Diseases of the endocrine system and metabolic disorders (endocrinology)

Isolated hypogonadotropic ovarian hypofunction

It occurs as a result of insufficient stimulation of ovarian function by gonadotropic hormones (GH) of the pituitary gland. Reduced or inadequate secretion of HG by the pituitary gland can be observed with the defeat of its gonadotrophs or with a decrease in the stimulation of gonadotrophs by the lyuliberin of the hypothalamus, i.e., secondary hypofunction of the ovaries can be of hypophyseal genesis, hypothalamic and, more often, mixed - hypothalamic-pituitary.

Syndrome of depleted ovaries

To the primary-ovarian hypofunction of the ovaries is the so-called syndrome of exhausted ovaries. To describe this pathological condition, many terms have been proposed: "premature menopause," "premature menopause," "premature ovarian failure," and others.

Hypofunction of the ovaries

Ovarian hypofunction, resulting from damage at the level of the ovary itself, is primary. This form is also different in pathogenesis.

Endocrine diseases

In recent years, modern endocrinology has made significant progress in understanding the diverse manifestations of the influence of hormones on the processes of vital activity of the body.

Ectopic ACTH Production Syndrome: A Review of Information

For the first time WH Brown in 1928 described a patient with ovarian cell lung cancer who had clinical manifestations of hypercorticism: characteristic obesity, striae, hirsutism, glucosuria.

Symptoms of pheochromocytoma (chromaffinoma)

Patients with chromaffinoma can be divided into two groups. The first is cases of so-called silent tumors. Such formations are found at the autopsy of patients who died from various causes, without hypertension in the anamnesis.

The causes and pathogenesis of pheochromocytoma (chromaffinoma)

About 10% of all cases of tumors of chromaffin tissue occur in the family form of the disease. Inheritance occurs in an autosomal dominant type with high variability in the phenotype. As a result of the study of the chromosome apparatus in the family form, there were no deviations.

Pheochromocytoma (chromaffinoma): information overview

Pheochromocytoma is a catecholamine-secreting tumor of chromaffin cells, typically located in the adrenal gland. Causes permanent or paroxysmal hypertension. Diagnosis is based on measuring the products of catecholamines in the blood or urine. Visualization, especially CT or MRI, helps to localize tumors. Treatment is to remove the tumor as much as possible.

Treatment of congenital dysfunction of the adrenal cortex

Treatment of congenital adrenogenital syndrome consists in elimination of glucocorticoids deficiency and hyperproduction of corticosteroids, which have anabolic and virilizing effect.

Causes and pathogenesis of congenital adrenal cortex dysfunction

Congenital adrenogenital syndrome - is genetically conditioned, expressed in the inadequacy of enzyme systems providing synthesis of glucocorticoids; causes increased excretion of adenohypophysis ACTH, which stimulates the adrenal cortex, secreting this disease mainly androgens.

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