Sebidin

Sebidin is a medicine used to treat diseases of the bronchi and lungs. Let's consider the basic rules and features of using the drug.

Sebidin is a pharmacotherapeutic group of drugs used to treat colds. It has antibacterial, bactericidal and antiseptic properties. The local combination drug is effective in the symptomatic treatment of lesions of the mucous membrane of the pharynx of infectious and inflammatory origin.

Indications Sebidina

The drug contains active components that are effective against colds. Let's consider the main indications for the use of Sebidin:

• Infections of the mouth, throat and larynx.
• Inflammatory lesions of the gums.
• Periodontosis.
• Periodontitis after surgery.
• Periodontopathy.
• Aphthous stomatitis.
• Gingivitis.
• Chronic recurrent aphthae.

The drug is used for various forms and degrees of severity of the above diseases.

Release form

The dosage form of Sebidin is lozenges. The capsules are pink-orange in color, flat with beveled edges. One package contains 20 tablets in blister packs.

Active ingredients of the tablets: chlorhexidine dihydrochloride 5 mg, ascorbic acid 50 mg. Excipients are: sucrose, magnesium stearate, methylcellulose, talc and fruit essence.

Sebidin Plus. A popular remedy for the treatment of colds is Sebidin Plus. This medicine contains two active components - ascorbic acid 75 mg and chlorhexidine dihydrochloride 5 mg. The tablets have vitamin and antiseptic properties. Chlorhexidine has an antibacterial effect, and its low concentrations - a bacteriostatic effect. Ascorbic acid reduces swelling and inflammation, enhances the immune response and improves the tissue regeneration process.

• The drug is prescribed to treat symptoms of inflammation of the mucous membrane of the throat and larynx.
• For patients over 12 years of age, 1 lozenge is prescribed 3-4 times a day, i.e. every 6 hours. It is better to use the product after meals. The course of treatment should not exceed 14 days.
• Sebidin Plus is contraindicated for patients under 12 years of age, in case of hypersensitivity to the active components and for patients with phenylketonuria. Before using the tablets during pregnancy, it is necessary to consult with the attending physician.

Temporary changes in taste sensations are possible while taking the medicine. Long-term use of the tablets may cause slight staining of the teeth and tongue.

Pharmacodynamics

The active components of Sebidin destroy bacterial cell membranes. Pharmacodynamics indicate the antioxidant properties of ascorbic acid, slowing down the aging process of cells and stimulating immunity. Chlorhexidine affects gram-positive and gram-negative microorganisms, promotes wound healing.

Pharmacokinetics

Since Sebidin is in the form of lozenges, the active components do not penetrate into the systemic bloodstream, but have a local effect. The pharmacokinetics of the active components indicate weak absorption of chlorhexidine into the gastrointestinal tract from the mucous membranes. Ascorbic acid is quickly absorbed and penetrates into all tissues of the body.

Dosing and administration

Depending on the severity of the pathological condition, the method of application and dosage of Sebidin depend. The tablets are used for resorption. The recommended dosage is 1 tablet 3-4 times a day. The duration of therapy should not exceed 7 days. In particularly severe cases, treatment can be extended to 21 days.

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Use Sebidina during pregnancy

The possibility of using Sebidin during pregnancy is determined by the attending physician. To date, there is no reliable clinical data on the safety of the drug for the fetus and when used during breastfeeding.

Contraindications

Sebidin has absolute and relative contraindications for use, let's consider them:

• Patients are under 12 years of age.
• Intolerance to the components of the drug.
• Fructose intolerance.
• Isomaltase/sucrase deficiency.
• Glucose-galactose malabsorption.

With special caution and only after a doctor's prescription, the medication is used for diabetes mellitus, glucose-6-phosphate dehydrogenase deficiency, kidney stones, hemochromatosis, during pregnancy and lactation, and hyperoxaluria.

Side effects Sebidina

The use of Sebidin may cause the following side effects:

• Nausea, vomiting, bowel disturbances.
• Painful sensations in the epigastrium.
• Temporary disturbances of taste sensations.
• Mumps.
• Soreness of the tongue and mucous membranes.
• Discoloration of the tongue, fillings and teeth.
• Skin allergic reactions.

Side effects from laboratory parameters are also possible: neutrophilic leukocytosis, glucosuria, thrombocytosis, suppression of the function of the insular apparatus of the pancreas and other atypical symptoms that require medical consultation.

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Overdose

Since Sebidin is practically not absorbed into the gastrointestinal tract, an overdose of the drug is practically impossible. If this happens, more pronounced side effects appear. Symptomatic therapy and examination by a doctor are indicated to eliminate them.

Interactions with other drugs

Very often, complex therapy is used for lung and bronchial diseases. Interactions with other drugs must be carefully monitored. Thus, organic substances taken simultaneously with Sebidin reduce its effectiveness. Medicines that contain ethanol enhance the effect of the tablets.

Chlorhexidine is pharmaceutically compatible with cationic drugs and is incompatible with alkaline and anionic compounds. Ascorbic acid in combination with indirect anticoagulants and heparin reduces their effectiveness. When interacting with benzylpenicillin and tetracycline, their concentration in the blood plasma increases. Vitamin C reduces the concentration of oral contraceptives in the blood, and tricyclic antidepressants reduce tubular reabsorption.

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Storage conditions

According to the storage conditions, the tablets should be kept in a place protected from sunlight and inaccessible to children. The drug should be in the original packaging. The storage temperature should not exceed 25 °C.

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Shelf life

Sebidin and Sebidin Plus have a shelf life of 36 months from the date of manufacture (indicated on the packaging with the tablets). After this time, the medication should be disposed of. Taking expired tablets is dangerous to health. This is due to the high risk of developing uncontrolled side effects.