Diseases of the genitourinary system

Scleroderma and kidney damage: diagnosis

In a laboratory study, patients with systemic scleroderma can detect anemia, moderate increase in ESR, leukocytosis or leukopenia, hyperproteinemia with hypergammaglobulinemia, elevated levels of C-reactive protein and fibrinogen.

Scleroderma and kidney damage: treatment

Treatment of systemic scleroderma at the present time consists in using three main groups of drugs: antifibrotic; anti-inflammatory and immunosuppressive drugs; vascular means.

Scleroderma and kidney damage: symptoms

There are several subtypes (clinical forms) of systemic scleroderma. Depending on the prevalence and severity of skin changes, two main forms are distinguished: diffuse and limited.

Scleroderma and kidney damage: causes

The causes of scleroderma have not been studied enough. At the present time in the development of the disease, environmental factors are of great importance. Adverse exogenous and endogenous effects (infections, cooling, drugs, industrial and household chemical agents, vibration, stress, endocrine disorders) appear to play a trigger role in the onset of the disease in people with a genetic predisposition.

Scleroderma and kidney damage

Systemic scleroderma is a polysyndrome autoimmune disease characterized by progressive fibrosis and widespread vascular pathology by the type of obliterating microangiopathy underlying the generalized Raynaud's syndrome, skin and internal organs (lung, heart, digestive tract, kidney).

Goodpasture Syndrome and Kidney Disease

Goodpasture's syndrome, caused by the presence of specific antibodies to the basal membrane of the glomerular and / or alveolar capillaries, manifests itself by pulmonary bleeding and rapidly progressive glomerulonephritis.

Mixed cryoglobulinemia and kidney damage

Mixed cryoglobulinemia is a special type of systemic vasculitis of small vessels, characterized by the deposition of cryoglobulins in the vessel wall and most often manifested by skin lesions in the form of purpura and glomeruli of the kidneys.

Schönlein-Henoch disease: diagnosis

The laboratory diagnosis of Shenlen-Henoch disease does not find any specific tests. In most patients with high vasculitis activity there is an increase in ESR. In children, in 30% of cases, an increase in the titer of antistreptolysin-0, a rheumatoid factor, an increase in the content of C-reactive protein is detected.

Schönlein-Henoch disease: symptoms

Hemorrhagic vasculitis (Shenlaine-Henoch disease) in most cases is a benign disease prone to spontaneous remissions or cure within a few weeks from the time of onset.

Schönlein-Henoch disease: causes and pathogenesis

The development of purple Shonlein-Tenoch is associated with infections, food allergies, drug intolerance, and alcohol consumption. In most cases, the disease is preceded by nasopharyngeal or intestinal infection. The development of hemorrhagic vasculitis is associated with a number of bacteria and viruses.

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