Endofalk

Endofalk is a complex medicine that includes a mixture of various electrolytes and macrogol. An isoosmolar fluid is obtained from it. The prepared solution is used as a bowel cleanser. The drug is a laxative, and in addition, it prevents increased gas formation.

The developing diarrhea helps to empty and cleanse the intestines. The electrolytes contained in the finished liquid are balanced in such a way as to prevent reabsorption and release of water with electrolytes, which helps to avoid the disorder of EBV indicators inside the body.

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Indications Endofalka

It is used in preparation for endoscopy or X-ray of the intestine. It can also be prescribed in preparation for operations during which the intestine should not contain chyme.

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Release form

The component is released in the form of powder for the preparation of oral liquid, inside sachets with a volume of 55.318 g; there are 6 such sachets inside the box.

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Pharmacokinetics

Macrogol 3350 is not absorbed inside the gastrointestinal tract and does not participate in metabolic processes. The drug prevents the absorption of components inside the intestine and accelerates the passage and excretion of the gastrointestinal tract contents.

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Dosing and administration

The medicine is taken orally or using a nasogastric tube - in a dosage of 0.2-0.3 liters of the prepared liquid, at 10-minute intervals. In general, you need to take at least 3 liters of the medicine, but not more than 4 liters.

The substance is taken in the evening before the procedure or in the morning, approximately 4 hours before the examination or surgery. The patient should not eat 2-3 hours before taking the drug and until the end of the examination.

The medicine should be prepared as follows: dissolve the powder from 2 sachets in cooled boiled water (0.5 l), then bring the resulting volume to 1 l. The liquid should be prepared immediately before use.

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Use Endofalka during pregnancy

There is no information regarding the use of Endofalk during pregnancy. It is used only if there are vital indications, taking into account the benefits and risks of its use; the decision regarding its use should be made by a doctor.

Contraindications

Among the contraindications:

• intestinal obstruction or suspicion of it;
• having severe colitis in the active phase;
• problems with gastric emptying;
• perforation in the gastrointestinal tract or the risk of its development;
• erosive and ulcerative lesions in the gastrointestinal tract;
• megacolon of toxic genesis;
• severe intolerance to macrogol or other components of the drug;
• dehydration;
• severe cardiovascular or renal insufficiency;
• disorders of the swallowing reflex, accompanied by a predisposition to aspiration and belching;
• impaired consciousness.

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Side effects Endofalka

Main side effects:

• problems related to the gastrointestinal tract: flatulence or fullness in the abdominal area, vomiting, irritation in the anus, nausea and abdominal pain of a spasmodic nature. If the above symptoms appear, it is necessary to increase the interval between doses of the drug or stop using it until the disorders disappear;
• CNS dysfunction: sleep problems, systemic weakness and mild disorientation;
• lesions affecting the cardiovascular system: arrhythmia or tachycardia;
• immune disorders: signs of allergy (urticaria, dermatitis or rhinorrhea);
• changes in test results: hypocalcemia appears sporadically.

Overdose

In case of intoxication, severe diarrhea develops. A significant overdose can provoke a disorder of the balance of water with electrolytes, and in addition, acid-base indicators. In such violations, it is necessary to replace the lost fluid and monitor the pH values with electrolytes.

In case of disturbance of the EBV values or acid-base level, correction is performed taking into account the detected changes.

Aspiration can cause pulmonary edema, in which case the patient undergoes intensive therapy with the use of artificial ventilation and increased pressure.

Interactions with other drugs

The absorption of medications taken together with Endofalk or several hours before it is weakened or completely stopped - due to the accelerated excretion of the medication from the gastrointestinal tract. If it is impossible to cancel the drug for strict indications, it is necessary to switch to other methods of its administration (IV or IM methods). If there are no such dosage forms for the drug, the patient should be temporarily transferred to alternative drugs.

Interactions between macrogol and enzymatic assays (e.g. ELISA) may occur.

It is prohibited to mix the finished medicinal liquid with various additives (including sugar) or other solutions.

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Storage conditions

Endofalk must be stored at a temperature not exceeding 25°C.

Shelf life

Endofalk can be used for a 5-year period from the date of manufacture of the medicine. The shelf life of the finished liquid stored at a temperature of 25°C is 3 hours, and in the case of its storage in the refrigerator (temperature in the range of 2-8°C) - 48 hours.

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Use in children

The drug cannot be prescribed in pediatrics, because experience with its use in this group is extremely limited.

Analogues

Analogues of the drug are Forlax, Fortrans and Transipeg with Polyoxidine.

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