Fibro Wayne

Fibro vein - a drug that is used in the case of varicose veins. Its active ingredient is sodium tetradecyl sulfate, which has a sclerosing effect.

A thrombus is formed in the irritation zone, closing the lumen, which is present in the area of the varicose vein enlarged. After intravenous drug administration, irritation of the venous endothelium (vein, dilated varicose veins) occurs, as a result of which parietal adhesion begins, fibrosis, as well as partial or full venous obliteration, which may be transient.

[1]

Indications Fiber Wave

Therapeutic form of the drug 0.2%, as well as 0.5% and 1% are used for sclerotherapy by injection with lesions of the superficial and small veins in the legs.

3% liquid is used for varicosity affecting the legs.

[2]

Release form

The release of the component is made in the form of injection fluid - 0.2% solution in vials with a capacity of 5 ml (10 such vial inside the pack).

0.5% and 1% solutions are sold inside 2 ml ampoules (5 ampoules per pack).

3% liquid is produced in ampoules with a capacity of 2 ml (in a box - 5 ampoules), as well as in bottles with a volume of 5 ml (in a pack - 10 cans).

[3], [4],

Dosing and administration

It is necessary to use a drug intravenously (it can be appointed as well to elderly people).

The use of 0.2% injection fluid - 0.1-1 ml of the substance is injected into the lumen of the isolated venous segment (each of the 10 zones) with further compression. You can use no more than 10 ml per serving.

0.5% and 1% solutions are used according to the scheme indicated above, but a portion of such injections is 0.25-1 ml of the substance.

3% liquid in the amount of 0.5-1 ml is injected into the region of 4 zones of the lumens of the isolated venous segment with further compression. Allowed to enter no more than 4 ml of medication.

[12], [13],

Use Fiber Wave during pregnancy

There is no information as to whether it is safe to use Fibro Wayne during pregnancy. Also, there is only limited information regarding the introduction of sodium tetradecyl sulfate in the specified period. Starting therapy is recommended after birth.

There is no data on whether the active element of the drug passes into the mother's milk.

Contraindications

The main contraindications:

• strong sensitivity associated with sodium tetradecylsulfate or other elements of the drug;
• lack of opportunity to walk (any reason);
• high likelihood of thrombosis (persons with a tendency to thrombosis);
• hormonal contraceptive use period;
• the period of HRT;
• people with severe obesity;
• regular smoking patients;
• conditions in which there are restrictions in movement;
• history of thrombophlebitis of superficial character in the active phase, pulmonary embolism or DVT;
• recent operations;
• varicosities that occur due to neoplasms in the abdominal or pelvic area in cases where they are not removed;
• common pathologies that cannot be controlled - toxic hyperthyroidism, asthma, diabetes mellitus, tumors, tuberculosis, sepsis, acute respiratory infections and pathological changes in blood parameters;
• epidermal diseases (for example, oncology of an evolutionary nature);
• valvular insufficiency with significant severity, affecting deep veins;
• arterial occlusive pathologies;
• an increase in the size of the superficial veins, which also extends to deep veins;
• phlebitis of migratory character;
• active phase of cellulite;
• acute infections.

[5], [6], [7]

Side effects Fiber Wave

Among the side effects:

• immune disorders: urticaria, shock and asthma often appear. Allergy symptoms - for example, anaphylaxis;
• problems with the work of NS: sporadic paresthesia, dizziness, migraine or weakness, headaches, and vasomotor manifestations (for example, loss of consciousness) occur sporadically. In addition, a single stroke develops, hemiplegia or hemiparesis, palpitations, as well as nerve damage associated with extravasation of drugs and temporary ischemic stroke;
• lesions of the visual organs: scotoma appears sporadically (may be ciliary);
• disorders of vascular function: often phlebitis or thrombophlebitis occur. Sometimes the spider vein is enhanced at the site of drug use. TGV (usually peripheral or muscle veins), vasculitis, pulmonary embolism, HF or vascular insufficiency, and besides, necrosis of peripheral tissues in the area of intra-arterial injection, which can provoke gangrene (often observed when injected into the posterior tibial artery, located above medial ankle), or artery spasm;
• problems with respiratory activity: there is a single dyspnea, cough or feeling of restraint in the chest zone;
• digestive disorders: diarrhea, vomiting, edema of the tongue, nausea and dryness of the oral mucous membranes;
• epidermis lesions: sometimes local skin signs of an allergic or non-allergic nature (for example, erythema, puffiness, dermatitis or urticaria) and hyperpigmentation sometimes appear. Less frequently, ecchymosis or hematoma occurs, as well as necrosis of nerve fibers with peripheral tissues;
• systemic disorders: most often there is a short burning or pain in the area of the injection. A single sensation of heat or fever appears.

[8], [9], [10], [11]

Overdose

Increasing the required portions of Fibrowein when injected into the small vessel region can cause death or pigmentation of tissues.

[14]

Storage conditions

Fibro Wayne should be kept in a dark place, closed from small children. Temperature marks - no more than 25 ° C.

[15]

Shelf life

Fibro vein can be used within the 36-month period from the moment of sale of the medication.

[16]

Application for children

It is forbidden to appoint in pediatrics.

[17]

Analogs

Analogues of drugs are such tools as Decilata solution, Trombovar and Sodium tetradecyl sulfate.

[18], [19], [20]