based on pancreatic enzymes.
Tetracycline drugs, black tea, and egg yolk mutually impair absorption.
Ascorbic acid and ethyl alcohol improve iron absorption. However, the latter increases the risk of toxic effects of treatment.
Tardiferon impairs the absorption of zinc preparations.
It is not recommended to carry out treatment with several drugs with a high iron content at the same time.
Storage conditions
Store Tardiferon in normal room conditions, out of reach of children. Do not allow direct sunlight to hit the packaging with the drug.
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Shelf life
Tardiferon is stored for no more than 3 years.
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Attention!
To simplify the perception of information, this instruction for use of the drug "Tardiferon" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.