Orinol Plus

Orinol Plus is a systemic medication with antihistamine and decongestant activity. It is used to treat certain diseases affecting the nasal cavity.

Phenylephrine hydrochloride is an α-adrenergic agonist.

Phenyltoloxamine citrate is a substance that blocks the action of H1-endings of histamine; it also has anticholinergic and antihistamine properties.

The component chlorphenamine also blocks the activity of histamine H1-endings, and in addition demonstrates an intense anti-exudative effect.

Indications Orinola Plus

It is used to eliminate the symptoms of year-round and seasonal rhinitis of allergic origin, as well as vasomotor rhinitis, sinusitis and acute respiratory viral infections.

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Release form

The medicine is released in capsules, 10 pieces per box.

Pharmacodynamics

Phenylephrine hydrochloride, having a vasoconstrictor effect, reduces swelling of the mucous membranes in the upper respiratory tract, as well as in the paranasal sinuses.

Phenyltoloxamine citrate reduces lacrimation, rhinorrhea and other manifestations of allergies and colds that appear due to excessive exudation.

Chlorphenamine reduces swelling of the mucous membrane of the respiratory tract and eliminates symptoms such as sneezing, lacrimation, rhinitis and nasal itching.

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Dosing and administration

The medication is prescribed to be taken 1 capsule at 8-12 hour intervals. The medication is taken orally, without reference to food intake. The duration of the course of therapy is selected by the doctor.

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Use Orinola Plus during pregnancy

Orinol Plus is not used during breastfeeding and pregnancy.

Contraindications

Among the contraindications:

• severe sensitivity associated with drug elements;
• excessively elevated blood pressure;
• closed-angle glaucoma;
• administration together with MAOIs.

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Side effects Orinola Plus

Main side effects:

• systemic disorders: xerostomia, dry mucous membranes of the throat and nose, as well as epidermal rashes;
• problems with the functioning of the cardiovascular system: tachycardia, headaches and decreased blood pressure;
• disorders of the nervous system: dizziness, convulsions, agitation or sedation, insomnia, severe nervousness and decreased visual acuity;
• Gastrointestinal disorders: anorexia, constipation, stomach discomfort, vomiting, diarrhea and nausea;
• disorders affecting the urogenital tract: delayed or increased frequency of urination;
• respiratory disorders: hoarseness, a feeling of tightness inside the chest and nasal congestion.

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Overdose

Signs of poisoning include dilated pupils, vomiting, xerostomia, nausea, and flushing of the face.

It is necessary to cancel the medication, followed by gastric lavage and taking a saline laxative and activated carbon. If necessary, the patient will be hospitalized in toxicology.

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Interactions with other drugs

It is prohibited to use the drug together with sedatives, sleeping pills, tranquilizers, neuroleptics or alcoholic beverages, because this can lead to the development of a strong depressant effect on the central nervous system.

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Storage conditions

Orinol Plus must be stored in a place closed to children and moisture. Temperature values are in the range of 15-30°C.

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Shelf life

Orinol Plus can be used for a period of 24 months from the date of manufacture of the therapeutic product.

Application for children

The medication is not prescribed in pediatrics (to persons under 12 years of age).

Analogues

The analogs of the drug are Terofun, Actifed, Coldar with Terosim, Zestra and Trifed, and in addition to this, Mili Nosik and Coldflu Plus.

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