Diseases of the genitourinary system

Antiphospholipid Syndrome and Kidney Damage: Treatment

Treatment of nephropathy associated with antiphospholipid syndrome is not clearly defined, since there are no large controlled comparative studies to date assessing the effectiveness of different regimens for this pathology.

Antiphospholipid syndrome and kidney damage: diagnosis

Characteristic signs of antiphospholipid syndrome are thrombocytopenia, usually moderate (the number of platelets is 100 000-50 000 in 1 μl) and not accompanied by hemorrhagic complications, and Coombs-positive hemolytic anemia.

Antiphospholipid syndrome: causes and pathogenesis

The causes of antiphospholipid syndrome are not known. The most common antiphospholipid syndrome develops with rheumatic and autoimmune diseases, mainly in systemic lupus erythematosus.

Antiphospholipid Syndrome and Kidney Damage: Symptoms

Symptoms of antiphospholipid syndrome differ significantly in variety. The polymorphism of symptoms is determined by the localization of thrombi in the veins, arteries or small intragonal vessels. As a rule, thromboses recur either in the venous or in the arterial bed.

Antiphospholipid syndrome and kidney damage

Antiphospholipid syndrome (AFS) is a clinico-laboratory symptom complex associated with the synthesis of antibodies to phospholipids (aFL) and characterized by venous and / or arterial thrombosis, habitual miscarriage, thrombocytopenia.

Thrombotic microangiopathy: treatment

Treatment of thrombotic microangiopathy involves the use of freshly frozen plasma, the purpose of which is to prevent or limit intravascular thrombus formation and tissue damage, and maintenance therapy aimed at eliminating or limiting the severity of major clinical manifestations.

Thrombotic microangiopathy: diagnosis

Diagnosis of thrombotic microangiopathy is to identify the main markers of this disease - hemolytic anemia and thrombocytopenia.

Thrombotic microangiopathy: symptoms

A typical post-diarrheal hemolytic-uremic syndrome is preceded by a prodrome, manifested in the majority of patients with bloody diarrhea lasting from 1 to 14 days (an average of 7 days).

Thrombotic microangiopathy: causes and pathogenesis

The cause of thrombotic microangiopathy is diverse. Isolate infectious forms of hemolytic-uremic syndrome and are not associated with infection, sporadic.

Thrombotic microangiopathy and kidney damage

The term "thrombotic microangiopathy" defines a clinical and morphological syndrome, manifested by microangiopathic hemolytic anemia and thrombocytopenia, which develops due to occlusion of thrombi containing aggregated platelets and fibrin, vessels of the microcirculatory bed (arterioles, capillaries) of various organs, including kidneys.

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