Lecrolin

Lekrolin is a local drug with anti-allergic activity, and is used to treat ophthalmic disorders.

In the case of the use of medicinal drops, there is a weakening of the need for steroid treatment and the use of antihistamines with a systemic type of effect.

The specified drug does not prevent the occurrence of conjunctivitis with infectious genesis. The most intense antiallergic effect is observed in the case of prophylactic use of Na cromoglycate, which is the active element of the drug.

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Indications Lecroline

It is used to treat people with allergic etiology keratoconjunctivitis and conjunctivitis in the active or chronic phase.

Release form

The release of drugs is made in the form of ophthalmic drops inside the bottles (equipped with a special dropper) with a capacity of 5 ml. Inside the box - 1 bottle.

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Pharmacodynamics

The drug contains the substance Na cromoglycate, which suppresses the degranulation processes of mast cells by stabilizing their walls. The use of this component prevents the secretion of histamine and other endogenous pro-inflammatory components.

Pharmacokinetics

The absorption of the active element through the eye cornea is rather weak; inside plasma about 65% of cromoglycate is synthesized with protein. After instillation inside the conjunctival eye sac, the bioavailability level is approximately 0.03%.

Absorbed substance is excreted unchanged - along with urine and bile (the term half-life equals 80 minutes).

Dosing and administration

Bury means should be inside the conjunctival sac. Portion sizes are selected individually.

It is necessary to use 1-2 drops of the drug, which are instilled into the affected eye. It should be applied 2 times a day.

In the case of treatment of pathologies that are seasonal in nature, it is necessary to begin therapy with Lecrolin immediately after the onset of the first allergy symptoms or before the intended contact with the allergen. It is necessary to use the substance throughout the entire time of contact with allergens.

During the use of drugs, you should follow the standard safety instructions: instill the substance with exceptionally clean hands, prevent the dropper tip from contacting any surfaces, and close the bottle tightly after the procedure.

The drops contain benzalkonium chloride, which is able to demonstrate a negative effect on contact lenses. Therefore, these patients need to remove them before instillation of the drug, and put on after at least 15 minutes after the procedure. It is necessary to take into account that in case of eye diseases of allergic origin it is not recommended to wear lenses.

Use Lecroline during pregnancy

Impact on the development of the fetus after the local application of the drug was not observed. It is necessary to use drops during pregnancy, taking into account the general medical instructions belonging to the specified group of patients (it is necessary to evaluate the benefits and harms from the use of Lekrolin).

A small amount of drugs is excreted with breast milk, but when used during breastfeeding, no negative effect on the infant was observed.

Contraindications

It is contraindicated to prescribe in case of strong sensitivity in relation to Na cromoglycate and other elements of the drug (this includes the preservative - benzalkonium chloride).

Side effects Lecroline

After local administration, the drug is usually tolerated without the appearance of complications. Occasionally with the use of drops, chemosis or hyperemia, a burning sensation or a foreign object in the eye, as well as visual misting were observed.

There are single signs of an allergic origin - systemic allergy symptoms, including bronchial spasm.

Overdose

Testing with the participation of animals revealed weak toxic activity of Na cromoglycate in the case of systemic and local use. After instillation into the eyes, the likelihood of developing poisoning is very low.

If the patient has toxic signs, it is necessary to cancel the medication and consult an ophthalmologist.

Interactions with other drugs

With the simultaneous use of several local ophthalmic substances should be observed at least 15-minute breaks between the procedures for their introduction.

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Storage conditions

Lekrolin needs to be kept at temperature values in the range of marks 15-25 ° C.

Shelf life

Lekrolin can be used for a 3-year term from the date the medication was sold. At the same time, after opening the bottle, the drops have a maximum 28-day shelf life.

Application for children

Do not use the drug in persons under 4 years of age.

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Analogs

Analogs of drugs are means Kromoglin, Sulfur, Fucitalmik and Kromofarm with tetracycline, and in addition Kolbiotsin, Lizotsim, Hydrocortisone with Chloramphenicol and Dekamethoxin with Benzylpenicillin sodium salt. Also on the list are Citral, Erythromycin, Allergokrom with Allergodil, Okomistin and Solu-medrol with a Bacteriophage (staphylococcal, streptococcal, or blue-purulent).