Tamsulostad for the minimum period of time and is fully absorbed in the digestive tract.
Absorption can be inhibited if there is a lot of food in the stomach. The kinetics of the drug is linear.
The maximum possible content of the active component in the serum is detected after six hours.
The connection with plasma proteins reaches 99%. The volume distribution is small - no more than 0.2 liters / kg.
For Tamsulostad, the effect of "first passage" is not characteristic. The drug component undergoes a slow metabolism in the liver, where active products are formed, which retain increased selectivity to alpha 1- adrenoreceptors. A larger amount of the drug component is in the blood stream in unchanged form.
Tamsulostad is excreted by the kidneys: 9% of the drug is excreted unchanged. The half-life with a single use of Tamsulostad is 10 hours.