Endofalk

Endofalk is a complex medication that includes a mixture of various electrolytes and macrogol. From it receive isosmolar liquid. The prepared solution is used as a cleansing intestinal agent. The drug is laxative, and in addition it prevents increased gas formation.

The developing diarrhea helps to empty and clean the intestines. The electrolytes contained in the finished fluid are balanced in such a way as to prevent reabsorption and excretion of water with electrolytes, thus avoiding disorder of EBV parameters inside the body.

[1]

Indications Endofalca

It is used in preparation for endoscopy or intestinal X-ray. It may also be appointed in preparation for performing operations during which no chyme should be contained inside the intestine.

[2]

Release form

The release of the component is made in the form of a powder for the manufacture of oral liquid, inside bags of 55.318 g; inside the box there are 6 such bags.

[3]

Pharmacokinetics

The element macrogol 3350 is not absorbed inside the gastrointestinal tract and is not involved in metabolic processes. The drug prevents the absorption of components inside the intestine and accelerates the passage and excretion of the contents of the gastrointestinal tract.

[4], [5]

Dosing and administration

The drug is taken orally or with the use of a nasogastric probe - at a dosage of 0.2-0.3 l of the finished liquid, at 10-minute intervals. In general, you need to take at least 3 liters of medication, but not more than 4 liters.

The substance is taken in the evening before the procedure, either in the morning, approximately 4 hours before the examination or operation. 2-3 hours before taking the drug and before the completion of the examination the patient can not eat.

You need to prepare the medicine in this way: dissolve the powder from 2 sachets in cooled boiled water (0.5 l), then bring the resulting volume to 1 liter. You need to prepare the liquid immediately before applying it.

[7]

Use Endofalca during pregnancy

There is no information regarding the use of Endofal during pregnancy. It is used only in the presence of vital indications, taking into account the benefits and risks of its use; The decision regarding admission must be made by a physician.

Contraindications

Among the contraindications:

• intestinal blockage or suspicion of it;
• having strong severity of colitis in the active phase;
• problems with gastric emptying;
• perforation in the gastrointestinal tract or the risk of its development;
• having lesions of erosive and ulcerative nature in the gastrointestinal tract;
• megacolon toxic genesis;
• severe intolerance to macrogol or other elements of the drug;
• dehydration;
• insufficiency of cardiovascular or renal function in a severe degree;
• disorders of the swallowing reflex, accompanied by a predisposition to aspiration and belching;
• disturbed consciousness.

[6]

Side effects Endofalca

The main side signs are:

• problems associated with the work of the digestive tract: flatulence or overcrowding in the abdominal zone, vomiting, irritation of the anus, nausea and abdominal pain, having a spasmodic form. With the appearance of the above manifestations, it is necessary to increase the interval between drug intakes or cancel its use until the violations disappear;
• CNS disorders: sleep problems, systemic weakness and weak disorientation;
• lesions affecting the cardiovascular system: arrhythmia or tachycardia;
• immune disorders: signs of allergy (urticaria, dermatitis or rhinorrhea);
• change of test results: hypocalcemia appears singly.

Overdose

In case of intoxication, severe diarrhea develops. Substantial overdose can provoke an imbalance of water balance with electrolytes, and besides this acid-base indicators. In case of such violations, it is necessary to replace the lost fluid and monitor the pH values with electrolytes.

In case of breakdown of the EBV values or the acid-base level, taking into account the detected changes, correction is performed.

Aspiration can cause pulmonary edema - while the patient is undergoing intensive therapy with the use of mechanical ventilation and an increase in pressure.

Interactions with other drugs

The absorption of drugs that were taken along with Endofalc or a few hours before it, is weakened or completely stopped due to the accelerated excretion of the drug from the gastrointestinal tract. If it is impossible to cancel the drug under strict indications, it is necessary to switch to other methods of its introduction (in / in or in the / m methods). In the absence of such dosage forms of the drug, the patient must be temporarily transferred to alternative drugs.

The development of interaction between macrogol and enzymatic assays (for example, ELISA) is possible.

It is forbidden to mix the finished medicinal liquid with various additives (sugar is also among them) or other solutions.

[8], [9], [10], [11]

Storage conditions

Endofalc needs to be maintained at a temperature not exceeding 25 ° C.

Shelf life

Endofalk may be used for a 5-year term from the time the medication is manufactured. The shelf life of the finished liquid stored at 25 ° C is 3 hours, and if it is stored in a refrigerator (temperature in the range of 2-8 ° C) - 48 hours.

[12], [13]

Use in children

It is impossible to prescribe medication in pediatrics, because the experience of its use in this group is extremely limited.

Analogs

Analogs of drugs are drugs Forlax, Fortrans and Tranzipeg with Polyoxidin.

[14], [15]