Medical expert of the article
New publications
Preparations
Sodium thiosulfate for cleansing the body: how to take?
Last reviewed: 04.07.2025

All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.

Diseases in the human body occur for various reasons, and one of these reasons is considered to be the excessive accumulation of various toxic substances in it. Therefore, not so long ago, specialists began to actively use the method of antitoxic "cleansing" of the body, removing harmful compounds, radionuclides, decay products and other "harmful things" from it. Sodium thiosulfate has become especially popular among patients: cleansing of the body occurs gently and quickly, and both the circulatory system and the digestive tract get rid of unnecessary substances.
What is this cleanse? Who is it suitable for and who is it not? Will thiosulfate cause harm to health?
Indications sodium thiosulfate
Sodium thiosulfate is a pharmaceutical combination product that belongs to the group of antidote drugs (specific antidotes, antitoxic drugs). Thiosulfate helps rid the body of harmful and toxic compounds.
While reading the instructions, you can learn about the medicinal properties of sodium thiosulfate:
- stops the inflammatory process;
- prevents the development of allergies;
- inhibits the development of parasites;
- neutralizes and removes toxic substances;
- cleanses fabrics.
Sodium thiosulfate is mainly used for the rapid recovery of patients with intoxication (including alcohol), as well as skin diseases, joint diseases, gynecological problems, and tuberculosis.
Sodium thiosulfate is often prescribed for psoriasis, namely, during an exacerbation of this disease. The drug has a powerful detoxifying and anti-inflammatory effect, helps reduce the number of rashes and accelerates the onset of remission.
Thiosulfate is actively used for gynecological problems: cystic formations, infertility of unknown genesis, endometriosis. The effect of treatment usually does not take long to come - of course, subject to proper use and under the supervision of a doctor.
During treatment with sodium thiosulfate, general improvements in well-being are observed. A person becomes more cheerful, energetic; the condition of the skin, hair, and nails improves.
Cleansing the body with sodium thiosulfate after chemotherapy, after long-term and strong toxic effects on the body is one of the main uses of the drug. After a full course of therapy, the function of many organs improves, digestion improves, hair growth is stimulated, weakness and apathy disappear, and the mental state of patients is optimized. Many note the strengthening of memory and activation of work capacity.
Other indications for treatment with sodium thiosulfate:
- swelling;
- systematic headaches, migraines;
- liver dysfunction, endocrine disorders;
- joint pathologies;
- allergic processes, bronchial asthma;
- frequent depressive states, moderate mental disorders.
Sodium thiosulfate alleviates hangover symptoms, eliminates cravings for alcohol, and reduces addiction.
- Sodium thiosulfate for allergies is indicated in the acute course of the process. The drug eliminates unpleasant allergic manifestations, cleanses the skin, facilitates breathing, and improves the functioning of the digestive system. However, for preventive purposes - for example, to prevent the occurrence of an allergic reaction, taking thiosulfate is useless.
- Sodium thiosulfate is often used for weight loss: this remedy is affordable and effective, as it helps remove excess fluid from the body, facilitates metabolic processes, and improves liver function. Appetite returns to normal, and the general condition improves. To achieve maximum effect, it is important to combine the course of taking thiosulfate with changes in nutrition: you need to increase the percentage of plant foods in the diet, exclude fatty, salty, and fried foods. In addition, you need to drink water: at least two liters per day.
- Sodium thiosulfate is used in gynecology due to the following beneficial properties of the drug: it stops the development of inflammatory processes, improves metabolism, removes "ballast" substances and toxins from the body, stabilizes hormonal levels. The drug is often used in the complex therapy of endometrioid and dermoid cystic formations, infertility of unknown genesis, fibroids, etc.
- Sodium thiosulfate for acne and other skin problems is perhaps one of the most common uses of the drug. Patients say that during the first 3-4 days the problem of rashes may worsen, which is associated with increased removal of toxic substances from tissues. However, then the condition begins to improve quickly: acne disappears, the inflammatory process subsides, allergies pass, hormonal levels stabilize, local immunity is strengthened.
Release form
Sodium thiosulfate can be purchased in pharmacies in the form of powder or 30% solution (ampoules of 5, 10 or 50 ml).
The active ingredient is sodium thiosulfate itself, and the auxiliary ingredients include: sodium bicarbonate, disodium edetate, injection water.
The solution is colorless (or slightly colored), transparent.
The drug belongs to the category of antidotes.
Names
Other possible names for sodium thiosulfate:
- sodium hyposulfite;
- sodium sulphate;
- sodium hyposulphate;
- sodium salt of thiosulfuric acid;
- sodium thiosulfur;
- sodium hyposulphate.
Sodium thiosulfate is the most common name of the drug, so you should ask for this option in pharmacies.
Pharmacodynamics
Sodium thiosulfate has several medicinal properties at the same time:
- counteracts, removes and neutralizes toxins;
- stops the development of inflammatory processes;
- prevents and alleviates allergic manifestations, reduces the body's allergic predisposition.
Na thiosulfate serves as a supplier of sulfur ions and can be used as a basic substrate by the thiocyanate complex system in the body for the production of non-toxic thio compounds.
Sodium thiosulfate has antidote properties and can be used in cases of intoxication with hydrocyanic acid or cyanides, arsenic, mercury, lead, iodide and bromide compounds. Against the background of the intoxicating effect of arsenic, mercury and lead, it forms a number of non-toxic sulfites. Against the background of the effect of cyanides, it forms low-toxic thiocyanate compounds.
Pharmacokinetics
The drug can be used internally, externally and as an intravenous infusion. Oral use of thiosulfate has not been sufficiently studied at the moment.
When administered intravenously, the active ingredient quickly penetrates into the intercellular fluid and is excreted unchanged in the urine.
The half-life is 0.65 h.
The pharmacokinetic effects of the drug when applied externally have also been little studied.
Dosing and administration
There are several ways to cleanse the body with sodium thiosulfate. Let's look at the most common ones.
- Cleansing by taking the solution internally is perhaps the most popular use of this medication. How to drink thiosulfate solution correctly? Mix one 10 ml ampoule of the drug with 200 ml of water (if the patient's body weight is more than 70 kg, then the dosage is increased - for example, twice, but not more than 30 ml / day). The resulting solution is drunk in two doses: half should be drunk in the morning 1 hour before breakfast, and the second half - in the evening, before going to bed, 2-3 hours after eating. The duration of the body cleansing course is from ten days to one week.
- Cleansing the body with sodium thiosulfate according to Kondakova is carried out for ten days. In the evening, mix 10 ml of the preparation with 200 ml of water or saline solution, drink on an empty stomach immediately before bedtime (1-2 hours should pass after dinner).
- How to administer sodium thiosulfate intravenously? Intravenous administration is performed only by a medical specialist in an outpatient setting. The standard administration is 1000 mg/m² per day, by drip, with 250-500 ml of physiological solution (5% glucose solution can also be used). A single dose of the drug for intravenous infusion may not exceed 2 g (equivalent to 20 ml of 10% thiosulfate). The maximum daily amount of the drug is 4 g (or 40 ml of 10% thiosulfate). Duration of therapy is up to 4 days, after which a break of 3-4 days should be taken. The total possible duration of treatment is up to 4 weeks.
The body's cleansing will not be complete if the intake of thiosulfate is not combined with certain changes in nutrition. Thus, all patients undergoing such therapy should remember the following rules:
- During treatment, you should not overeat or drink alcohol;
- you should exclude from your diet coffee, smoked foods, spices and soda, fresh milk, butter, cream and sour cream, baked goods and sweets, mayonnaise, fatty foods;
- you can eat plant products, kefir, porridge, fish dishes, honey;
- It is essential to drink at least 2 liters of clean fresh water per day.
[ 25 ], [ 26 ], [ 27 ], [ 28 ]
Application for children
According to the instructions, sodium thiosulfate is not prescribed to pediatric patients due to the lack of clinical data on the drug's effect on the child's body. However, in practice, this medication is still used: for example, to treat atopic dermatitis, psoriasis, and hypersensitivity reactions.
For the treatment of children, a 3% solution is taken orally, the dosage is calculated individually depending on the child's age. Only a qualified doctor has the right to make such a prescription, and direct treatment is carried out exclusively under his strict supervision.
Without compelling indications, supposedly to cleanse the child’s body, the drug is not prescribed.
Use sodium thiosulfate during pregnancy
Pregnant women, as well as nursing women, use thiosulfate only in cases of severe poisoning with mercury, lead or arsenic compounds, hydrocyanic acid, iodide and bromide salts, if there is a threat to the patient's life. Thiosulfate is not used to cleanse the body during pregnancy.
General cleansing is recommended to be done in other, more gentle ways. For example, it is recommended to make changes to the woman's diet to improve the digestive system. You should drink sufficient amounts of liquid, walk in the fresh air more often, have a good rest and get enough sleep. These simple methods also contribute to active cleansing of the body and favor the normal development of the unborn child.
Contraindications
Unlike most medications and antidotes, thiosulfate has a short list of contraindications. For example, it cannot be used to cleanse the body in the following cases:
- in case of increased sensitivity of the body to the ingredients of the drug;
- during pregnancy and lactation;
- in childhood (without special indications).
Self-medication with thiosulfate is not encouraged at all, even if it is carried out for the purpose of cleansing the body. Any use of this drug should be discussed with a doctor.
Harmful effects of sodium thiosulfate
Thiosulfate may not only not help, but also cause harm if the patient suffers from the following diseases:
- severe decompensated kidney disease;
- severe pathologies of the cardiovascular system;
- severe anemic conditions.
If a person has stones in the bile duct, he should also avoid cleansing with sodium thiosulfate, as taking the drug can cause an attack of biliary colic - an exacerbation of calculous cholecystitis.
Patients suffering from diabetes, gastric ulcer, duodenal ulcer, and immunodeficiency syndrome should be careful when using this treatment.
And in no case should you practice self-medication: sodium thiosulfate is a harmless, at first glance, but very powerful drug. Without skill and experience, treatment can cause irreparable harm to the body.
Side effects sodium thiosulfate
Thiosulfate can cause some side effects that anyone who wants to use the drug for body cleansing purposes should be aware of:
- difficulty breathing, shortness of breath;
- nausea, unpleasant "hydrogen sulfide" belching, vomiting, frequent loose stools, bloating and increased gas formation;
- headache, dizziness, noise or ringing in the ears, transient visual impairment;
- hypotension (in severe cases – up to hypotensive collapse), increased heart rate, pain along the venous vessels;
- allergies, fever, joint pain;
- redness of the skin, hot flashes, fever;
- frequent urination, feeling of weakness;
- local reactions (pain, redness at the site of intravenous administration of thiosulfate).
Overdose
Incorrect calculation of the dose, administration of excessive amounts of sodium thiosulfate for cleansing the body can cause deterioration of the patient's condition. Most often, an overdose is detected when the following painful symptoms appear:
- joint pain;
- strengthening of reflexes;
- convulsions;
- psychotic disorders (agitation, hallucinations);
- digestive disorders, diarrhea, vomiting;
- increased side effects.
In case of such symptoms, the intervention of a medical specialist is necessary. The use of hemodialysis, the prescription of supportive and symptomatic drugs are indicated.
Interactions with other drugs
Cleansing should be done gently, non-aggressively, so as not to create additional stress for the body. To do this, it is necessary to exclude the possibility of negative interactions of thiosulfate with other substances and medications. You need to know about such interactions before starting treatment.
- The combination of thiosulfate with drugs whose metabolic processes include the stage of thiocyanate formation may lead to a minimization of the therapeutic effect.
- Thiosulfate can neutralize the effect of medications that contain iodine and bromine compounds.
- Thiosulfate cleansing and alcohol consumption are incompatible (the body's reaction may be unpredictable).
In addition, experts do not recommend the simultaneous oral administration of sodium thiosulfate and sorbent drugs.
Thiosulfate, which is administered intravenously, is not compatible with any other medication in the same syringe.
[ 36 ]
Storage conditions
Ampoules with sodium thiosulfate solution are stored in normal room conditions, away from direct sunlight and household heating devices. Storing ampoules in the refrigerator is not advisable, and in the freezer is prohibited.
If the solution in the ampoule becomes cloudy or a sediment forms in it, then such a drug is considered unsuitable for therapeutic use.
The solution diluted for oral administration must be consumed within 24 hours.
Analogues
According to the active ingredient, there are the following analogues of thiosulfate:
- Sodium Thiosulfate Darnitsa;
- Sodium Thiosulfate Biolek.
Other antidotes with a similar mechanism of action, but with a different active component in the composition, are:
- Acizol (solution, encapsulated preparation);
- Braidan (injection solution);
- Hepaval (Glutathione, powder for preparation of injection solution);
- Zorex (encapsulated preparation based on unithiol and calcium pantothenate);
- Methionine (tablet preparation);
- Naloxone (injection solution);
- Protamine (injection solution);
- Calcium tetacin (injection solution based on sodium calcium edetate).
The use of analogues must be agreed upon with the attending physician: independent replacement of drugs is unacceptable.
Doctors' reviews
Cleansing the body itself is a good idea, because with age, tissues and the circulatory system become clogged, the liver loses its former efficiency, and resources are depleted. Living in large cities, in industrial areas, near highways leaves a particularly negative imprint on our health. According to doctors, sodium thiosulfate is the best choice in such a situation - this drug is effective, affordable, and relatively safe.
Doctors recommend that patients suffering from psoriasis and atopic dermatitis undergo cleansing annually: renewed body tissues recover more quickly after damage, become healthier and stronger, and perform their functional purpose better.
In case of liver, pancreas or intestinal diseases, it is advisable to repeat the cleansing 1-2 times a year: this is what gastroenterologists advise. This will help reduce the risk of relapse of diseases present in the body in a chronic form.
Thiosulfate cleansing helps strengthen the immune system. This is important for people who often suffer from colds and inflammatory diseases, as well as for those who suffer from osteochondrosis and have problems with metabolic processes.
In endocrinology and gynecology, thiosulfate is actively used by doctors for such diseases as mastopathy, fibroids, endometriosis, and infertility. Periodic "cleansing" is especially recommended for patients living in ecologically unfavorable regions or in areas of increased radioactivity.
Patient Reviews
You can find a lot of reviews on the Internet about the use of sodium thiosulfate. Of course, there are different opinions among them - from admiring to extremely negative. Many patients who have undergone a cleansing course note the following improvement in their condition:
- the appearance of lightness, vigor, mobility;
- relief from drowsiness, apathy, depression;
- improved digestion;
- relief of chronic pain in joints and back;
- improving the condition of the skin, hair and nails;
- elimination of skin problems (allergic rashes, acne, spots, psoriatic plaques, papillomas).
Immunity is restored, problems associated with poor environmental conditions, consumption of low-quality products, and an unhealthy lifestyle disappear.
Doctors prescribe the drug both intravenously and for internal use. However, both methods have their "disadvantages". Thus, according to users, injection is sometimes accompanied by pain in the veins, "collapse" of the venous vessels, unpleasant pulling sensations in the body. Internal use of the solution may be accompanied by temporary indigestion, foul-smelling loose stools, unpleasant belching, increased gas formation. Of course, not everyone has such symptoms. And to avoid them, treatment should be carried out against the background of changes in nutrition and lifestyle, and under the supervision of a doctor.
In general, the following conclusions can be made: thiosulfate cleanses the body qualitatively. But the treatment should be prescribed and monitored by a doctor, in order to avoid complications and unpleasant additional symptoms.
Attention!
To simplify the perception of information, this instruction for use of the drug "Sodium thiosulfate for cleansing the body: how to take?" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.