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Panatus forte
Last reviewed: 03.07.2025
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Panatus forte is a medicine with a central effect to eliminate cough symptoms. It can help prevent the development of irritating dry cough. In addition, it also helps to reduce the tension of the bronchial muscles and promotes expectoration - this makes breathing easier and relieves chest pain.
Indications Panatus forte
Indications include: dry cough of any origin (including pre- and postoperative stages, as well as bronchoscopy or surgery), and whooping cough.
Release form
Available in tablets (50 mg) or syrup (200 ml). There are 10 tablets on a blister plate, one package contains 1 blister. Syrup in a glass bottle (closed with a plastic stopper, has a lid with 1st opening control). One pack contains 1 bottle together with a special dosing spoon.
Pharmacodynamics
The active component of the drug is butamirate - an antitussive substance with a central method of action on the body. It does not belong to the category of opiates. Among its properties, in addition to antitussive, are also moderate anti-inflammatory, expectorant, and at the same time bronchodilating.
Pharmacokinetics
Butamirate is completely and fairly quickly absorbed after oral administration. The substance reaches its peak plasma concentration 1 hour after taking the drug. The half-life is 6 hours. After a repeated course of taking the drug, the concentration of the active substance in the blood remains linear, and no accumulation of butamirate is observed.
Butamirate is metabolized by hydrolysis to 2-phenylbutyric acid and diethylamino-ethoxy-ethanol. These breakdown products also have antitussive properties.
Butamirate together with its decay products has a practically maximum (approximately 95%) binding rate with plasma proteins – this explains the long period of their half-life, as well as the long antitussive effect on the body. The substance is excreted mainly through the kidneys.
Dosing and administration
The medicine is taken orally, before meals.
For adults, the dosage is as follows: syrup, 3 measuring spoons 4 times a day; tablets, 1 piece 2-3 times a day.
For children over 12 years old – syrup, 3 measuring spoons three times a day; tablets, 1 piece 1-2 times a day.
For children aged 6-12 years – syrup, 2 measuring spoons three times a day.
For children 3-6 years old – 1 measuring spoon three times a day.
Use Panatus forte during pregnancy
There is no information on whether the drug is safe to take during pregnancy, or on the extent of its penetration through the placental barrier. It is not recommended to take Panatus Forte in the 1st trimester. In the future, the drug may only be used with the permission of the attending physician.
Contraindications
Among the contraindications:
- individual intolerance to the active substance, as well as other components of the drug;
- lactation period;
- The syrup is prohibited for children under 3 years of age, and the tablets are prohibited for children under 12 years of age.
In case of renal failure, the drug should be prescribed with special caution.
Side effects Panatus forte
Taking Panatus forte can cause the following side effects: vomiting with nausea, skin rashes, diarrhea and dizziness. These symptoms disappear after reducing the dosage or stopping the medication.
Overdose
As a result of accidental overdose, the following symptoms may develop: vomiting with nausea, abdominal pain, drowsiness, diarrhea, impaired coordination of movements, severe irritability, and decreased blood pressure.
In case of a mild overdose, no treatment is required, but in case of a severe overdose, the patient will need immediate emergency care: gastric lavage, activated charcoal and saline laxatives, and in addition, procedures to support the functioning of the respiratory and cardiovascular systems.
Interactions with other drugs
[ Storage conditions
The medicine should be kept in normal conditions - a dark, dry place, inaccessible to children. Temperature conditions - maximum 25°C.
Shelf life
Panatus forte in tablet form can be used for 5 years; in syrup form – 4 years.
Attention!
To simplify the perception of information, this instruction for use of the drug "Panatus forte" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.