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Health

Nebilong

, medical expert
Last reviewed: 23.04.2024
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Nebilong has antianginal, antiarrhythmic and antihypertensive properties.

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Indications Nebilonga

It is used to lower high values of blood pressure, prevent the development of attacks of IHD or angina pectoris, as well as in complex therapy of CHF.

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Release form

The drug is sold in tablets with a volume of 2.5, as well as 5 and 10 mg, packaged in blister packs. Inside the pack - 15, 50 or 105 tablets.

Pharmacodynamics

The drug is a cardioselective β1-adrenoblocker, which has a vasodilating effect. It blocks the activity of β1-adrenergic receptors and transforms the processes of production of the relaxing factor of the endothelium. Decrease in blood pressure is associated with a decrease in OPSS, BCC and cardiac output, as well as a slowing down of the formation of renin and a decrease in the sensitivity of baroreceptors.

Often, the antihypertensive effect of Nebilong occurs after 7-14 days, and the normalization of values occurs during the first month.

The medicine lowers heart rate during quiet state and loads, weakens the need of the heart muscle in obtaining oxygen, and besides it improves the level of diastolic filling, lowers the weight of the myocardium with its mass index and positively influences the daily rhythm of blood pressure values.

The drug has no effect on the metabolism of lipids.

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Pharmacokinetics

The medicine is absorbed at high speed, getting inside the digestive tract. Has a strong synthesis with blood proteins (98%).

The drug passes through the BBB and undergoes hepatic metabolism.

Excretion occurs in the form of glucuronides with feces and urine.

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Dosing and administration

Use the medication orally, in a dose of 2.5-5 mg per day (in the morning). If this is required, the dosage can be increased to 10 mg per day.

Elderly people first need to take 2.5 mg per day, and if there is a need to increase this dose to 5 mg of the substance.

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Use Nebilonga during pregnancy

Drug use during pregnancy is allowed only if there are strict medical indications, because there is a very high probability that because of it a bradycardia, hypoglycemia and respiratory paralysis will develop in the newborn, and blood pressure will decrease.

The use of drugs should be canceled 2-3 days before the expected day of delivery. If this can not be done, or if premature birth occurs, during the first 3 days of life, the baby's condition must be closely monitored.

Contraindications

Among the contraindications:

  • presence of strong sensitivity to the drug;
  • untreated pheochromocytoma;
  • presence of asthma;
  • hepatic pathology;
  • Staying in the phase of CHF decompensation;
  • cardiogenic shock;
  • Angiospastic angina angina;
  • decreased blood pressure;
  • state of depression;
  • myasthenia gravis or bradycardia.

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Side effects Nebilonga

The use of medication can cause the emergence of certain side-effects:

  • headaches, a feeling of drowsiness or fatigue, and dizziness;
  • state of depression, insomnia, paresthesia, impaired concentration and hallucinations;
  • constipation or diarrhea, dry mouth and mucous nausea;
  • puffiness, orthostatic collapse, arrhythmias, cardialgia, bradycardia, bronchial spasms and dyspnea;
  • runny nose, hyperhidrosis, local allergy symptoms and photodermatosis.

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Overdose

Poisoning with medication causes bradycardia, bronchial spasms, a decrease in blood pressure and heart failure in an acute degree.

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Interactions with other drugs

Combination of the drug with SG does not cause a potentiation of the inhibitory effect on the AB-conduction.

When the drug is combined with drugs for general anesthesia, the risk of lowering blood pressure increases and depression of reflex tachycardia occurs.

Simultaneous use with cimetidine leads to an increase in the blood values of the drug.

Medications from the group suppressing the OZ process inhibit the metabolic processes of Nebilong.

Weakening of cimetidine activity is observed when combined with sympathomimetics.

Tricyclics and barbiturates are capable of potentiating the antihypertensive properties of the drug.

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Storage conditions

Nebilong should be kept at a temperature of 25 ° C maximum.

Shelf life

Niebalong can be used within 24 months from the date of manufacture of the medicinal product.

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Application for children

In pediatrics, Nebilong is not prescribed (up to the age of 18).

Analogues

The analogues of the medication are Nebivator, Nevotenz, Bivotenz with Nebivolol, Nebilet, OD-Neb and Binelol with Nebikor Adifarm.

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Reviews

Nebilong basically receives positive feedback from patients about their therapeutic effects.

Doctors believe that the use of drugs can quickly stabilize the patient's condition. If you need to increase the medication, sometimes appoint Nebilong H (a combination of hydrochlorothiazide with nebivolol) or Nebilong AM (a combination of amlodipine and nebivolol).

Attention!

To simplify the perception of information, this instruction for use of the drug "Nebilong" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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