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Dermozolone
Last reviewed: 23.04.2024
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Dermozolone has anti-inflammatory, antipruritic, anti-mycotic, as well as anti-allergic properties.
Indications of the dermozolone
It is used for therapy with:
- dermatitis of various origin, against which there is also an infectious lesion having a bacterial or fungal character;
- eczema bacterial character (also with infection of secondary type);
- mycosis in the area between the fingers;
- Infectious processes affecting the skin surface.
Pharmacodynamics
The locally used prednisolone (a component of the ointment) has a vasoconstrictive effect, in addition it strengthens the strength of the vascular membranes. Also, this substance helps slow down the reproduction of fibroblasts and the movement of monocytes to the site of inflammation, which prevents the spread of this process. Prednisolone also promotes the stabilization of lysosome membranes. In addition, it affects the exudative and alternative stages of the inflammatory process, thereby preventing its spread.
Clioquinol is an antimycotic for external use. This element helps to destroy the enzyme system of germs with fungi. It also affects gram-positive microorganisms (enterococci with staphylococci), yeast fungi and dermatophytes.
Pharmacokinetics
After the local use of the drug, the absorption of prednisolone into the circulatory system occurs in a very small amount. Inside the blood, the element resides in a form synthesized with transcortin and albumin. Prednisolone is biotransformed inside the liver, with the help of oxidative processes. After this, oxidized forms of the substance undergo glucuronization and sulfatization. Part of the active component is excreted unchanged, and the second - in the form of metabolic products. The path of excretion is the intestine and kidneys.
With external use of clioquinol, it penetrates into the circulatory system in small amounts, where it is synthesized with the blood protein. Part of the metabolism of the substance occurs in the liver. Excretion - along with urine.
Dosing and administration
The medication is applied to the skin surface - a thin layer of medical ointment treats the affected area of the body. The procedure is carried out 1-3 times / day.
[3]
Use of the dermozolone during pregnancy
There is no confirmed information about the adverse effects of Dermozolone on the body of a nursing mother or pregnant woman, which makes it possible to use it only with the permission of the attending physician. If there is such an opportunity, it is recommended to use instead of this medicine its analogs with a softened therapeutic effect.
Contraindications
The main contraindications:
- the presence of hypersensitivity to the drug;
- cutaneous tuberculosis;
- syphilis, as well as chickenpox;
- reactions to the skin that occur after the introduction of the vaccine;
- damage to the surface of the skin, and in addition dermatitis;
- tumors and precancerous skin pathologies.
Side effects of the dermozolone
The use of ointment in recommended portions does not cause any disturbance. But, if it is applied on too wide areas of the skin, or used for too long, some of the side effects can develop. Among them: the occurrence of steroid acne, burning, dryness, itching and irritation on the skin, and in addition inflammation in the sebaceous glands, the development of intolerance against iodine, and with it telangiectasia and purpura.
Storage conditions
Dermozolone is required to be maintained in the usual therapeutic conditions. The temperature level is within 15 ° C.
[4]
Shelf life
Dermozolone is allowed to be used for 24 months from the date of manufacture of the drug.
Application for children
The drug can not be used for young children under 2 years old.
[5]
Analogues
Analogues of the drug are such drugs as Candid-B with Lorinden C, and in addition Mikozolon and Sinalar K.
Reviews
Dermozolone is a SCS, which also additionally exerts a fungicidal and antibacterial effect (a topical steroid with a combined effect), which other corticosteroids can not. This is an extremely important property, because with eczema-like dermatoses, as well as eczema, intertrigo and neurodermatitis, infection of a secondary type is often observed. The drug Dermozolone has an extended drug activity, so that its effectiveness increases. Reviews say that any ointment, in which there are hormones, have a high efficiency and speed of exposure. This, in addition to the above properties, is one of the main advantages of the drug.
The only inconvenience, according to the patients, is that the ointment is produced in small quantities, so at the points of sale of medicines it is extremely difficult to find. At the same time, forum users also note that the use of drugs that are analogues of the drug is ineffective in comparison with the action of Dermozolone.
Attention!
To simplify the perception of information, this instruction for use of the drug "Dermozolone" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.