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Health

Naklof

, medical expert
Last reviewed: 23.04.2024
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Naklof is an inhibitor of cyclooxygenase. It has analgesic and anti-inflammatory properties, and also slows down the synthesis of PG.

Indications Naklof

Among the indications for the appointment:

  • prophylactic against myosis, and in addition to inflammations, as well as yellow macular edema in the period after cataract removal or implantation of the ophthalmic lens;
  • provoked by non-infection inflammatory process, which involves the anterior parts of the eyes (chronic form of non-infectious conjunctivitis, etc.);
  • inflammatory process after trauma (due to non-penetrating / penetrating injury to the eyeball) as an auxiliary drug for local anti-infectious treatment;
  • pain due to procedures using an excimer laser.

trusted-source[1]

Release form

It is available in the form of a solution of drops for eyes in 5 ml vials.

Pharmacodynamics

NSAID, an α-toluic acid derivative that suppresses COX types 1 and 2, and in addition interferes with the metabolism of eicosatetraenoic acid and reduces the concentration of Pg in the inflammatory focus. As a result of local use of the drug, pain and swelling in inflammation of non-infectious nature are relaxed.

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Pharmacokinetics

The medicine passes into the anterior eye chamber. Peak concentrations in the conjunctiva and cornea reach half an hour after administration.

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Dosing and administration

The medicine must be buried in the conjunctival sac. Before the operation - in the amount of the 1st drop (5 times in 3 hours), after the performed operation - three drops in the dosage of 1 drop. After that, in the future, you need to instill a 1-drop drop 3-5 times a day throughout the course of treatment. In some cases, the dosage may be 1-drop 4-5 times a day.

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Use Naklof during pregnancy

The use of a solution can be allowed only in case of acute necessity.

Contraindications

Among the contraindications: individual intolerance of elements of drugs.

Carefully apply:

  • if there is a history of allergy to drugs from the category of aspirin;
  • with the aspirin triad;
  • with a superficial form of herpetic keratitis (also in anamnesis);
  • with pathologies that provoke problems with blood coagulability (such as hemophilia, but in addition, with prolonged bleeding time, as well as a tendency to develop bleeding).

trusted-source[13], [14], [15], [16], [17], [18]

Side effects Naklof

When using the solution, such adverse reactions are possible:

  • temporary burning sensation (can be mild or moderate);
  • transient loss of visual acuity immediately after instillation of drops;
  • allergy to the drug (the appearance of itching, the development of photophobia and redness of the conjunctiva).

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Interactions with other drugs

In the presence of therapeutic indications, it is possible to combine with drops containing the GCS (note that the interval between the procedures should be at least 5 minutes - to prevent the risk of washing out the active ingredients with the introduction of new doses).

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Storage conditions

It is necessary to keep the medicine in standard conditions for medicines, the temperature is within 15-25 ° C. Keep out of the reach of children.

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Shelf life

Naklof can be used for 2.5 years from the date of manufacture of the medicine. After opening the bottle - within 1 month.

Attention!

To simplify the perception of information, this instruction for use of the drug "Naklof" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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