Corticoestroma - a very rare tumors of the adrenal cortex. They are described only in men. To date, less than 100 cases have been reported in the literature.
Androsteromas - virilizing tumors - belong to a rare pathology (1-3% of all tumors). Mostly women are ill, mainly up to 35 years. The indication of researchers for rare androsteromas in men may be due to the difficulty in diagnosing - in adult men, virilization is less noticeable and, apparently, the part of the androster passes under the guise of hormone-inactive adrenal tumors.
Glucosteroma occurs in 25-30% of patients with signs of total hypercorticism. Among other cortical tumors, it is also the most common. Patients of this group in their status are among the heaviest.
The hormone-producing tumors of the adrenal cortex are one of the topical problems of modern endocrinology. Pathogenesis and clinical picture are due to the hyperproduction of certain steroid hormones by tumor tissue.
In most cases, they are found in the intestine in the area of the ileocecal angle and in the bronchi, while they are rarely functioning. Pancreatic carcinoid is capable of secreting virtually all peptides that are characteristic of ortho- and para- endocrine neoplasms.
Ectopic secretion of ACTH-like activity is known for many organs and tissues, including the pancreas. The clinical symptom complex is expressed by glucocorticoid hypercorticism.
The unusually severe course of duodenal ulcer in pancreatic tumors was noticed as far back as 1901, but only in 1955 this combination was isolated into an independent syndrome called ulcerogenic syndrome of ulcerative diathesis (or by the name of the authors who described it - Zollinger's syndrome Ellison).
Pancreatic peptide (PP) is secreted by F-cells of the pancreas. In general, the peptide reduces the contractile function of the gallbladder, increases the tone of the common bile duct and inhibits the endocrine function of the pancreas.
Glucagon is a tumor from the alpha-cells of the islets of Langerhans, secreting glucagon, which leads to the development of a complex symptom-complex, most often including dermatitis, diabetes, anemia and weight loss.
