Diseases of the endocrine system and metabolic disorders (endocrinology)

Endocrine diseases

In recent years, modern endocrinology has made significant progress in understanding the diverse manifestations of the influence of hormones on the processes of vital activity of the body.

Ectopic ACTH Production Syndrome: A Review of Information

For the first time WH Brown in 1928 described a patient with ovarian cell lung cancer who had clinical manifestations of hypercorticism: characteristic obesity, striae, hirsutism, glucosuria.

Symptoms of pheochromocytoma (chromaffinoma)

Patients with chromaffinoma can be divided into two groups. The first is cases of so-called silent tumors. Such formations are found at the autopsy of patients who died from various causes, without hypertension in the anamnesis.

The causes and pathogenesis of pheochromocytoma (chromaffinoma)

About 10% of all cases of tumors of chromaffin tissue occur in the family form of the disease. Inheritance occurs in an autosomal dominant type with high variability in the phenotype. As a result of the study of the chromosome apparatus in the family form, there were no deviations.

Pheochromocytoma (chromaffinoma): information overview

Pheochromocytoma is a catecholamine-secreting tumor of chromaffin cells, typically located in the adrenal gland. Causes permanent or paroxysmal hypertension. Diagnosis is based on measuring the products of catecholamines in the blood or urine. Visualization, especially CT or MRI, helps to localize tumors. Treatment is to remove the tumor as much as possible.

Treatment of congenital dysfunction of the adrenal cortex

Treatment of congenital adrenogenital syndrome consists in elimination of glucocorticoids deficiency and hyperproduction of corticosteroids, which have anabolic and virilizing effect.

Causes and pathogenesis of congenital adrenal cortex dysfunction

Congenital adrenogenital syndrome - is genetically conditioned, expressed in the inadequacy of enzyme systems providing synthesis of glucocorticoids; causes increased excretion of adenohypophysis ACTH, which stimulates the adrenal cortex, secreting this disease mainly androgens.

Congenital adrenal cortex dysfunction: a review of information

Congenital adrenal cortex dysfunction is also known to doctors as a congenital adrenogenital syndrome. In recent years, the disease is described more often as "congenital virilizing hyperplasia of the adrenal cortex", which emphasizes the effect of adrenal androgens on the external genitalia.

Hypoaldosteronism

Hypoaldosteronism is one of the least studied questions of clinical endocrinology. Information about this disease is not available in the manuals and in the textbooks of endocrinology, in spite of the fact that isolated hypoaldosteronism as an independent clinical syndrome is described more than 30 years ago.

Causes and pathogenesis of primary hyperaldosteronism

Common to all forms of primary hyperaldosteronism is the low activity of renin in plasma (ARP), and different - the measure and the nature of its independence, that is, the ability to stimulate as a result of various regulatory influences. The production of aldosterone in response to stimulation or suppression is also differentiated.

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