Dermozolon

Dermozolone has anti-inflammatory, antipruritic, antifungal and anti-allergic properties.

Indications Dermozolon

It is used for therapy in cases of:

• dermatitis of various origins, against the background of which an infectious lesion of a bacterial or fungal nature is also observed;
• bacterial eczema (also with secondary infection);
• mycosis in the area between the fingers;
• infectious processes affecting the surface of the skin.

Release form

It is produced in the form of an ointment, in tubes of 5 g. Inside the package there is 1 such tube with ointment.

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Pharmacodynamics

Prednisolone used locally (is a component of the ointment) has a vasoconstrictive effect, in addition to this, it strengthens the strength of vascular membranes. This substance also helps to slow down the processes of fibroblast reproduction and the movement of monocytes to the site of inflammation, which prevents the spread of this process. Prednisolone also helps to stabilize lysosome membranes. In addition, it affects the exudative and alternative stages of the inflammatory process, thereby preventing its spread.

Clioquinol is an antimycotic for external use. This element helps to destroy the enzyme system of microbes with fungi. It also affects gram-positive microorganisms (enterococci with staphylococci), yeast fungi and dermatophytes.

Pharmacokinetics

After local use of the drug, prednisolone is absorbed into the bloodstream in very small quantities. In the blood, the element is in a form synthesized with transcortin and albumin. Prednisolone is biotransformed in the liver, using oxidative processes. After this, the oxidized forms of the substance undergo glucuronidation and sulfation. Part of the active component is excreted unchanged, and the second - in the form of metabolic products. The excretion route is the intestines and kidneys.

When clioquinol is used externally, it penetrates into the bloodstream in small quantities, where it is synthesized with blood protein. Part of the substance's metabolism occurs in the liver. Excretion occurs with urine.

Dosing and administration

The medication is applied to the skin surface - the affected area of the body is treated with a thin layer of medicinal ointment. The procedure is performed 1-3 times a day.

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Use Dermozolon during pregnancy

There is no confirmed information about the negative impact of Dermozolone on the body of a nursing mother or pregnant woman, which is why it is allowed to use it only with the permission of the attending physician. If possible, it is recommended to use its analogs with a softened therapeutic effect instead of this drug.

Contraindications

Main contraindications:

• presence of hypersensitivity to the drug;
• cutaneous tuberculosis;
• syphilis, as well as chickenpox;
• skin reactions that occur after the vaccine is administered;
• damage to the skin surface, as well as dermatitis;
• tumors and precancerous skin pathologies.

Side effects Dermozolon

The use of the ointment in the recommended doses does not cause any violations. But if it is applied to too large areas of the skin, or used for too long, individual side effects may develop. Among them: the occurrence of steroid acne, burning, dryness, itching and irritation on the skin, and in addition, inflammation in the sebaceous glands, the development of iodine intolerance, and along with this, telangiectasia and purpura.

Storage conditions

Dermozolone should be kept in normal therapeutic conditions. Temperature level – within 15°C.

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Shelf life

Dermozolone can be used for 24 months from the date of manufacture of the drug.

Application for children

The drug should not be used for small children under 2 years of age.

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Analogues

Analogues of the drug are such drugs as Candid-B with Lorinden C, as well as Mikozolon and Sinalar K.

Reviews

Dermozolone is a GCS that also has an additional fungicidal and antibacterial effect (topical steroid with a combined effect), which other corticosteroids cannot. This is an extremely important property, because with dermatoses of an eczema-like nature, as well as eczema, diaper rash and neurodermatitis, secondary infection is often observed. The drug Dermozolone has an extended medicinal activity, due to which its effectiveness increases. Reviews say that any ointments that contain hormones are highly effective and fast acting. This, in addition to the above properties, is one of the main advantages of the drug.

The only inconvenience, according to patients, is that the ointment is produced in small quantities, so it is extremely difficult to find at drug retail outlets. At the same time, forum users also note that the use of drugs that are analogs of the drug is ineffective compared to the action of Dermozolone.