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Revalgine
Last reviewed: 23.04.2024
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Revagin is an analgesic antispasmodic drug of non-narcotic nature.
Indications of the rivalgina
It is used for pains against which there are spasms in the area of smooth muscles in the internal organs:
- renal or hepatic colic;
- spasm in the region of the ureter;
- colic in the gastrointestinal tract;
- dysmenorrhea spastic nature;
- dyskinesia ZHVP.
Also, the medicine eliminates pain arising from sciatica, neuralgia, and also arthralgia. It is used as an auxiliary medicine for anesthesia after surgical operations or during diagnostics. In addition, it can be prescribed to reduce fever and treat inflammations and infections.
Together with this, injections of Revalgine solution can be used for migraines, headaches, and also myalgia.
Release form
The release occurs in tablets, as well as in an injection solution.
Tablets are packed in blisters, in an amount of 10 pieces in each. Inside the pack - 2 or 10 such plates.
The solution is produced in ampoules with a volume of 2 ml. Inside the box there are 5 ampoules. Also, ampoules can have a volume of 5 ml, 5 of each ampoule inside the blister pack. In the box - 5 or 25 of these ampoules.
Pharmacodynamics
Revagin is a complex drug, an antispasmodic and an anesthetic. It contains elements of fenpiverinium bromide, sodium metamizole, as well as the hydrochloride of the pitophenone. The properties of the drug are due to the effects of medicinal components.
Pitophenone is an antispasmodic with a powerful myotropic effect, similar in its effect to papaverine. Pitophenone reduces the increased smooth muscle tone, removes spasms, and besides it has analgesic effect for pains of a spastic nature.
Sodium metamizole is an NSAID, which is based on the element pyrazolone. Metamizole has anti-inflammatory, analgesic and antipyretic properties, therefore it helps to reduce the binding of cytokines of a pro-inflammatory nature. Due to this, an intensive decrease in inflammation is observed first.
Bromide fenpiverinia - a holinoblokator, which with the help of anticholinergic processes helps to relax the smooth muscles of internal organs.
All the active elements of the drug potentiate the properties of each other, thereby increasing the overall effectiveness of the drug.
Pharmacokinetics
Sodium metamizole is partially synthesized with blood proteins, subjected to metabolic processes inside the liver, and then excreted in the urine, and also in the form of metabolic products.
Dosing and administration
Use of an injection solution.
Revalgine is administered parenterally, both in / in, and / m method. Before the introduction of intramuscularly, you should warm the ampoule to the temperature of the body. You need to inject into the buttock area. The drug effect develops after 20-30 minutes.
When IV injection, the rate of injection should be slow - the rate should be 1 ml / minute. During the introduction should monitor blood pressure, heart rate, as well as respiratory function. The duration of such treatment is determined by the doctor.
Use of tablets.
The drug can also be administered orally. Tablets are recommended to eat after eating, while washing with plain water. The length of this course, as well as the size of portions, is determined by the attending doctor, each patient separately. Often a day apply 1-2 tablets. Therapy should last a maximum of 3 days.
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Use of the rivalgina during pregnancy
It is forbidden to prescribe Revalgine to pregnant women.
Contraindications
It is forbidden to apply the drug both in tablets and in solution if the patient has an increased sensitivity to the active component of drugs and other constituents of pyrazolone.
Also among the contraindications:
- expressed forms of disorders of renal or hepatic activity;
- hepatic porphyria in acute degree;
- obstruction of gastrointestinal tract;
- hypertrophy of the prostate;
- glaucoma of a closed angle;
- atony in the region of the ureter or gallbladder;
- retention of urinary processes;
- spasms of the bronchi;
- problems with the work of the hematopoietic system;
- the period of breastfeeding.
Care is needed when prescribing drugs for mild forms of hepatic or renal pathologies, gastric diseases, IHD, and heart failure of a chronic nature.
Side effects of the rivalgina
Usually the medicine is well tolerated. Adverse events were noted with the use of drugs for more than 3 consecutive days or when taking too large a dose. Among the violations:
- a disorder of the digestive function: dryness of the oral mucosa, exacerbation of the gastric ulcer or gastritis, and in addition, a disorder of the stool;
- disorders in the CNS: development of headaches, deterioration of visual acuity, accommodation disorder, and dizziness;
- CAS organs lesions: decreased blood pressure and heart rhythm instability;
- problems with the function of urination: a disorder of kidney function, delay of urination, and also oliguria. In addition, urine can acquire a red tint;
- disorders in the work of systemic blood flow: the development of agranulocytosis, anemia, as well as granulocytopenia. There may also be signs of hyperthermia, vaginitis, sore throat, proctitis, stomatitis, and chills;
- allergy symptoms: development of urticaria, TEN and Stevens-Johnson syndrome, as well as bronchial spasms, angioedema and anaphylaxis.
Overdose
As a result of poisoning, symptoms such as convulsions, dry mouth mucosa, a disorder of the hepatic or renal activity, a disorder of accommodation, and, in addition, a sensation of confusion may occur.
To eliminate the effects of an overdose, symptomatic treatment is required. Perform a gastric lavage, prescribe the intake of saline purgative drugs and enterosorbents. There is also the possibility of conducting forced diuresis or hemodialysis.
Interactions with other drugs
It is strictly forbidden to use the medicine with ethanol.
Do not prescribe the drug in combination with other non-narcotic analgesics, because this can lead to the development of toxic effects.
Oral contraception, as well as antidepressants, inhibit the hepatic metabolism of metamizole, which increases the likelihood of developing toxicosis.
Barbiturates, and in addition the other inducers significantly reduce metamizole.
Sedation medications with tranquilizers potentiate the analgesic effect of Revalgine. If these medicines need to be combined, you should first consult your physician.
Storage conditions
Revalgine is required to be kept in places that are inaccessible to children. The temperature should be kept within 15-25 ° C.
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Shelf life
Revalgine is allowed to be used for 3 years from the date of manufacture of the drug.
Reviews
Revalgine receives many positive reviews - this medicine works great for pain sensations of various origins. It works well for toothaches, migraines, and menstrual pain.
In consultation with the doctor, you can find out what other problems and disorders Remvalin is capable of coping with.
Attention!
To simplify the perception of information, this instruction for use of the drug "Revalgine" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.