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Health

Infectious and parasitic diseases

Hepatitis B: treatment

Patients with viral hepatitis B must be hospitalized in an infectious disease hospital. In light form, they are limited to basic therapy (diet No. 5, fractional drink, gentle motor mode). Patients with a moderate form for certain indications (pronounced intoxication, changes in biochemical parameters, alarming in terms of development of severe course), carry out detoxication therapy: intravenously inject 5% glucose solution, polyionic solutions, up to 500-1000 ml / day.

Hepatitis B: diagnosis

Diagnosis of hepatitis B is based on the analysis of cumulative clinical and laboratory data. From clinical symptoms, the gradual onset of the disease occurs at normal or subfebrile body temperature, the predominance of infectious asthenia in the form of general lethargy, weakness, muscle or joint pain, the appearance of skin rashes.

Hepatitis B: symptoms

During acute hepatitis B, pre-jaundice, icteric periods and the period of convalescence are distinguished. The disease begins instantly. The pre-egg period lasts 1-5 weeks. Asthenovegetative (weakness, fatigue, weakness) and dyspepsia (deterioration of appetite, loss of taste sensations, nausea, sometimes vomiting, bitter taste in the mouth, heaviness and dull pain in the right upper quadrant) are characteristic.

Pathogenesis of hepatitis B

The hepatitis B virus enters the bloodstream and then into the hepatocytes, where it mainly replicates. Replication is also possible in cells of the bone marrow, pancreas, kidneys, lymphocytes, but with less intensity. After the virus is adsorbed on the surface of the hepatocyte, its outer shell is destroyed and the core-particle (nucleocapsid) penetrates the cell and then into its nucleus.

Hepatitis B

Viral hepatitis B, or hepatitis B, is a viral anthropo- nous infectious disease with contact and vertical mechanisms of transmission of the pathogen. Characterized by a cyclically occurring parenchymal hepatitis with the presence in some cases of jaundice and possible chronization.

Hepatitis E

Viral hepatitis E is an acute viral disease with a fecal-oral mechanism of transmission of the pathogen, characterized by a cyclic course and frequent development of acute hepatic encephalopathy in pregnant women.

Hepatitis A treatment

Treatment of hepatitis A is currently carried out in an infectious hospital environment, but given that hepatitis A in most cases is mild and there are almost no malignant forms or chronic hepatitis, treatment can be done at home.

Hepatitis A: diagnosis

Diagnosis of hepatitis A is based on clinical, epidemiological and laboratory data. The informativeness of these components is not the same. Clinical signs can be attributed to the category of supporting, epidemiological - leading, while the results of laboratory research are crucial at all stages of the disease.

Hepatitis A: symptoms

Symptoms of hepatitis A are characterized by a wide range of clinical signs: from inpatient subclinical forms that occur without clinical symptoms, to clinically expressed forms with bright symptoms of intoxication and rather severe metabolic disorders.

Hepatitis A: causes and pathogenesis

The causative agent of viral hepatitis A is the virus HAV (hepatitis A virus), attributed to the genus Hepatovirus in the family Picornaviridae. Morphologically, the HAV looks like a shallow, non-shell spherical particle measuring 27-30 nm in size. The genome is represented by a single-stranded RNA molecule consisting of approximately 7,500 nucleotides.

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