Typhoid fever is an intestinal infection, endemic in many developing countries. In recent years, epidemics of typhoid fever have been observed in a number of CIS countries, in Central Asia. According to WHO, more than 500,000 people die of typhoid fever every year. Most often, people are sick at the age of 5-19 years, so vaccination against typhoid should be given to schoolchildren in endemic areas. In Russia in 2007, 91 people became ill (16 children).