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Lecrolin
Last reviewed: 04.07.2025
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Lecrolyn is a local medication with antiallergic activity and is used to treat ophthalmological disorders.
In the case of using medicinal drops, the need for steroid treatment and the use of antihistamines with a systemic type of effect is reduced.
The indicated medicine does not prevent the occurrence of conjunctivitis of infectious genesis. The most intensive antiallergic effect is observed in the case of prophylactic use of cromoglycate Na, which is the active element of the medicine.
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Indications Lecrolina
It is used to treat people with keratoconjunctivitis and conjunctivitis of allergic etiology in the active or chronic phase.
Release form
The drug is produced in the form of ophthalmic drops, inside bottles (equipped with a special dropper) with a capacity of 5 ml. Inside the box - 1 bottle.
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Pharmacodynamics
The drug contains the substance cromoglycate Na, which suppresses the processes of mastocyte degranulation by stabilizing their walls. The use of this component allows preventing the secretion of histamine and other proinflammatory components of an endogenous nature.
Pharmacokinetics
Absorption of the active ingredient through the cornea is quite weak; within the plasma, about 65% of cromoglycate is synthesized with protein. After instillation into the conjunctival sac, the bioavailability level is approximately 0.03%.
The absorbed substance is excreted unchanged – along with urine and bile (the half-life is 80 minutes).
Dosing and administration
The product should be instilled into the conjunctival sac. Portion sizes are selected individually.
It is necessary to use 1-2 drops of the medicine, which are instilled into the sore eye. It should be used 2 times a day.
In case of treatment of pathologies of seasonal nature, therapy with Lecrolin should be started immediately after the first symptoms of allergy or before the expected contact with the allergen. The substance should be used throughout the entire period of contact with allergens.
When using the medicine, you must follow standard safety instructions: instill the substance only with clean hands, do not allow the tip of the dropper to come into contact with any surfaces, and tightly seal the bottle after the procedure.
The drops contain benzalkonium chloride, which can have a negative effect on contact lenses. Therefore, such patients should remove them before instillation of the drug, and put them on after at least 15 minutes after the procedure. It should be taken into account that in case of eye diseases of allergic genesis, it is not recommended to wear lenses.
Use Lecrolina during pregnancy
No effects on fetal development were observed after local application of the drug. It is necessary to use drops during pregnancy, taking into account the general treatment instructions related to the specified group of patients (it is necessary to evaluate the benefits and harms of using Lecrolin).
A small amount of the drug is excreted in breast milk, but when used during breastfeeding, no negative effects on the infant were observed.
Contraindications
Contraindicated in cases of severe sensitivity to sodium cromoglycate and other components of the drug (this includes the preservative benzalkonium chloride).
Side effects Lecrolina
After local administration, the drug is usually tolerated without complications. Occasionally, when using the drops, chemosis or hyperemia, a burning sensation or a foreign body in the eye, and visual blurring have been observed.
Occasionally, signs of allergic origin are observed - systemic symptoms of allergy, including bronchial spasm.
Overdose
Animal testing has shown that sodium cromoglycate has weak toxicity when used systemically or locally. After eye drops, the likelihood of poisoning is very low.
If the patient develops toxic symptoms, the drug should be discontinued and an ophthalmologist should be consulted.
Interactions with other drugs
When using several topical ophthalmic substances simultaneously, it is necessary to observe at least 15-minute breaks between their administration procedures.
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Storage conditions
Lecrolyn should be stored at temperatures in the range of 15-25°C.
Shelf life
Lecrolin can be used for a 3-year period from the date of sale of the medicine. At the same time, after opening the bottle, the drops have a maximum shelf life of 28 days.
Application for children
The medication should not be used in persons under 4 years of age.
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Analogues
Analogues of the drug are Cromoglin, Sulfur, Futsitalmic and Kromofarm with Tetracycline, and in addition to this, Colbiocin, Lysozyme, Hydrocortisone with Chloramphenicol and Decamethoxin with Benzylpenicillin sodium salt. In addition, the list includes Citral, Erythromycin, Allergokrom with Allergodil, Okomistin and Solu-medrol with Bacteriophage (staphylococcal, streptococcal or pseudomonas).
Attention!
To simplify the perception of information, this instruction for use of the drug "Lecrolin" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.