Laticort

Laticort is a corticosteroid used to treat dermatological conditions.

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Indications Laticorta

It is used to eliminate non-infected skin lesions that manifest themselves in the form of increased keratinization and are also sensitive to local GCS: seborrheic or atopic dermatitis, contact eczema, psoriasis with erythroderma, as well as lichen planus and damage due to insect bites.

Release form

It is produced in the form of ointment, cream, and lotion (all forms 0.1%). Ointment and cream are in 15 g tubes (1 tube per pack), and lotion is in 20 ml bottles with a dispenser (1 bottle per pack).

Pharmacodynamics

The medicine is applied externally. It strengthens the capillary walls and has a strong antipruritic, anti-inflammatory, as well as anti-exudative and anti-allergic effect.

Prevents the activity of the phospholipase element, thereby inhibiting the binding processes of leukotrienes. Prevents the movement of leukocytes with lymphocytes to the area of inflammation, suppresses the proteolytic effect of tissue kinins, and at the same time prevents the appearance of fibroblasts, as well as connective tissues in the area of inflammation. In addition, the drug reduces hyperemia and manifestations of intolerance, as well as the processes of proliferation and exudation occurring in the area of inflammation.

Pharmacokinetics

After treatment of the skin surface, the drug is quickly absorbed inside. Absorption into the bloodstream is quite weak, although if the drug is applied to large areas of the body or used for a long time in combination with an airtight dressing, it can have a systemic effect. Laticort can accumulate inside the stratum corneum. Absorption of hydrocortisone is more pronounced in children.

Inside the epidermis, biotransformation of the active substance occurs, and the part of it that was absorbed inside undergoes hepatic metabolism, resulting in the formation of butanoic acid.

The decay products, as well as hydrocortisone, are excreted from the body along with bile and through the kidneys.

Dosing and administration

It is necessary to treat the affected area of skin with a small amount of the preparation – rub it in, massaging lightly. The procedure should be carried out 1-3 times a day for a period of 1-3 weeks. It is necessary to carefully monitor the size of the daily dose of the drug – it should not exceed 2 g.

If the inflammation is located on the elbows or knees (psoriasis plaques), it is recommended to use hermetic bandages.

For children, Laticort is prescribed in short courses, for a maximum of 1 week, and treatment is carried out under the supervision of a doctor.

The medicine should be applied to the face very carefully, because it can cause skin atrophy, perioral dermatitis, and in addition, telangiectasia. It is also necessary to prevent the drug from getting into the eyes.

If there is no improvement in the condition after 7 days of using the drug (or a deterioration is noted), it is necessary to discuss this issue with a doctor.

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Use Laticorta during pregnancy

It is prohibited to use Laticort during pregnancy (especially in the 1st trimester).

When breastfeeding, the medicine cannot be used systemically - it is only allowed to treat small parts of the skin (however, it is prohibited to apply it to the mammary glands).

Contraindications

Main contraindications:

• infectious lesions of the skin (fungal or bacterial origin);
• skin lesions of tuberculous or syphilitic nature;
• rosacea or mycoses;
• use of drugs for a certain period of time after the vaccination procedure;
• infants under 6 months of age;
• the presence of tumors, ulcers or wounds on the skin;
• hypersensitivity to Laticort.

Caution is required when used by people with diabetes.

Side effects Laticorta

The drug is usually tolerated without complications. Sometimes skin irritation may be expected, and in the case of prolonged use over large areas of the body, the development of systemic glucocorticoid effects.

Overdose

Signs of poisoning appear very rarely, mainly as a result of prolonged treatment of large areas of the skin - in this case, symptoms of hypercorticism are observed.

Storage conditions

Laticort is kept in normal conditions for medicines. The temperature should not be higher than 25°C.

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Special instructions

Reviews

Laticort receives mostly positive reviews. The drug is highly effective in treating lichen planus and various dermatitis. There is no information about the development of side effects as a result of its use.

Shelf life

Laticort is permitted to be used for a period of 3 years from the date of manufacture of the drug.