Naftizine

Naphthyzinum has a rapid and pronounced vasoconstrictive effect with a long duration.

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Indications Naftizine

It is used to eliminate the following pathologies:

• acute rhinitis;
• acute or chronic stage of sinusitis;
• laryngitis;
• acute eustachitis;
• use of rhinoscopy during the procedure to facilitate its implementation;
• swelling in the larynx area caused by radiation or allergies;
• mucosal hyperemia caused by surgical procedures in the upper respiratory tract.

It can also be used to eliminate ophthalmological diseases – chronic conjunctivitis and asthenopic disorders.

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Release form

The medicine is produced in the form of nasal drops, in glass bottles with a capacity of 5 or 10 ml. It can also be produced in plastic dropper bottles with a capacity of 10, 15 or 20 ml. There is 1 such bottle inside the pack.

Pharmacodynamics

The drug stimulates the activity of α2-adrenergic receptors, and in addition reduces swelling, hyperemia and exudation in the mucous membrane, and has a vasoconstrictor effect on the nasal mucosa.

For people with a runny nose, the use of drops helps to facilitate the breathing process through the nose.

After 5-7 days of using the drug, tolerance to it develops.

Pharmacokinetics

After applying the substance to the mucous membrane, it acts locally on it, narrowing the superficial vessels. Because of this, the absorption and resorptive effect of the active element do not develop. Partial absorption occurs in the case of prolonged and frequent use of drops, and this can cause an increase in blood pressure.

Dosing and administration

The drops are administered intranasally – they are instilled into each nostril. Adults require 1-3 drops 3-4 times a day (0.1% solution).

In addition, it is used for diagnostic purposes. It is necessary to clear the nasal passages and drip 3-4 drops of the drug into each of them or insert a tampon into them, which was previously moistened in a 0.05% aqueous solution. Then the tampons are left in the nose for 60-120 seconds.

If the medicine is used for inhalation procedures, then the 0.05% solution is diluted using saline in a 1:1 ratio. Such inhalations can only be performed after consulting a doctor.

Use of a pediatric form of a medicinal product.

Children are usually prescribed a 0.05% aqueous solution - for the age category of 1-6 years in a portion of 1-2 drops, and for children aged 6-15 years - in a dosage of 2 drops. The procedure is performed 1-3 times a day. If necessary, a 0.025% solution can be used. To obtain it, a 0.05% Naphthyzinum solution is diluted with distilled water.

To eliminate ophthalmological disorders, the medicine can be used only with the permission of a doctor. It is necessary to establish the appropriate diagnosis and clarify with the doctor whether Naphthyzinum can be used to treat eyes. Usually, a 0.05% solution is used for these procedures (1-2 drops instilled into the conjunctival cavity), and they are carried out 1-3 times a day. The first of these procedures should be carried out under the supervision of the attending physician.

It is also only permissible to use the drug in blocked ears with the permission of a doctor.

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Use Naftizine during pregnancy

It is believed that the use of Naphthyzinum during pregnancy is allowed only if there are medicinal indications and after a thorough assessment of the risks and benefits of its use. The same applies to the possibility of using drops during lactation.

Contraindications

Among the contraindications:

• the presence of high sensitivity to the components of the drug;
• diabetes mellitus;
• thyrotoxicosis;
• elevated blood pressure;
• severe degree of atherosclerosis;
• tachycardia;
• combined use with MAOIs, as well as for 2 weeks after completion of their use;
• severe eye pathologies.

Side effects Naftizine

The use of drops can provoke the following side effects associated with the local medicinal effect of the drug:

• hyperemia of a reactive nature;
• irritation in the nasal mucosa;
• when used for a period of more than 7 days - swelling of the nasal mucosa and atrophic runny nose.

In addition, complications associated with the general drug effect may occur: headaches, nausea, as well as tachycardia and increased blood pressure (in individuals predisposed to these disorders).

Overdose

When using the medicine for a long time or constantly exceeding the recommended dose, a person may experience an increase in blood pressure or develop a disorder of consciousness. In such cases, it is necessary to stop therapy and perform symptomatic measures.

People who have used Naphthyzinum for a long time may become dependent on this drug. To get rid of it, you should consult a doctor and then follow the individual therapeutic regimen prescribed by him.

Intoxication in children should be treated exclusively by a doctor, using symptomatic procedures.

Interactions with other drugs

It is prohibited to combine the drug with MAOIs. After finishing the use of such drugs, the use of Naftizin can be started at least 2 weeks later.

The use of drops leads to a prolongation of the medicinal effect of local anesthetics used in surface anesthesia procedures.

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Storage conditions

Naphthyzinum must be stored in a place protected from sunlight and inaccessible to small children. Freezing the substance is prohibited. Temperature marks during storage are within 10-25°C.

Shelf life

Naphthyzinum can be used for 3 years from the date of manufacture of the therapeutic agent.

Application for children

It is prohibited to prescribe the drug to infants under 1 year of age.

Analogues

Analogues of this drug are such medications as Naphthyzinum Bufus, Sanorin, Naphazoline, and Naphazoline-Ferein.

Reviews

Naphthyzinum receives many different reviews. It is considered an emergency remedy for runny nose and other diseases, but it is also noted that it can cause strong addiction. Patients say that the drug is recommended for use with severe symptoms of the disease, but at the same time, it should be avoided for several days in a row. It is very important to follow the drug instructions and take into account the contraindications of the drug.