Hepabene

Gepabene has choleretic and hepatoprotective activity.

[1], [2]

Indications Hepabene

It is used for the following diseases:

• chronic toxic diseases affecting the liver;
• chronic hepatitis;
• GIT dysfunction (this includes conditions that develop as a result of a cholecystectomy procedure  ), in combination with other medications used for such disorders.

[3]

Release form

The release of therapeutic drug is implemented in capsules, 30 pieces inside the pack.

Pharmacodynamics

Hepabene is a complex herbal medicine that includes extracts made from milk thistle and wild rue, whose properties provide its therapeutic effect. The drug is used to stabilize the work of the liver in a variety of pathologies.

Wild rue, which contains the fumarin alkaloid, helps stabilize the amount of bile secreted, thereby facilitating its influx into the intestinal region, as well as eliminating spasms of the gallbladder and gallstones.

Silymarin, which is a component of milk thistle, has a hepatoprotective effect that develops in case of liver poisoning, having an acute or chronic form (synthesizing toxic elements with free radicals inside the liver tissue). In addition, it stimulates the processes of protein binding, has an antioxidant and membrane stabilizing effect, as well as helps to restore damaged liver cells.

Pharmacokinetics

After oral administration, the silymarin flavonoids undergo recycling processes in the intestinal and liver areas. Excretion mainly occurs along with bile.

Dosing and administration

The scheme of the therapeutic cycle is chosen individually for each patient. Capsules must be taken with food, without crushing or chewing them (swallow, washed down with plain water).

During the day it is usually required to use 3 capsules (at approximately equal time intervals). When pain occurs at night, it is allowed to use the capsule before bedtime. The daily portion can increase up to 6 pieces (this dosage is maximum), which is consumed 3-4 times per day.

[4]

Use Hepabene during pregnancy

The question of the use of medication for lactation or pregnancy must be decided by the treating doctor of the patient.

Contraindications

Among the contraindications:

• the presence of intolerance towards the components of the capsules;
• acute diseases affecting the liver and gallstones (in the acute stage).

Side effects Hepabene

Sometimes taking capsules leads to potentiation of diuresis, a variety of allergy symptoms and a laxative effect.

Overdose

At the moment, information about the poisoning Gepabene missing. If the patient accidentally took too many capsules, he should consult with his doctor.

Storage conditions

Hepabene usually contain at standard temperatures of up to a maximum of 25 ° C.

[5]

Shelf life

Hepabene can be used for a 5-year period from the date of manufacture of the pharmaceutical product.

Application for children

Gepabene prohibited from use in pediatrics.

[6]

Analogs

Analogues of the drug are such substances as Allohol, Konvaflavin, Holosas with Flamin, Holagol with Tsikvalon, and in addition to this extract of artichoke, Olimetin, Cholagogue collection No. 3, Hofitol with Leptandra Composite, Liobil with Odeston, Kavehol, tansy flowers and Phytohepatol.

Reviews

Hepabene usually receives good reviews from medical specialists - it demonstrates high efficacy for pain associated with gall bladder and liver.

Comments that are left in medical forums by patients who used the drug in combination with other drugs used in such cases are almost always positive. The development of negative symptoms (pain or a feeling of heaviness in the right hypochondrium, diarrhea, and a feeling of weakness) is rarely observed, which is not considered a serious lack of medication.