Gelarium Hypericum

Gelarium Hypericum is a drug with antidepressant and anxiolytic properties.

[1], [2]

Indications of the gelarium Hypericum

It is used to eliminate:

• disorders of psycho-vegetative nature - such as apathy and mood worsening;
• pathological symptoms of a neurotic nature;
• depressions of moderate or mild severity.

[3]

Release form

Release of the medication occurs in tablets, in the amount of 15 pieces inside the blister plate. The box contains 2 or 4 such plates.

Pharmacodynamics

The active ingredient of the medicine is St. John's wort extract. This substance prevents disruption of the processes of impulse transmission through the neurotransmitters, and in addition modulates the isolation of the element IL-6 and slows down the activity of the MAO and COMT components.

As a consequence, the patient has symptoms of depressed mood, emotional instability, tension, and anxiety.

Dosing and administration

Tablets are used orally, by swallowing whole. In order to achieve peak drug exposure and reduce the likelihood of side effects, the drug is recommended together with food.

The duration of therapy, as well as the permissible portion sizes, is selected by the attending doctor, who takes into account the type of pathology and the individual characteristics of the patient.

Adolescents and adults are often prescribed a standard dose of the 1st tablet three times a day. Last course lasts at least 1 month.

In the absence of any improvement in health after 1 month from the start of therapy, it is necessary to consult the doctor for clarification of the diagnosis and the change in the treatment regimen.

Use of the gelarium Hypericum during pregnancy

Pregnant women are not allowed to prescribe Gelarium Hypericum.

Contraindications

Among the contraindications of the drug:

• the presence of hypersensitivity to the elements of the drug;
• lactase deficiency, hypolactasia, malabsorption of fructose or glucose-galactose, as well as a lack of isomaltase or sugarase inside the body;
• photosensitivity of the skin surface in relation to ultraviolet;
• combined use with tacrolimus, cyclosporine, and in addition amprenavir and indinavir, as well as other drugs that slow down the activity of HIV protease (for example, in the case of treatment of patients with HIV-positive status). In addition, it can not be combined with irinotecan, warfarin and MAOI. If necessary, such therapy should be maintained between medication intervals intervals of at least 2 weeks;
• the period of breastfeeding.

[4]

Side effects of the gelarium Hypericum

The use of the drug can cause the appearance of allergy symptoms - such as itching and rash on the skin, and in addition its pigmentation, development of intolerance to ultraviolet, eczema and so on.

In addition, it is possible to develop disorders of the function of the NS, which manifest themselves in the form of a feeling of increased fatigue or anxiety, as well as the occurrence of a headache.

Quite often develop and side effects affecting digestive activity - in the form of abdominal pain, nausea, diarrhea, bloating, dryness of the oral mucosa, anorexia and constipation.

In addition, there may be problems in the hematopoietic system - for example, the development of iron deficiency anemia.

[5], [6], [7]

Overdose

Due to intoxication, the patient develops potentiation of dosage-dependent manifestations.

Symptomatic procedures are necessary to eliminate them. In addition, it is recommended to avoid being under direct sunlight in the period of 7-14 days.

[8]

Interactions with other drugs

Combination with the drug leads to a weakening of the medicinal effectiveness of such drugs, as anticoagulants of indirect effects (such as warfarin, fenprokumone and imatinib), and in addition the remaining cytotoxic agents, digoxin with nortriptylin, and amitriptyline. This list also includes: midazolam, theophylline, fexofenadine, methadone with benzodiazepine, and in addition simvastatin and verapamil with finasteride.

Complex treatment with antidepressants (among them sertraline, nefazodone, triptans, as well as paroxetine and buspirone) often potentiates their effect and causes the appearance of negative reactions - vomiting with nausea, sensation of confusion, anxiety or fear.

In some cases, the use of Heliperium Hypericum potentiates the photosensitizing properties of some medications: diuretics of the thiazide type, tetracyclines, and in addition piroxicam and quinolones with sulfonamides.

In addition, this medicine can prolong sleep caused by exposure to opiates or funds for general anesthesia, but it also reduces sleep that is caused by barbiturates.

There is a decrease in the antihypertensive effect of reserpine, and in addition a decrease in the indinavir and cyclosporine values inside the blood.

Combination of the drug with ethinyl estradiol, as well as desogestrel increases the likelihood of bleeding, and in addition the rate of metabolic processes.

The combination with digoxin reduces its values inside the blood, and in addition the effectiveness of the effect.

If the patient uses oral contraception to prevent unwanted pregnancies, during the period of therapy with the Hypericum Helarium, it is required to resort to other contraceptive methods.

[9], [10]

Storage conditions

Helarium Hypericum should be kept out of reach of children, in a dark and dry place at standard temperature.

Shelf life

Gelarium Hypericum is allowed to be used for 3 years from the date of release of the drug.

Application for children

Children under the age of 12 years can not be appointed Gelarium Hypericum.

Analogues

Analogues of the drug are the following medicines: Rexetin, Deprim, and in addition, Cipralex and Fluoxetine.

Reviews

Helarium Hypericum is used to eliminate various disorders that occur in the NA area. Many commentators write that before the appointment of this drug they took other medicines, but it was Gelarium Hypericum that could eliminate the negative manifestations.

The medicine is often prescribed to people with panic attacks, nervous breakdowns, a sense of fear or anxiety, as well as a rapid rhythm of the heartbeat. In addition, it is actively used as a supportive for individuals with VSD. Many patients talk about the development of a sustained and prolonged therapeutic effect.

Doctors, in their responses, say that only this medication will be taken a little. In this regard, additional psychological methods are offered - consultations with a specialist, getting positive emotions from communicating with friends and relatives, listening to soothing musical compositions, meditation, and, in addition, maintaining a stable good mood. It is this approach that helps to strengthen both the physical and emotional state.